Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Donald B. Purkall"'
Publikováno v:
Journal of the Neurological Sciences. 165:160-169
We used rat myelinated dorsal root ganglion (MDRG) cultures to study antibody and complement-mediated mechanisms of peripheral demyelinating diseases. Heat inactivated serum from a patient (LT) with peripheral neuropathy and a monoclonal IgM reactive
Publikováno v:
Journal of Immunological Methods. 202:213-216
Thrombospondin (TSP), a platelet glycoprotein, was purified from platelet supernatants applied sequentially to Sepharose 4B and heparin-agarose affinity columns. This TSP inhibited alternative pathway activity in serum as assessed by lysis of rabbit
Publikováno v:
European Journal of Immunology. 25:1481-1484
Activation of the alternative complement pathway of serum produces complexes of properdin (P) and C3 as measured in a double antibody enzyme-linked immunosorbent assay. When purified from serum, these complexes decrease factor B hemolytic activity in
Publikováno v:
The American journal of medicine. 82(3 Spec)
A nine-year-old white boy with recurrent pneumococcal bacteremia is described. His serum had no hemolytic activity in either the classic or alternative complement pathways. Absence of classic pathway activity was secondary to a homozygous deficiency