Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Don W Powell"'
Autor:
Yanbo Tang, Kevin T Kline, Xiaoying S Zhong, Ying Xiao, Haifeng Lian, Jun Peng, Xiaowei Liu, Don W Powell, Guodu Tang, Qingjie Li
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257280 (2021)
Ulcerative colitis and Crohn's disease are classified as chronic inflammatory bowel diseases (IBD) with known extraintestinal manifestations. The interplay between heart and gut in IBD has previously been noted, but the mechanisms remain elusive. Our
Externí odkaz:
https://doaj.org/article/4ed7c329efcb417b875c3d91722f200a
Autor:
Haifeng Lian, Xiaoying S. Zhong, Ying Xiao, Zhe Sun, Yuanyuan Shen, Kaile Zhao, Xingbin Ma, Yanmin Li, Qiong Niu, Max Liu, Don W. Powell, Chengxia Liu, Qingjie Li
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Background and Aims: While the interplay between heart and gut in inflammatory bowel disease (IBD) has previously been noted, how the inflamed gut impairs heart function remain elusive. We hypothesized that exosomal miRNAs of gut origin induce cardia
Externí odkaz:
https://doaj.org/article/c591b5a96d784c058c6c8caa7ebe1969
Publikováno v:
Oncotarget. 14:377-381
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a788521bcec3e562bf51ed2cddf4f9f3
https://doi.org/10.18632/oncotarget.28399
https://doi.org/10.18632/oncotarget.28399
Autor:
Romain Villéger, Marina Chulkina, Randy C. Mifflin, Nikolay S. Markov, Judy Trieu, Mala Sinha, Paul Johnson, Jamal I. Saada, Patrick A. Adegboyega, Bruce A. Luxon, Ellen J. Beswick, Don W. Powell, Irina V. Pinchuk
Publikováno v:
British Journal of Cancer. 128:537-548
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f9988e6c95e7f2d46d531d854ddf6b4
https://doi.org/10.1038/s41416-022-02066-0
https://doi.org/10.1038/s41416-022-02066-0
Autor:
Jia Wang, Ruwen Cui, Cecila G. Clement, Ranjana Nawgiri, Don W. Powell, Irina V. Pinchuk, Tammara L. Watts
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Desmoplasia, a hallmark of a head and neck cancer, has both biologic and physiologic effects on cancer progression and chemotherapeutic response. Mesenchymal stem/stromal cells (MSCs), also known as mesenchymal stromal progenitor cells, have been sho
Externí odkaz:
https://doaj.org/article/92d11a8b70f64a7c93915ceac3a354fd
Autor:
Xiaoying S. Zhong, John H. Winston, Xiuju Luo, Kevin T. Kline, Syed Z. Nayeem, Yingzi Cong, Tor C. Savidge, Roderick H. Dashwood, Don W. Powell, Qingjie Li
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 1, Pp 65-78 (2018)
Early life adversity is considered a risk factor for the development of gastrointestinal diseases, including inflammatory bowel disease. We hypothesized that early life colonic inflammation causes susceptibility to aggravated overexpression of interl
Externí odkaz:
https://doaj.org/article/b3e399dbf4df4c328cf6dd613953469f
Autor:
Ellen J. Beswick, Carl Grim, Abinav Singh, Jose E. Aguirre, Marissa Tafoya, Suimin Qiu, Gerhard Rogler, Rohini McKee, Von Samedi, Thomas Y. Ma, Victor E. Reyes, Don W. Powell, Irina V. Pinchuk
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background and AimsThe role of programmed cell death protein 1 (PD-1) and its ligands in the dysregulation of T helper immune responses observed in the inflammatory bowel disease (IBD) is unclear. Recently, a novel concept emerged that CD90+ colonic
Externí odkaz:
https://doaj.org/article/72f3d5fe09324db49b2672bbbb807344
Autor:
Don W, Powell
Publikováno v:
Southern Medical Journal. 115:35-37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c07ac06ba51ab7654d994496d44872
https://doi.org/10.14423/smj.0000000000001347
https://doi.org/10.14423/smj.0000000000001347
Autor:
Ying Xiao, Haifeng Lian, Xiaoying S. Zhong, Srikruthi S. Krishnachaitanya, Yingzi Cong, Roderick H. Dashwood, Tor C. Savidge, Don W. Powell, Xiaowei Liu, Qingjie Li
Publikováno v:
Frontiers in immunology. 13
BackgroundPrevious studies implicated matrix metalloproteinases (MMPs), such as MMP-7, in inflammatory bowel diseases (IBD) by showing increased activity during inflammation of the gut. However, the pathophysiological roles of MMP-7 have not been cle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdab82635a77c19e038d847e8e8ff25
https://pubmed.ncbi.nlm.nih.gov/36275703
https://pubmed.ncbi.nlm.nih.gov/36275703
Autor:
Yuriy Fofanov, Paul Johnson, Tammara L Watts, Don W. Powell, Walter A. Koltun, Gabriela Uribe, Kamil Khanipov, Carl Grim, Gregory S Yochum, Irina V. Pinchuk, Ellen J Beswick, Robert Noble
Publikováno v:
J Crohns Colitis
Background and AimsLittle is known about the presence and function of tissue-resident mesenchymal stem cells [MtSCs] within the gastrointestinal mucosa in health and inflammatory bowel disease [IBD]. The contribution of MtSCs to the generation of inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c87f141e1c80d3e2512c329c7e233c4
https://doi.org/10.1093/ecco-jcc/jjab001
https://doi.org/10.1093/ecco-jcc/jjab001