Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Don Ganem"'
Autor:
Anastasia Hyrina, Christopher Jones, Darlene Chen, Scott Clarkson, Nadire Cochran, Paul Feucht, Gregory Hoffman, Alicia Lindeman, Carsten Russ, Frederic Sigoillot, Tiffany Tsang, Kyoko Uehara, Lili Xie, Don Ganem, Meghan Holdorf
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 2970-2978.e6 (2019)
Summary: A hallmark of chronic hepatitis B (CHB) virus infection is the presence of high circulating levels of non-infectious small lipid HBV surface antigen (HBsAg) vesicles. Although rare, sustained HBsAg loss is the idealized endpoint of any CHB t
Externí odkaz:
https://doaj.org/article/1de14fd71bb445e89c5fdea311bfc65e
Autor:
Carolina Arias, Ben Weisburd, Noam Stern-Ginossar, Alexandre Mercier, Alexis S Madrid, Priya Bellare, Meghan Holdorf, Jonathan S Weissman, Don Ganem
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003847 (2014)
Productive herpesvirus infection requires a profound, time-controlled remodeling of the viral transcriptome and proteome. To gain insights into the genomic architecture and gene expression control in Kaposi's sarcoma-associated herpesvirus (KSHV), we
Externí odkaz:
https://doaj.org/article/896446cc52d64ac0aa2ac2dac5b932a5
Autor:
Deanna Lee, Jaydip Das Gupta, Christina Gaughan, Imke Steffen, Ning Tang, Ka-Cheung Luk, Xiaoxing Qiu, Anatoly Urisman, Nicole Fischer, Ross Molinaro, Miranda Broz, Gerald Schochetman, Eric A Klein, Don Ganem, Joseph L Derisi, Graham Simmons, John Hackett, Robert H Silverman, Charles Y Chiu
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44954 (2012)
XMRV, or xenotropic murine leukemia virus (MLV)-related virus, is a novel gammaretrovirus originally identified in studies that analyzed tissue from prostate cancer patients in 2006 and blood from patients with chronic fatigue syndrome (CFS) in 2009.
Externí odkaz:
https://doaj.org/article/cc0eca477cbf493faa628dcd60a4f7d2
Autor:
Sanjay Chandriani, Don Ganem
Publikováno v:
PLoS ONE, Vol 2, Iss 8, p e811 (2007)
Lytic infection by Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with an extensive shutoff of host gene expression, mediated chiefly by accelerated mRNA turnover due to expression of the viral SOX protein. We have previously identified
Externí odkaz:
https://doaj.org/article/40744cab24dd4ac1872725d284bf2771
Autor:
Anatoly Urisman, Ross J Molinaro, Nicole Fischer, Sarah J Plummer, Graham Casey, Eric A Klein, Krishnamurthy Malathi, Cristina Magi-Galluzzi, Raymond R Tubbs, Don Ganem, Robert H Silverman, Joseph L DeRisi
Publikováno v:
PLoS Pathogens, Vol 2, Iss 3, p e25 (2006)
Ribonuclease L (RNase L) is an important effector of the innate antiviral response. Mutations or variants that impair function of RNase L, particularly R462Q, have been proposed as susceptibility factors for prostate cancer. Given the role of this ge
Externí odkaz:
https://doaj.org/article/fe3f8c4939fb4609b265344ee8a99a5d
Autor:
David Wang, Anatoly Urisman, Yu-Tsueng Liu, Michael Springer, Thomas G Ksiazek, Dean D Erdman, Elaine R Mardis, Matthew Hickenbotham, Vincent Magrini, James Eldred, J Phillipe Latreille, Richard K Wilson, Don Ganem, Joseph L DeRisi
Publikováno v:
PLoS Biology, Vol 1, Iss 2, p E2 (2003)
Because of the constant threat posed by emerging infectious diseases and the limitations of existing approaches used to identify new pathogens, there is a great demand for new technological methods for viral discovery. We describe herein a DNA microa
Externí odkaz:
https://doaj.org/article/a4b1da0943074850a9fb8b27b168c408
Autor:
Don Ganem
Publikováno v:
The Journal of Infectious Diseases. 218:S20-S24
Many careers are open to physician-scientists in the biotechnology and pharmaceutical sectors. However, research is structured very differently in these environments compared to academic medicine. This article highlights these differences and the rea
Autor:
Meghan Holdorf, Nadire Cochran, Lili Xie, Paul Feucht, Scott Clarkson, Kyoko Uehara, Gregory R. Hoffman, Darlene Chen, Don Ganem, Frederic Sigoillot, Carsten Russ, Anastasia Hyrina, Alicia Lindeman, Christopher T. Jones
GRAPHICAL ABSTRACTSUMMARYA hallmark of chronic hepatitis B virus (CHB) infection is the presence of high circulating levels of non-infectious small lipid HBV surface antigen (HBsAg) vesicles. Although rare, sustained HBsAg loss is the idealized endpo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260bc9cfe9475b4cb2496f1e7d32b1ec
Autor:
Frederic Sigoillot, Lili Xie, Don Ganem, Kyoko Uehara, Scott Clarkson, Carsten Russ, Nadire Cochran, Tiffany Tsang, Gregory R. Hoffman, Darlene Chen, Meghan Holdorf, Paul Feucht, Anastasia Hyrina, Christopher T. Jones, Alicia Lindeman
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 2970-2978.e6 (2019)
Summary: A hallmark of chronic hepatitis B (CHB) virus infection is the presence of high circulating levels of non-infectious small lipid HBV surface antigen (HBsAg) vesicles. Although rare, sustained HBsAg loss is the idealized endpoint of any CHB t
Autor:
JoLyn Turner, Jasmin Divers, Johanna Abend, James A. Snipes, Carl D. Langefeld, Pamela J. Hicks, Ashok K. Hemal, Amy L Kistler, Lijun Ma, Peter Skewes-Cox, Lihong Zhao, Barry I. Freedman, Don Ganem, Mitzie Spainhour, Douglas S. Lyles, Karl Skorecki, Mariana Murea
Publikováno v:
Nephrology Dialysis Transplantation.
BACKGROUND: Viral infections can trigger chronic kidney disease (CKD) and the urine virome may inform risk. The Natural History of APOL1-Associated Nephropathy Study (NHAANS) reported that urine JC polyomavirus (JCPyV) associated with a lower risk of