Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Don W. Walker"'
Publikováno v:
Synapse. 48:189-197
Human alcoholics and animals that have received chronic ethanol treatment (CET) display memory deficits. Previous work in our laboratory has shown that CET produces damage to the hippocampus and a reduction in the magnitude of hippocampal long-term s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7012c044a68dc2d94a99a21245973742
https://doi.org/10.1002/syn.10203
https://doi.org/10.1002/syn.10203
Publikováno v:
Journal of Neurochemistry. 81:853-858
Primary hippocampal neuronal cultures exhibited a concentration- and time-dependent loss of cells when exposed to ethanol (EtOH). EtOH-induced neurotoxicity was attenuated by 2,4-dimethoxybenzilidene anabaseine (DMXB) which selectively activates alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea6982b952c2e66f163eb5866825fd15
https://doi.org/10.1046/j.1471-4159.2002.00891.x
https://doi.org/10.1046/j.1471-4159.2002.00891.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 26:695-704
Introduction: Females experience greater liver damage, have reduced brain size, and have greater memory deficits than do males with a similar history of alcoholism. Females have higher peak alcohol levels and faster elimination rates than males. Our
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caa7b002d21e9becf3760d5dd34008c7
https://doi.org/10.1111/j.1530-0277.2002.tb02593.x
https://doi.org/10.1111/j.1530-0277.2002.tb02593.x
Publikováno v:
Free Radical Biology and Medicine. 30:389-392
Pheochromocytoma (PC12) cell cultures exhibited a loss of cells and increase in intracellular oxidative stress when exposed to ethanol (EtOH) for 24 h. Catalase, an enzyme that hydrolyzes hydrogen peroxide (H(2)O(2)) to O(2) and H(2)O can attenuate E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f540ee212c5f7ec4923c89a463a073
https://doi.org/10.1016/s0891-5849(00)00484-6
https://doi.org/10.1016/s0891-5849(00)00484-6
Publikováno v:
Developmental Brain Research. 121:97-107
Neonatal rats were exposed to ethanol throughout gestation, or during the early postnatal period (postnatal days 4–10 (P4–10)), and enzyme-linked immunoabsorbent assays were subsequently conducted in order to assess nerve growth factor (NGF), bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158123ae7be0009cf4c8b835db1656bb
https://doi.org/10.1016/s0165-3806(00)00032-8
https://doi.org/10.1016/s0165-3806(00)00032-8
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:1587-1595
Background: Chronic ethanol treatmcnt (CET) for 28 weeks significantly increases electrically-stimulated 3H-GABA release from hippocampal slices. This increase in GABA release may be one of the mechanisms by which CET decreases the magnitude of long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d5b9a37fff2079a4edd2901ee9d097
https://doi.org/10.1111/j.1530-0277.1999.tb04048.x
https://doi.org/10.1111/j.1530-0277.1999.tb04048.x
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:1251-1261
Background: The objective of the present work was to determine whether ethanol-induced cerebellar cell death during development is related to alterations in the expression of bcl-2 family genes. Methods: Rats were exposed to ethanol or control condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6377cd8d6ae79e8f4ef809aa23b739ca
https://doi.org/10.1111/j.1530-0277.1999.tb04286.x
https://doi.org/10.1111/j.1530-0277.1999.tb04286.x
Publikováno v:
Alcohol. 15:219-226
The objective of this study was to determine the long-term effects of neonatal ethanol exposure on the cholinergic neurons in the medial septum (MS) of the rat. On postnatal day 4 (P4) pups were assigned to one of three groups: an ethanol-receiving,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614a2358636ad3cea482d784f13baa74
https://doi.org/10.1016/s0741-8329(97)00123-7
https://doi.org/10.1016/s0741-8329(97)00123-7
Publikováno v:
Brain Research. 778:354-366
Ethanol exposure affects cellular mechanisms involved in the regulation of calcium (Ca2+) homeostasis. Neurotrophins, such as nerve growth factor (NGF), stabilize intracellular Ca2+([Ca2+]i) during a variety of neurotoxic insults. In this study, chan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c174ab0ae27039e257800fd9ab735f
https://doi.org/10.1016/s0006-8993(97)01088-3
https://doi.org/10.1016/s0006-8993(97)01088-3
Publikováno v:
Alcoholism: Clinical and Experimental Research. 21:1643-1652
The neurotoxic effect of acute ethanol treatment (AET) may lead to an alteration in the regulation of calcium (Ca 2+ ) homeostasis in hippocampal neurons. Ca 2+ homeostasis could be affected by AET when neurons are at rest or after depolarizing activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91084bc1538fe32d3cb9769ea1bfd701
https://doi.org/10.1111/j.1530-0277.1997.tb04502.x
https://doi.org/10.1111/j.1530-0277.1997.tb04502.x