Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Don S. Richards"'
Autor:
J. Richard Joyce, Don S. Richards
Publikováno v:
Journal of the American Society for Mass Spectrometry. 22:360-368
The site of protonation in a molecule can greatly affect the fragments observed in product ion MS/MS spectra. In electrospray positive ionization mass spectra, protonation usually occurs predominantly on the most basic site on the molecule to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47dd51be7ce21ea97eca0112e91f6482
https://doi.org/10.1007/s13361-010-0037-0
https://doi.org/10.1007/s13361-010-0037-0
Publikováno v:
Rapid Communications in Mass Spectrometry. 24:1665-1672
Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry Imaging (MALDI MSI) has been used to directly analyse a range of tablets in order to assess the homogeneity of the active drug compound throughout the excipients contained within the table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64151c71b85ca2086b559402c372a50f
https://doi.org/10.1002/rcm.4525
https://doi.org/10.1002/rcm.4525
Publikováno v:
International Journal of Mass Spectrometry. :60-67
Head-space analysis at high mass resolution has been carried out of volatile compounds emanating from each of six species of truffle so as to identify those compounds that reveal to dogs, pigs, and flies (genus Suillia) the truffle's subterranean hab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b8e1a2704e47480600c1e8ebcdf619
https://doi.org/10.1016/j.ijms.2005.12.038
https://doi.org/10.1016/j.ijms.2005.12.038
Autor:
Louisa N. Alfazema, John C. Mitchell, Don S. Richards, Martin J. Snowden, Sylvie Sylvie Gélébart
Publikováno v:
European Journal of Mass Spectrometry. 11:393-402
We have developed a liquid chromatography tandem mass spectrometry (LC-MS/MS) system capable of achieving better than 2% accuracy, routinely over a wide concentration range of 1–800 ng mL−1. We demonstrate that the necessary high precision, high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8572af103a059c66d5c4053da2d5bd
https://doi.org/10.1255/ejms.772
https://doi.org/10.1255/ejms.772
Publikováno v:
Rapid Communications in Mass Spectrometry. 18:3051-3060
Matrix-assisted laser desorption/ionisation (MALDI) quadrupole time-of-flight mass spectrometry (Q-TOFMS) has been used to detect and image the distribution of a xenobiotic substance in skin. Porcine epidermal tissue was treated with 'Nizoral', a med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50f34f187730d43e3b010dcffdaef1c
https://doi.org/10.1002/rcm.1725
https://doi.org/10.1002/rcm.1725
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:264-270
Thin layer chromatography/matrix-assisted laser desorption/ionisation mass spectrometry (TLC/MALDI-MS) has been previously used to obtain mass spectra from a variety of compounds, principally peptides. For pharmaceutical compounds, which are often of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3955fc0d813386290f31a3a1311defe
https://doi.org/10.1002/(sici)1097-0231(19990228)13:4<264::aid-rcm460>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19990228)13:4<264::aid-rcm460>3.0.co
Publikováno v:
Journal of Mass Spectrometry. 32:64-70
The earlier use of combined liquid chromatography/NMR spectrometry/mass spectrometry (LC/NMR/MS) involved the use of a particle beam interface. This paper describes further developments of this hyphenated technology, in particular the incorporation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a761c6ee32a62ea88dbd8e996eeecb60
https://doi.org/10.1002/(sici)1096-9888(199701)32:1<64::aid-jms450>3.0.co
https://doi.org/10.1002/(sici)1096-9888(199701)32:1<64::aid-jms450>3.0.co
Publikováno v:
Journal of Chromatography A. 746:9-15
Confirmation of chiral purity is usually carried out via HPLC separation. The mobile phases required to effect good separation, using polar organic phase chromatography on cyclodextrin columns, result in poor detection when the compounds of interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d75143b58559b5aa3b142b131f8b525
https://doi.org/10.1016/0021-9673(96)00309-3
https://doi.org/10.1016/0021-9673(96)00309-3
Publikováno v:
Rapid Communications in Mass Spectrometry. 9:1003-1006
Liquid chromatography (LC), simultaneously coupled with both nuclear magnetic resonance (NMR) and mass spectrometry (MS) ‘on-line’ is a powerful structural tool and has a potentially vast range of uses within the pharmaceutical industry. Data fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60ea52d19c172c950965dd39014c9d82
https://doi.org/10.1002/rcm.1290091106
https://doi.org/10.1002/rcm.1290091106
Autor:
David V. Brown, Frank H. Cottee, Frank S. Pullen, George L. Perkins, Don S. Richards, Melanie Dalton
Publikováno v:
Rapid Communications in Mass Spectrometry. 8:632-636
Nuclear magnetic resonance (NMR) and mass spectrometry (MS) are the major spectroscopic tools used by synthetic organic chemists to monitor the steps of their syntheses. Rapid confirmation of the structure at each synthetic step is vital for efficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f4d6b07047576e648f574fe734f657f
https://doi.org/10.1002/rcm.1290080812
https://doi.org/10.1002/rcm.1290080812