The effect of 60 days of 6° head-down-tilt bed rest on circulating adropin, irisin, retinol binding protein-4 (RBP4) and individual metabolic responses in young, healthy males

Autor: Kiera Ward, Edwin Mulder, Petra Frings-Meuthen, Donal J. O’Gorman, Diane Cooper

Publikováno v: Frontiers in Physiology, Vol 15 (2024)

BackgroundAlterations in the circulating concentrations and target-tissue action of organokines underpin the development of insulin resistance in microgravity and gravity deprivation. The purpose of this study was to examine changes in circulating ad

Externí odkaz: https://doaj.org/article/4533cd92df984bb5a8780c706a1d29f0

Time course analysis reveals gene-specific transcript and protein kinetics of adaptation to short-term aerobic exercise training in human skeletal muscle.

Autor: Brendan Egan, Paul L O'Connor, Juleen R Zierath, Donal J O'Gorman

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e74098 (2013)

Repeated bouts of episodic myofibrillar contraction associated with exercise training are potent stimuli for physiological adaptation. However, the time course of adaptation and the continuity between alterations in mRNA expression and protein conten

Externí odkaz: https://doaj.org/article/d53adf41ddcb41789f771671cf7c3b6d

Decreased expression of mitochondrial aminoacyl-tRNA synthetases causes downregulation of OXPHOS subunits in type 2 diabetic muscle

Autor: Iliana López-Soldado, Adrian Gabriel Torres, Raúl Ventura, Inma Martínez-Ruiz, Angels Díaz-Ramos, Evarist Planet, Diane Cooper, Agnieszka Pazderska, Krzysztof Wanic, Declan O'Hanlon, Donal J. O'Gorman, Teresa Carbonell, Lluís Ribas de Pouplana, John J. Nolan, Antonio Zorzano, María Isabel Hernández-Alvarez

Publikováno v: Redox Biology, Vol 61, Iss , Pp 102630- (2023)

Type 2 diabetes mellitus (T2D) affects millions of people worldwide and is one of the leading causes of morbidity and mortality. The skeletal muscle (SKM) is one of the most important tissues involved in maintaining glucose homeostasis and substrate

Externí odkaz: https://doaj.org/article/c53b67421abe4c1cbd8be5c09028244b

Fetuin-A as a Potential Biomarker of Metabolic Variability Following 60 Days of Bed Rest

Autor: Kiera Ward, Edwin Mulder, Petra Frings-Meuthen, Donal J. O’Gorman, Diane Cooper

Publikováno v: Frontiers in Physiology, Vol 11 (2020)

Background: Fetuin-A is a hepatokine linked to the development of insulin resistance. The purpose of this study was to determine if 60 days head-down-tilt (HDT) bed rest increased circulating fetuin-A and if it was linked to whole body insulin sensit

Externí odkaz: https://doaj.org/article/9c472158010f4b849e03d866df7fe8cf

Associations of Total Legume, Pulse, and Soy Consumption with Incident Type 2 Diabetes

Autor: Nita G. Forouhi, Joline W.J. Beulens, Jihye Kim, Reza Malekzadeh, Tom R.P. Bishop, Grainne O'Donoghue, Maria del Carmen Bisi Molina, Paul Knekt, Stefan Dietrich, Tommi Härkänen, Maira Bes-Rastrollo, Matthew Pearce, Hye Won Woo, Scheine Canhada, Camille Lassale, Miguel Ángel Martínez-González, Sabita S. Soedamah-Muthu, Mi Kyung Kim, Daan Kromhout, Maryam Hashemian, Adrian Cortés-Valencia, Liisa Byberg, Yeonjung Kim, Dalia Stern, Ruy Lopez Ridaura, Jonathan E. Shaw, Zhengming Chen, Donal J. O’Gorman, Dianna J. Magliano, Nicholas J. Wareham, Pedro Marques-Vidal, Bruce Bartholow Duncan, Huaidong Du, Fumiaki Imamura, Stephen J. Sharp, Alicja Wolk, Anouar Fanidi, Tasnime N. Akbaraly

Publikováno v: The Journal of nutrition, vol. 151, no. 5, pp. 1231-1240
The Journal of Nutrition, 151(5), 1231-1240. Oxford University Press
Journal of Nutrition, 151(5), 1231-1240. American Society for Nutrition
Pearce, M, Fanidi, A, Bishop, T R P, Sharp, S J, Imamura, F, Dietrich, S, Akbaraly, T, Bes-Rastrollo, M, Beulens, J W J, Byberg, L, Canhada, S, Molina, M D C B, Chen, Z, Cortes-Valencia, A, Du, H, Duncan, B B, Härkänen, T, Hashemian, M, Kim, J, Kim, M K, Kim, Y, Knekt, P, Kromhout, D, Lassale, C, Ridaura, R L, Magliano, D J, Malekzadeh, R, Marques-Vidal, P, Martínez-González, M Á, O'donoghue, G, O'gorman, D, Shaw, J E, Soedamah-Muthu, S S, Stern, D, Wolk, A, Woo, H W, Wareham, N J & Forouhi, N G 2021, ' Associations of Total Legume, Pulse, and Soy Consumption with Incident Type 2 Diabetes : Federated Meta-Analysis of 27 Studies from Diverse World Regions ', Journal of Nutrition, vol. 151, no. 5, pp. 1231-1240 . https://doi.org/10.1093/jn/nxaa447
The Journal of Nutrition, 151(5), 1231-1240. American Society for Nutrition
The Journal of Nutrition
Journal of Nutrition

Background: The consumption of legumes is promoted as part of a healthy diet in many countries but associations of total and types of legume consumption with type 2 diabetes (T2D) are not well established. Analyses across diverse populations are lack

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fd5088254912eb2d45969811af39df
https://doi.org/10.1093/jn/nxaa447