Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Don Slaughter"'
Autor:
Edward Keough, Suzie Yeh, Mike Lyman, Ken Koeplinger, Ed Carlini, Charles D. Thompson, Jeff Roberts, Marian E. Gindy, Melissa Stern, Scott Fauty, Mei Ou, Yan Xu, Elizabeth Mahan, Conrad E. Raab, Yi Wang, Jerome Hochman, Rena Zhang, Don Slaughter
Publikováno v:
Molecular Pharmaceutics. 11:1424-1434
Effective delivery of small interfering RNA (siRNA) requires efficient cellular uptake and release into cytosol where it forms an active complex with RNAi induced silencing complex (RISC). Despite rapid developments in RNAi therapeutics, improvements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9336458e9196c53535274f85ff505c96
https://doi.org/10.1021/mp400584h
https://doi.org/10.1021/mp400584h
Publikováno v:
Metabolic Engineering. 2:115-125
In this communication, we report that suspension cultures of Sf21 insect cells, co-infected with baculovirus containing the cDNA for a single cytochrome P450 and NADPH-cytochrome P450 oxidoreductase, can be employed successfully as "bioreactors" for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131a2ed4bd54519837de924b2dde3567
https://doi.org/10.1006/mben.2000.0147
https://doi.org/10.1006/mben.2000.0147
Publikováno v:
The Journal of urology. 57(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485a9c829149b8045c056f09ab8f6af4
https://pubmed.ncbi.nlm.nih.gov/20243929
https://pubmed.ncbi.nlm.nih.gov/20243929
Autor:
Peter J. O'Brien, Don Slaughter
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 883:225-232
The horseradish peroxidase/hydrogen peroxide-supported oxidation of N , N -dimethylaniline is shown to proceed along three separate primary pathways; N -demethylation to N -metnylaniline, dimerization to N , N , N ′, N ′-tetramethyl- p , p ′-be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56f3e05351becbb57b8a07c54c804c73
https://doi.org/10.1016/0304-4165(86)90312-0
https://doi.org/10.1016/0304-4165(86)90312-0
Publikováno v:
Journal of Biological Chemistry. 256:2022-2026
The antifreeze proteins of the sea raven, Hemitripterus americanus, were isolated and compared with other fish antifreeze proteins. The sea raven contains one major protein of molecular weight 14,000-16,000 with little or no carbohydrate. Except for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1177af1831e0bec8ebec901172e2edf9
https://doi.org/10.1016/s0021-9258(19)69910-2
https://doi.org/10.1016/s0021-9258(19)69910-2
Publikováno v:
Canadian Journal of Zoology. 60:1851-1854
A seasonal study was carried out on the hematocrits, plasma freezing point depression, and thermal hysteresis, and plasma Na+, Cl−, total protein, and glucose concentrations in laboratory maintained Atlantic cod. Significant thermal hysteresis was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5330e380329bcb7ff10cb3bff3fa0f4f
https://doi.org/10.1139/z82-240
https://doi.org/10.1139/z82-240
Autor:
Choy L. Hew, Don Slaughter
Publikováno v:
Analytical Biochemistry. 115:212-218
An improved procedure for the determination of antifreeze protein activity using a freezing point osmometer is described. The method incorporates the use of plastic, air-jacketed osmometer tubes, silver iodide as an ice nucleating agent, and the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071750997466cf7ef8ed36b0f022fede
https://doi.org/10.1016/0003-2697(81)90548-0
https://doi.org/10.1016/0003-2697(81)90548-0
Publikováno v:
Canadian Journal of Zoology. 59:2186-2192
The plasma of the Atlantic cod, Gadus morhua, contained antifreeze glycoproteins which were present only during the winter months. The antifreeze proteins were isolated, using gel filtration and ion exchange chromatography, and characterized by high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9806a98428523af24f0e270db9aedc72
https://doi.org/10.1139/z81-296
https://doi.org/10.1139/z81-296
Autor:
Don Slaughter, Choy L. Hew
Publikováno v:
Canadian Journal of Biochemistry. 60:824-829
The polymerization of winter flounder antifreeze polypeptide (AFP) with glutaraldehyde to increase its antigenicity and the conjugation of the AFP to bovine serum albumin so that the AFP could carry a radioiodine label have allowed the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d12a8c3ba2c091d8a44683f95d2b31
https://doi.org/10.1139/o82-103
https://doi.org/10.1139/o82-103
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 870:154-159
CD spectral data on the antifreeze proteins from the ocean pout ( Macrozoarces americanus ) have been obtained under native and denaturing conditions. At low temperatures (near 0°C), the far-ultraviolet CD spectra of the two known immunologically di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e548da1fd17198db68e4bc630ad441
https://doi.org/10.1016/0167-4838(86)90019-1
https://doi.org/10.1016/0167-4838(86)90019-1