Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Don-Gerard Conde"'
Autor:
Tao Yu, Dan Hou, Jiaqi Zhao, Xuan Lu, Wendy K. Greentree, Qian Zhao, Min Yang, Don-Gerard Conde, Maurine E. Linder, Hening Lin
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114070- (2024)
Summary: Nucleotide oligomerization domain (NOD)-like receptor protein 3 (NLRP3) inflammasome hyperactivation contributes to many human chronic inflammatory diseases, and understanding how NLRP3 inflammasome is regulated can provide strategies to tre
Externí odkaz:
https://doaj.org/article/364166cdf5514bd08b0ded6877667215
Autor:
George K. Annor, Nour Elshabassy, Devon Lundine, Don-Gerard Conde, Gu Xiao, Viola Ellison, Jill Bargonetti
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The TP53 gene is often mutated in cancer, with missense mutations found in the central DNA binding domain, and less often in the C-terminal oligomerization domain (OD). These types of mutations are found in patients with the rare inherited cancer pre
Externí odkaz:
https://doaj.org/article/43c728f37129456c94c03c1a6bf4997b
Autor:
Mohammad Faujul Kabir, Jazmyne L Jackson, Annie D Fuller, Leonny Gathuka, Adam L Karami, Don-Gerard Conde, Alena Klochkova, Anbin Mu, Kathy Q Cai, Andres J Klein-Szanto, Amanda B Muir, Kelly A Whelan
Publikováno v:
Carcinogenesis. 44:182-195
Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive forms of human malignancy, often displaying limited therapeutic response. Here, we examine the non-steroidal anti-inflammatory drug diclofenac (DCF) as a novel therapeutic agent