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A Prospective Randomized Controlled Trial of Structured Treatment Interruption in HIV-Infected Patients Failing Highly Active Antiretroviral Therapy (Canadian HIV Trials Network Study 164)

Autor: Richard Harrigan, Sharon Walmsley, Don Zarowny, Natasha LaPierre, John Macleod, Anona Thorne, Benoit Trottier, Joy R Hay, Brian Conway, Mona Loutfy, Joel Singer

Publikováno v: JAIDS Journal of Acquired Immune Deficiency Syndromes. 45:418-425

Objective: To determine prospectively the impact of switching treatment-experienced patients with virologic failure to a salvage regimen with or without a 12-week structured treatment interruption (STI). The primary endpoint was the percentage of pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc162107ebd0934ac7838b57e48c6d5
https://doi.org/10.1097/qai.0b013e318061b611

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Longitudinal changes in HIV-specific IFN-γ secretion in subjects who received Remune™ vaccination prior to treatment interruption

Autor: Nicole F. Bernard, Famane Chung, Maude Loignon, Don Zarowny, Marie-Pierre Boisvert, Emil Toma, Kenneth H Huang, Lise Cyr

Publikováno v: Journal of Immune Based Therapies and Vaccines

BACKGROUND:Despite the benefits of highly active antitretroviral therapy (HAART) for suppressing viral replication in HIV infection, virus persists and rebounds during treatment interruption (TI). This study explored whether HAART intensification wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fec9e9499d1e16b77e96b4473cc6729
https://doi.org/10.1186/1476-8518-4-7

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