Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Don L. Theis"'
Publikováno v:
Pharmaceutical Research. 11:1069-1076
Certain delivery systems are intended to release the active ingredient in different phases to obtain the desired therapeutic effect. For these formulations, such as a bilayer tablet, it is desirable to distinguish and measure the release of drug from
Publikováno v:
Journal of Chromatography A. 367:254-259
Piriprost potassium [potassium salt of 6,9-deepoxy-6,9(phenylimino)-d 6*8prostaglandin I1 (Fig. 1) is a selective inhibitor of leukotriene synthesis and is currently the subject of clinical studieslp4. An analytical method was needed to analyze bulk
Autor:
Don L. Theis, Gordon W. Halstead
Publikováno v:
Journal of Pharmaceutical Sciences. 74:1086-1090
The effects of temperature, pH, and apparatus design on in vitro drug release from a controlled-release vaginal device containing the prostaglandin, carboprost methyl, were investigated and a semi-automated drug release test was developed based on th
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 380:77-87
A capillary gas chromatographic—mass spectrometric method for the determination of ibuprofen and tetra-deuterated ibuprofen in serum is described. Ibuprofen, [ar- 2 H 4 ]-ibuprofen and the internal standard, [ar- 2 H 4 ,3,3,3- 2 H 3 ]ibuprofen, are
Publikováno v:
Journal of chromatography. 321(1)
An high-performance liquid chromatography method was developed that separates (5Z)-9 beta-methyl-6 alpha-carbaprostaglandin I2 (9 beta-methylcarbacyclin; ciprostene) from several closely related isomers: (i) a double bond isomer at C-5, (ii) an epime
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 7(5)
The effect of temperature on drug release from meteneprost potassium vaginal suppositories was investigated using a dissolution test based on the USP I apparatus. Comparison of the dissolution results with the DSC melting behaviour revealed that drug
Publikováno v:
Journal of chromatography. 375(2)
This paper describes the development of a capillary gas chromatographic—mass spectrometric method for the determination of N-[ trans -2-(dimethylamino)cyclopentyl]-N-(3′,4′-dichlorophenyl)propanamide and its metabolites in serum. The method uti
Autor:
Don L. Theis
Publikováno v:
Journal of chromatography. 402