The α and Δ isoforms of CREB1 are required to maintain normal pulmonary vascular resistance.

Autor: Lili Li, Katherine Howell, Michelle Sands, Mark Banahan, Stephen Frohlich, Simon C Rowan, Roisín Neary, Donal Ryan, Paul McLoughlin

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e80637 (2013)

Chronic hypoxia causes pulmonary hypertension associated with structural alterations in pulmonary vessels and sustained vasoconstriction. The transcriptional mechanisms responsible for these distinctive changes are unclear. We have previously reporte

Externí odkaz: https://doaj.org/article/0438c1ab1e9a44b9a5f63cce020f4d9f

Hyponatraemia secondary to terlipressin for gastric variceal bleeding – A case report

Autor: Mairead M. Hennessy, Donal Ryan

Publikováno v: International Journal of Surgery Open. 43:100494

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70cc1eab03de235edba0e0004dc06ea6
https://doi.org/10.1016/j.ijso.2022.100494

Scour Concerns for Short-Span Masonry Arch Bridges

Autor: Brian Solan, Robert Ettema, Donal Ryan, Gerard Hamill

Publikováno v: Journal of Hydraulic Engineering. 146

Short-span masonry arch bridges constitute a significant proportion of the existing bridge inventory in the UK, Ireland, Europe, and the northeastern United States. These historic structure...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2bab082916b326540b9cf5210e0c4ddf
https://doi.org/10.1061/(asce)hy.1943-7900.0001675

Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial

Autor: Natalie Mitchell, Vanessa Quinn, Keith Couper, Jean Antonelli, Lia McNamee, Janice Montgomery, Akesh Dhrampal, Alison Hall, Ronald Carrera, Henrik Reschreiter, Samantha Hendry, Stephen T. Webb, Maurizio Cecconi, Teresa Melody, Jonathan Hackett, Emer Neau, Peter Hampshire, Sarah Hierons, Gareth Sellors, Zoe Beardow, Ron Daniels, Pratik Sinha, Colette Seasman, Dawn Kelly, Carolyn S. Calfee, Katarzyna Zamoscik, Mike Gillies, Chris Smalley, Fiona Wade-Smith, Stephen G. Ward, Carole Schilling, Alexander Binning, Cecilia O'Kane, Kulwant Dhadwal, Timothy S. Walsh, Laura Youds, Lisa Sleight, Clair Harris, Pam Ramsay, Aisling Clarkson, Stephen Drage, Amy McInerney, Murthy Buddhavarapu, Kirsty Everingham, J A Wood, Daniel Martin, Kayla Harris, Corrienne McCulloch, Cliona McDowell, Griania White, Dorothy Breen, Julie Dawson, David Rogerson, Luigi Camporota, Kallirroi Kefala, John G Laffey, Brian Marsh, Archana Paikray, Lynn Gilfeather, Andrew Burtenshaw, Kevin L. Delucchi, Kate McGuigan, David Hope, Syed Farjad Sultan, Abby Brown, Sinead O'Kane, Melissa Rosbergen, Paula Meale, Daniel F. McAuley, Anna Walker, Julie Patrick-Heselton, Noel Hemmings, Sarah James, Arlo Whitehouse, Willis J Peel, Michael A. Matthay, Louise Boardman, Julie Wollaston, John G. Laffey, Sundeep Kaul, Andrew Gratrix, Paul Jefferson, Ged Dempsey, David Shaw, Alistair Nichol, Daniel Hadfield, Veronica McInerney, Ingeborg Welters, Katie Sweet, Samantha Hagan, Conor Bentley, Karen Williams, Tom Trinick, Manu Shankar-Hari, Heidi Dawson, Andrew Johnston, Stephen Graystone, Daniel McAuley, Banwari Agarwal, Julie Camsooksai, Victoria Martinson, Catherine Jardine, Andrew R Bodenham, Prashast Prashast, James O'Rourke, Clare Mellis, Fang Gao, Craig Morris, Neil Young, Steven Henderson, Victoria Waugh, Christopher Danbury, Yongyan Qui, Georgina Parsons, Catherine Leonard, Neil Smith, Timothy Gould, Molly Chibvuri, Nicola Jacques, Sinead Helyar, Matthew Thomas, Sarah Casboult, Lukas Pokorny, Alan Davidson, Naomi Hickey, Rachael Bennett, Joanne Thompson, Orla O'Neill, Elizabeth Lemon, Paul Johnston, Cat Yates, John Trinder, Gavin Nicol, Jacqueline Baldwin, Johannes Mellinghoff, Philip Hopkins, Julian Hull, Helena Barcraft-Barnes, Lee Poole, Fiona Bottrill, Jessica Thrush, Anissa Benchiheub, Stuart Elliot, Fiona Pollock, Lauren Cooper, Grant Price, Teresa Martin, Leona Bannon, Sian Birch, Reni Jacob, Terry Martin, Gavin D. Perkins, Geraldine Ward, Donal Ryan, Esther Price, Petra Polgarova, Agnieszka Walecka, Katie Lei, Chris Nutt, Christopher Bassford, Laura Ortiz-Ruiz de Gordoa, Irfan Chaudry, Stephen E Wright

Publikováno v: Irish Critical Care Trials Group 2018, ' Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial ', The Lancet Respiratory Medicine, vol. 6, no. 9, pp. 691-698 . https://doi.org/10.1016/S2213-2600(18)30177-2
Calfee, C, Delucchi, K, Sinha, P, Matthay, M, Hackett, J, Shankar-Hari, M, McDowell, C, G. Laffey, J, O’Kane, C & McAuley, D F 2018, ' Acute respiratory distress syndrome subphenotypes and differential response to simvastatin : Secondary Analysis of a Randomized Controlled Trial ', The lancet. Respiratory medicine . https://doi.org/10.1016/S2213-2600(18)30177-2

Background: Precision medicine approaches targeting patients based on disease subtype have transformed approaches to cancer, asthma, and other heterogeneous syndromes. Two distinct subphenotypes of ARDS have been identified in three US-based clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383abcee6e51fb6ddb26ecb8bba26152
https://pure.qub.ac.uk/en/publications/acute-respiratory-distress-syndrome-subphenotypes-and-differential-response-to-simvastatin-secondary-analysis-of-a-randomised-controlled-trial(a0bb28cb-71b1-4ff0-b64d-387bd1418815).html

Three-dimension efflux velocity characteristics of marine propeller jets

Autor: Donal Ryan, Charmaine Kee, Gerard Hamill

Publikováno v: Proceedings of the Institution of Civil Engineers - Maritime Engineering. 168:62-75

Determining the efflux velocity in a ship's propeller jet is the key to calculating the velocity at any other location within the diffusing jet. Current semi-empirical equations used to calculate the magnitude of the efflux velocity have been based o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e880053bd22ae7748e0771f926a5fdc
https://doi.org/10.1680/jmaen.14.00019