Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Donald Apanovitch"'
Publikováno v:
Current pharmaceutical biotechnology. 11(7)
Systems biology focuses on the roles of cellular pathways and networks rather than single biomolecules to describe biological function. A systems view of biology requires technology that can generate and quantitatively analyze, large multi-dimensiona
Autor:
Qihong Zhao, Margaret F. Favata, Donald Apanovitch, Jean H.M. Feyen, Vanessa Dell, Mark O. Cunningham, Mary Ellen Cvijic, James M. Trzaskos, William R. Foster, Carl P. Decicco, Percy H. Carter, Andrew J. Tebben, Michele H. French, Rui-Qin Liu, Ada Staal, Ming Lei, Joseph Tamasi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(16)
Once-daily s.c. administration of either human parathyroid hormone (PTH)-(1–84) or recombinant human PTH-(1–34) provides for dramatic increases in bone mass in women with postmenopausal osteoporosis. We initiated a program to discover orally bioa
Autor:
Kim Arndt, Lei Chen, Wenyang Zhong, Donald Apanovitch, Jiyang Yu, Max Follettie, Ying Gao, Paul A. Rejto
Publikováno v:
Molecular Cancer Therapeutics. 12:A33-A33
Pooled small hairpin RNA (shRNA) screening emerges as a powerful tool for loss-of-function studies in mammalian cells and searching for novel or synthetic lethality-based therapeutic targets of human tumors. Next-generation sequencing (NGS) is becomi
Autor:
Yufen Zhao, Litai Zhang, Marco M. Gottardis, Liang Schweizer, Weifang Shan, Paul A. Elzinga, Georgia Cornelius, Yuwei Tang, Arvind Mathur, Ricardo M. Attar, Janet Dell-John, Maria Jure-Kunkel, Ashvin Gavai, Cheryl A. Rizzo, Mary Ellen Cvijic, Andrew Nation, Gregory D. Vite, Aaron Balog, Derek J. Norris, Donald Apanovitch, Gregg Masters, Mary T. Obermeier, Joel F. Austin, Melissa Yarde, Gennaro Dito, Lisa S. Sharma, William R. Foster, Wen-Ching Han, Punit Marathe, Celeste Twamley, Benjamin M. Johnson, Dauh-Rurng Wu
Publikováno v:
Cancer Research. 70:5782-5782
The development and progression of prostate cancer is known to be dependent on androgens and their signaling mediated by the androgen receptor (AR). The primary therapeutic intervention involves using agents that lower serum testosterone (e.g., LHRH