Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Don E. Griswold"'
Autor:
William M. Reiff, Charles DeBrosse, Joyce E Wawro, Elizabeth D Matz, Anvarhusein A. Isab, David T. Hill, C. Frank Shaw, James W. Webb, Michael J. DiMartino, Benjamin M. Jones, R. C. Elder, Don E. Griswold, Angel L Figueroa
Publikováno v:
Inorganic Chemistry. 49:7663-7675
Seleno-auranofin (SeAF), an analogue of auranofin (AF), the orally active antiarthritic gold drug in clinical use, was synthesized and has been characterized by an array of physical techniques and biological assays. The Mossbauer and extended X-ray a
Autor:
Michael Naso, Bailin Liang, Don E. Griswold, Danielle Lawrence, Lillian Shahied-Arruda, Michael R. D'Andrea, Xiao-Yu Song, Stanley M. Belkowski, Conway C. Huang, Ray Sweet, Bernard Amegadzie, Debbie A. Polkovitch
Publikováno v:
Journal of Investigative Dermatology. 127(7):1622-1631
Studies performed to discover genes overexpressed in inflammatory diseases identified dermokine as being upregulated in such disease conditions. Dermokine is a gene that was first observed as expressed in the differentiated layers of skin. Its two ma
Autor:
Farhat Syed, Li Li, X.-Y. R. Song, K. Li, V. Liu, Conway C. Huang, B. Y. Amegadzie, T. Shang, Don E. Griswold
Publikováno v:
Biomarkers. 12:414-423
Asthma is a chronic disorder characterized by airway inflammation, reversible bronchial obstruction, hyper-responsiveness and remodelling. Data from human in vitro studies and experimental in vivo models of asthma has implicated interleukin (IL)-13 i
Publikováno v:
Immunology. 119:296-305
Systemic lupus erythematosus (SLE) is an autoimmune disease resulting from dysregulation of the immune system. Interleukin-6 (IL-6) is a multifunctional cytokine produced by macrophages, monocytes and T and B cells. It stimulates B-cell differentiati
Autor:
J. Radewonuk, Jian Li, Don E. Griswold, Xiaozhou Shang, Eva Emmell, X.Y. Song, K.Y. Ma, Li Li
Publikováno v:
Cellular Immunology. 241:66-74
IgE plays a critical role in the pathogenesis of allergy and asthma. Therefore, suppression of IgE production would provide therapeutic benefits to patients suffering from these diseases. We have reported that the production of IgE is regulated diffe
Autor:
Jian Li, Li Li, Eva Emmell, Michelle Bracht, Don E. Griswold, Xiaozhou Shang, Jennifer Radewonuk
Publikováno v:
Cellular Immunology. 241:75-84
CD4+CD25+ regulatory T cells (Tr) are important in maintaining immune tolerance to self-antigen (Ag) and preventing autoimmunity. Reduced number and inadequate function of Tr are observed in chronic autoimmune diseases. Adoptively transferred Tr effe
Publikováno v:
International Immunopharmacology. 5:155-162
OKT3, a mouse anti-human CD3 monoclonal antibody (mAb), has been used for decades to reverse acute transplant rejection. A humanized OKT3 with two alanine replacements on the CH2 domain, hOKT3gamma1(Ala-Ala), was generated to reduce side effects of O
Autor:
David Peritt, Jackson Wan, Li Li, Li Sun, Jian Li, Theresa J Goletz, Don E. Griswold, M. Lamine Mbow, Gaoyun Yang, David Shealy, Allen Schantz
Publikováno v:
Cellular Immunology. 227:103-108
IL-18 is a pluripotent proinflammatory cytokine produced primarily by antigen presenting cells involved in numerous aspects of immune regulation most notably on lymphoid cells. The effect of IL-18 stimulation on cells in the myeloid compartment, howe
Autor:
Xiao-yu R. Song, Xinping Zhang, Regis J. O'Keefe, Susan V. Bukata, J. Edward Puzas, Don E. Griswold, Jill Gelinas, Edward M. Schwarz, Randy N. Rosier, Xiaochao Wei
Publikováno v:
Journal of Orthopaedic Research. 22:6-12
Aseptic loosening of orthopaedic implants is precipitated by wear debris-induced osteolysis. Central to this process are the pro-inflammatory mediators that are produced in response to wear by the fibroblastic cells, which comprise the majority of pe