Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Donald A. Lazure"'
Autor:
Runna Moussa, R. Armour Forse, Peter A. Burke, Donald A. Lazure, Peter Thomas, Aniruddha Ganguly, Olga Bajenova
Publikováno v:
Journal of Endotoxin Research. 12:352-357
Using a combination of gel-exclusion chromatography and ligand binding with [125I]-lipopolysaccharide (LPS), we discovered two novel endotoxin-binding proteins, p31LPB and p34LPB, in Kupffer cells. Their molecular masses suggest that these are previo
Publikováno v:
Cell Biochemistry and Biophysics. 30:287-301
Kupffer cells, a majority of the body's fixed macrophages, are a major site of bacterial lipopolysaccharide (LPS) metabolism and are mediators in the body's response to sepsis. Uptake of LPS is different in Kupffer cells than other macrophages. Signa
Publikováno v:
Clinical & Experimental Metastasis. 16:703-712
We hypothesize that a major factor regulating hepatic metastasis is the ability of CEA (carcinoembryonic antigen) producing colorectal carcinomas to activate Kupffer cells. CEA and NCA (nonspecific cross-reacting antigen) bind to an 80 kDa Kupffer ce
Publikováno v:
Archives of Biochemistry and Biophysics. 328:151-157
The receptor-mediated interaction of Kupffer cells with carcinoembryonic antigen (CEA) has led to the identification of an 80-kDa CEA-binding Kupffer cell protein. This study is aimed at the isolation and analyses of this protein from rat Kupffer cel
Autor:
Donald A. Lazure, Aniruddha Ganguly, Hiroshi Hayashi, Peter A. Burke, R. Armour Forse, Olga Bajenova, Peter Thomas
Publikováno v:
The Journal of surgical research. 148(2)
Bacterial endotoxins are the principal agents causing sepsis and septic shock. Cytokine cascades produced by cellular interactions to endotoxins can cause cardiovascular failure followed by multi-organ failure and death. Endotoxin intravenously admin
Autor:
Donald A. Lazure, Aniruddha Ganguly, Olga Bajenova, R.A. Forse, Hiroshi Hayashi, Peter Thomas
Publikováno v:
Journal of Surgical Research. 130:324-325
Publikováno v:
Cancer letters. 118(1)
Carcinoembryonic antigen (CEA), an intercellular adhesion molecule and a mediator of hepatic metastasis, is processed by an 80 kDa receptor on murine and human Kupffer cells in the liver. Activation of rat Kupffer cells in vitro by CEA via the 80 kDa
Publikováno v:
Shock. 21:63