Zobrazeno 1 - 10 of 69 pro vyhledávání: '"Donal B. Murphy"'
2
Self-Restricted Dual Receptor Memory T Cells
Autor: William T. Lee, Vaibhavi Shiledar-Baxi, Gary M. Winslow, Denise Mix, Donal B. Murphy
Publikováno v: The Journal of Immunology. 161:4513-4519
Enhanced immune responses during secondary exposure to Ag result from the development of memory cells. In the present report we show that stimulation through one receptor on dual receptor CD4 cells can promote the generation of T cells capable of giv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c29c9c0721ef2e8daed16c20469da824
https://doi.org/10.4049/jimmunol.161.9.4513
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3
Multiple sites of crossing over within the Eb recombinational hotspot in the mouse
Autor: Joseph A. DePari, Derek B. Sant'Angelo, Elizabeth C. Bryda, Donal B. Murphy, Howard C. Passmore
Publikováno v: Mammalian Genome. 2:123-129
The Eb gene of the mouse major histocompatibility complex (MHC) contains a well-documented hotspot of recombination. Twelve cases of intra-Eb recombination derived from the b, d, k and s alleles of the Eb gene were sequenced to more precisely positio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bf8ecae101846f2fe231311b571914
https://doi.org/10.1007/bf00353860
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4
Recognition of the product of a novel MHC TL region gene (27b) by a mouse γδ T cell receptor
Autor: Sang Hsu, Kouichi Ito, Luc Van Kaer, Donal B. Murphy, Marc Bonneville, Susumu Tonegawa
Publikováno v: Cell. 62:549-561
The gamma delta T cell receptor (TCR) derived from the mouse KN6 T cell hybridoma recognizes an autologous determinant encoded by a broadly expressed gene mapping in the TL region of the major histocompatibility complex (MHC). We have cloned the gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a56715a6f8cf01c128d80e8f0c34ca
https://doi.org/10.1016/0092-8674(90)90019-b
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7
On the complexity of self
Autor: Satyajit Rath, Donal B. Murphy, Alexander Y. Rudensky, Paula Preston-Hurlburt, Charles A. Janeway
Publikováno v: Nature. 353:660-662
SELF peptides bound to self major histocompatibility complex (MHC) molecules have been implicated both in positive1,2 and in negative3,4 selection of T cells during intrathymic development. We report here that the novel MHC-restricted monoclonal anti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::006b5dea1e966eb3ceda4c4e89d667d1
https://doi.org/10.1038/353660a0
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8
T cell mediated immunosuppression
Autor: Donal B. Murphy
Publikováno v: Current opinion in immunology. 5(3)
Suppressor T cells down-regulate the activity of other cells in the immune system, and, albeit controversial, are believed to play a role in immunological tolerance and immunoregulation. Significant progress has been made in characterizing suppressor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f89c2fc4f43c287afc484b6ee44722fa
https://pubmed.ncbi.nlm.nih.gov/8347300
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9
Rules for the Presentation of Peptides by Class II Molecules of the Major Histocompatibility Complex
Autor: J. Rothbard, E.-P. Reich, Basel K. al-Ramadi, Donal B. Murphy, Alexander Y. Rudensky, C. A. JanewayJr., Paula Preston-Hurlburt
Publikováno v: Progress in Immunology Vol. VIII ISBN: 9783642514814
As virtually all adaptive immune responses involve the activation of CD4 T cells by specific antigen, a central question in immunology is the nature of the ligands recognized by these cells. It is now well established that CD4 T cells respond to pept
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2338dce6800514550b9cfc484818c98
https://doi.org/10.1007/978-3-642-51479-1_24
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