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Autor:
Gordon J. Conard, Robert H Bergstrand, Lyle A. Siddoway, Ted Wang, Katherine A. Thompson, Don Kvam, Dan M. Roden, Raymond L. Woosley
Publikováno v:
Clinical pharmacology and therapeutics. 43(5)
A two-part pharmacokinetic approach was used to prospectively develop and test intravenous flecainide infusion regimens for the acute therapy for ventricular arrhythmias. Initially, each of nine known responders to oral flecainide was given a rapid f