Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Donal O'Carroll"'
Autor:
Therese Andersson, Sabhi Rahman, Stephen N Sansom, Jessica M Alsiö, Masahiro Kaneda, James Smith, Donal O'Carroll, Alexander Tarakhovsky, Frederick J Livesey
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13453 (2010)
To investigate the functions of Dicer and microRNAs in neural stem (NS) cell self-renewal and neurogenesis, we established neural stem cell lines from the embryonic mouse Dicer-null cerebral cortex, producing neural stem cell lines that lacked all mi
Externí odkaz:
https://doaj.org/article/3a56cd386e65468bb48c5eae610ec0ef
Autor:
Katsuhiko Hayashi, Susana M Chuva de Sousa Lopes, Masahiro Kaneda, Fuchou Tang, Petra Hajkova, Kaiqin Lao, Donal O'Carroll, Partha P Das, Alexander Tarakhovsky, Eric A Miska, M Azim Surani
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1738 (2008)
MicroRNAs (miRNAs) are critical regulators of transcriptional and post-transcriptional gene silencing, which are involved in multiple developmental processes in many organisms. Apart from miRNAs, mouse germ cells express another type of small RNA, pi
Externí odkaz:
https://doaj.org/article/4f7156a2b7a54ca091906d11f8333c33
Autor:
Birgit Stallmeyer, Clara Bühlmann, Rytis Stakaitis, Ann-Kristin Dicke, Farah Ghieh, Luisa Meier, Ansgar Zoch, David MacKenzie MacLeod, Johanna Steingröver, Özlem Okutman, Daniela Fietz, Adrian Pilatz, Antoni Riera-Escamilla, Miguel J. Xavier, Christian Ruckert, Sara Di Persio, Nina Neuhaus, Ali Sami Gurbuz, Ahmet Şalvarci, Nicolas Le May, Kevin McEleny, Corinna Friedrich, Godfried van der Heijden, Margot J. Wyrwoll, Sabine Kliesch, Joris A. Veltman, Csilla Krausz, Stéphane Viville, Donald F. Conrad, Dónal O’Carroll, Frank Tüttelmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract piRNAs are crucial for transposon silencing, germ cell maturation, and fertility in male mice. Here, we report on the genetic landscape of piRNA dysfunction in humans and present 39 infertile men carrying biallelic variants in 14 different p
Externí odkaz:
https://doaj.org/article/f298226160c54693a03e5498d577cfea
Autor:
Corey Fyfe, Gabriella Fiorentino, Michael J. Steinbaugh, Joana Campos, Hannah Lawson, Jozef Durko, Donal O'Carroll, Kamil Kranc, Darren Harvey, Shomir Ghosh, Robert M. Campbell
Publikováno v:
Cancer Research. 83:447-447
The terminal uridyltransferases TUT4/7 (ZCCHC11/6) are important mediators of RNA stability, RNA decay, histone mRNA regulation, viral RNA sensing, and miRNA biogenesis. Regulation of RNA processing pathways can be mediated by a number of RNA-binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d086023c510709a47c30fee7e9ab052
https://doi.org/10.1158/1538-7445.am2023-447
https://doi.org/10.1158/1538-7445.am2023-447
Autor:
Christopher Mapperley, Hannah Lawson, Yuka Kabayama, Elise Georges, Ali Azar, Louie Van der Lagemaat, Jasmin Paris, Marcos Morgan, Douglas Vernimmen, Donal O'Carroll, Kamil Kranc
Publikováno v:
Experimental Hematology. 111:S49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd37fb59c9e733cf3789c98cccbd2bc0
https://doi.org/10.1016/j.exphem.2022.07.065
https://doi.org/10.1016/j.exphem.2022.07.065
Autor:
Amelie V, Guitart, Theano I, Panagopoulou, Arnaud, Villacreces, Milica, Vukovic, Catarina, Sepulveda, Lewis, Allen, Roderick N, Carter, Louie N, van de Lagemaat, Marcos, Morgan, Peter, Giles, Zuzanna, Sas, Marta Vila, Gonzalez, Hannah, Lawson, Jasmin, Paris, Joy, Edwards-Hicks, Katrin, Schaak, Chithra, Subramani, Deniz, Gezer, Alejandro, Armesilla-Diaz, Jimi, Wills, Aaron, Easterbrook, David, Coman, Chi Wai Eric, So, Donal, O'Carroll, Douglas, Vernimmen, Neil P, Rodrigues, Patrick J, Pollard, Nicholas M, Morton, Andrew, Finch, Kamil R, Kranc
Publikováno v:
Guitart, A V, Panagopoulou, T I, Villacreces, A, Vukovic, M, Sepulveda, C, Allen, L, Carter, R N, van de Lagemaat, L N, Morgan, M, Giles, P, Sas, Z, Gonzalez, M V, Lawson, H, Paris, J, Edwards-Hicks, J, Schaak, K, Subramani, C, Gezer, D, Armesilla-Diaz, A, Wills, J, Easterbrook, A, Coman, D, So, C W E, O'Carroll, D, Vernimmen, D, Rodrigues, N P, Pollard, P J, Morton, N M, Finch, A & Kranc, K R 2017, ' Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions ', The Journal of experimental medicine, vol. 214, no. 3, pp. 719-735 . https://doi.org/10.1084/jem.20161087
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Guitart et al. performed an in vivo genetic dissection of the Krebs cycle enzyme fumarate hydratase (Fh1) in the hematopoietic system. Their investigations revealed multifaceted functions of Fh1 in the regulation of hematopoietic stem cell biology an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b414ecb67ecfd079f28382a9e58a2a5b
https://kclpure.kcl.ac.uk/en/publications/606e0f65-93b1-4f5f-9846-41292a145066
https://kclpure.kcl.ac.uk/en/publications/606e0f65-93b1-4f5f-9846-41292a145066
Autor:
Sudhir G. Tattikota, Thomas Rathjen, Sarah J. McAnulty, Hans-Hermann Wessels, Ildem Akerman, Martijn van de Bunt, Jean Hausser, Jonathan L.S. Esguerra, Anne Musahl, Amit K. Pandey, Xintian You, Wei Chen, Pedro L. Herrera, Paul R. Johnson, Donal O’Carroll, Lena Eliasson, Mihaela Zavolan, Anna L. Gloyn, Jorge Ferrer, Ruby Shalom-Feuerstein, Daniel Aberdam, Matthew N. Poy
Publikováno v:
Cell Metabolism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=erc_________::da74ac516fa6dea9f6a0fd6eba2fd54d
Autor:
Theresa Schöpp, Ansgar Zoch, Rebecca V. Berrens, Tania Auchynnikava, Yuka Kabayama, Lina Vasiliauskaitė, Juri Rappsilber, Robin C. Allshire, Dónal O’Carroll
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
The PIWI protein MIWI2 counteracts transposon activity by transcriptional silencing in the mammalian germline. Here, the authors show that TEX15 interacts with MIWI2 and is required for piRNA-directed methylation of transposable elements in male germ
Externí odkaz:
https://doaj.org/article/bac7f2c5d49b420186c693051a386765
Autor:
Donal O’Carroll
Publikováno v:
Conquest and Resistance ISBN: 9789004476554
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c34c2c8b47d15dc731d5168b4ffce58f
https://doi.org/10.1163/9789004476554_009
https://doi.org/10.1163/9789004476554_009