Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Don O. Kikkawa"'
Publikováno v:
Endocrinology and Metabolism, Vol 38, Iss 6, Pp 739-749 (2023)
Background Phospholipase C-γ (PLC-γ) plays a crucial role in immune responses and is related to the pathogenesis of various inflammatory disorders. In this study, we investigated the role of PLC-γ and the therapeutic effect of the PLC-specific inh
Externí odkaz:
https://doaj.org/article/d1d6633a0dff4d5280c50faac8b5ec91
Autor:
Sun Young Jang, Jinjoo Kim, Jung Tak Park, Catherine Y. Liu, Bobby S. Korn, Don O. Kikkawa, Eun Jig Lee, Jin Sook Yoon
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Periostin is a matricellular protein that is ubiquitously expressed in normal human tissues and is involved in pathologic mechanism of chronic inflammatory and fibrotic disease. In this study we investigate periostin in the pathogenesis of Graves’
Externí odkaz:
https://doaj.org/article/bf2fae0e4d4b40a28d57e73eef837a6e
Publikováno v:
PLoS ONE, Vol 17, Iss 12 (2022)
Purpose Bruton’s tyrosine kinase (BTK) is an essential protein in B-cell antigen receptor (BCR) signaling pathway and is known to be related to pathogenetic effect on B-cell related malignancies and various autoimmune diseases. In this study, we in
Externí odkaz:
https://doaj.org/article/3c1cc627035b4af081db684ae695179e
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 19, Iss , Pp 100744- (2020)
Purpose: To report the first case of a patient with chronic thyroid eye disease (TED) treated with teprotumumab. Observations: A 50-year-old female with a 3-year history of Graves’ disease presented with bilateral exophthalmos greatest on the left
Externí odkaz:
https://doaj.org/article/62393c78d07d47efb1a242499e8e6c8d
Autor:
Christine Y. Shen, Spencer Woody, Spencer D. Fuller, Landon K. Grange, Kimberly D. Tran, Jeanne G. Lee, Don O. Kikkawa, Jeffrey E. Lee
Publikováno v:
Journal of Academic Ophthalmology, Vol 12, Iss 02, Pp e87-e91 (2020)
Objective This study aims to discuss clinical characteristics of burn patients who developed elevated intraocular pressure (IOP). We propose management strategies to prevent orbital compartment syndrome before invasive treatment is required. Methods
Externí odkaz:
https://doaj.org/article/c5ff7a96262b48cabd1816691baceb7a
Autor:
Helena E. Gali, Sally L. Baxter, Lina Lander, Abigail E. Huang, Marlene Millen, Robert El-Kareh, Eric Nudleman, Daniel L. Chao, Shira L. Robbins, Christopher W.D. Heichel, Andrew S. Camp, Bobby S. Korn, Jeffrey E. Lee, Don O. Kikkawa, Christopher A. Longhurst, Michael F. Chiang, Michelle R. Hribar, Lucila Ohno-Machado
Publikováno v:
Journal of Academic Ophthalmology, Vol 11, Iss 02, Pp e65-e72 (2019)
Objective Electronic health records (EHRs) are widely adopted, but the time demands of EHR use on ophthalmology trainees are not well understood. This study evaluated ophthalmology trainee time spent on clinical activities in an outpatient clinic und
Externí odkaz:
https://doaj.org/article/68f2d3c5c9a543a6b3e06081a1dd5820
Publikováno v:
American Journal of Ophthalmology Case Reports, Vol 14, Iss , Pp 110-111 (2019)
Changes in behavioral patterns can be the only indication of the presence of pain in nonverbal patients. Phthisis bulbi results in shrinking, disorganization, and sometimes severe inflammation of the ocular globe and can occur after eye injury or mul
Externí odkaz:
https://doaj.org/article/0f7d7745ed5545e7a49ba0dbe8e9118d
Publikováno v:
Journal of Skin Cancer, Vol 2012 (2012)
Reconstruction of periocular defects following excision of cutaneous malignancy can present difficulties for oculofacial and reconstructive surgeons. The intricate anatomy of the eyelids and face requires precise restoration in order to avoid postope
Externí odkaz:
https://doaj.org/article/51ab781683b24b669294e942e81d6c5e
Autor:
Alison X, Chan, Bharanidharan, Radha Saseendrakumar, Daniel J, Ozzello, Michelle, Ting, Jin Sook, Yoon, Catherine Y, Liu, Bobby S, Korn, Don O, Kikkawa, Sally L, Baxter
Publikováno v:
Orbit (Amsterdam, Netherlands). 41(6)
To identify common factors associated with the loss of an eye using the NIH All of Us database.In this case-controlled study, we extracted electronic health record and socio-demographic data for 231 cases of eye loss from All of Us enrollment sites.
Autor:
Liane O. Dallalzadeh, Lilangi S. Ediriwickrema, Sammie E. Fung, Clara J. Men, Andrea L. Kossler, Anna C. Kupcha, Louise A. Mawn, Cat N. Burkat, Suzanne W. van Landingham, Jordan R. Conger, Brittany Simmons, Chau Pham, Sruti S. Akella, Pete Setabutr, Tiffany Ho, Steven M. Couch, Jane S. Kim, Hakan Demirci, Bobby S. Korn, Don O. Kikkawa, Catherine Y. Liu
Publikováno v:
Orbit. :1-8