Zobrazeno 1 - 10
of 3 283
pro vyhledávání: '"Don C. P."'
Autor:
Jerome C. Edelson, Scott F. D. Edelson, John G. Quiles, Cyrus V. Edelson, Eric M. Montminy, Christian L. Horn, John P. Magulick, Don C. Rockey
Publikováno v:
Portal Hypertension & Cirrhosis, Vol 3, Iss 2, Pp 67-74 (2024)
Abstract Aims Portal hypertension (PH) is a complication of cirrhosis that leads to hepatic decompensation. Assessing the portal pressure gradient (PPG) provides valuable information for disease assessment, staging, and prognosis. In this study, we a
Externí odkaz:
https://doaj.org/article/7011d32767c74ccf9442ab27280fb4c2
Autor:
Markus Götz, Anders Barth, Søren S. -R. Bohr, Richard Börner, Jixin Chen, Thorben Cordes, Dorothy A. Erie, Christian Gebhardt, Mélodie C. A. S. Hadzic, George L. Hamilton, Nikos S. Hatzakis, Thorsten Hugel, Lydia Kisley, Don C. Lamb, Carlos de Lannoy, Chelsea Mahn, Dushani Dunukara, Dick de Ridder, Hugo Sanabria, Julia Schimpf, Claus A. M. Seidel, Roland K. O. Sigel, Magnus B. Sletfjerding, Johannes Thomsen, Leonie Vollmar, Simon Wanninger, Keith R. Weninger, Pengning Xu, Sonja Schmid
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/1b1c0a8db83947af9fa8432a08f638ac
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract It is estimated that two-thirds of all proteins in higher organisms are composed of multiple domains, many of them containing discontinuous folds. However, to date, most in vitro protein folding studies have focused on small, single-domain p
Externí odkaz:
https://doaj.org/article/8f45765a0d4542fb98ea229e298fd32a
Protein folding is an indispensable process for the majority of proteins after their synthesis from ribosomes in the cell. Most in vitro protein folding studies have focused on single-domain proteins. Hence, it is important to understand the folding
Externí odkaz:
http://arxiv.org/abs/2112.08838
Autor:
Simon Wanninger, Pooyeh Asadiatouei, Johann Bohlen, Clemens-Bässem Salem, Philip Tinnefeld, Evelyn Ploetz, Don C. Lamb
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Single-molecule experiments have changed the way we explore the physical world, yet data analysis remains time-consuming and prone to human bias. Here, we introduce Deep-LASI (Deep-Learning Assisted Single-molecule Imaging analysis), a softw
Externí odkaz:
https://doaj.org/article/e1fe197473194049b53352200f89a7f4
Autor:
Hoyer, Maria, Crevenna, Alvaro H., Kitel, Radoslaw, Willems, Kherim, Czub, Miroslawa, Dubin, Grzegorz, Van Dorpe, Pol, Holak, Tad A., Lamb, Don C.
Protein assembly plays an important role throughout all phyla of life, both physiologically and pathologically. In particular, aggregation and polymerization of proteins are key-strategies that regulate cellular function. In recent years, methods to
Externí odkaz:
http://arxiv.org/abs/2106.13625
Autor:
Ivo M. Glück, Grusha Primal Mathias, Sebastian Strauss, Virgile Rat, Irene Gialdini, Thomas Sebastian Ebert, Che Stafford, Ganesh Agam, Suliana Manley, Veit Hornung, Ralf Jungmann, Christian Sieben, Don C. Lamb
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108382- (2023)
Summary: The NLRP3 inflammasome is a central component of the innate immune system. Its activation leads to formation of the ASC speck, a supramolecular assembly of the inflammasome adaptor protein ASC. Different models, based on ASC overexpression,
Externí odkaz:
https://doaj.org/article/f518dcc0b67d43c7ba16f7aa2b31c012
Publikováno v:
Harm Reduction Journal, Vol 20, Iss 1, Pp 1-10 (2023)
Abstract Background To examine COVID-19 vaccination and HIV transmission among persons who inject drugs (PWID) during the COVID-19 pandemic (2020–2022) in New York City (NYC). Methods Two hundred and seventy five PWID were recruited from October 20
Externí odkaz:
https://doaj.org/article/0b2d77a2515b46cbb0ed69fbe8a5b19f
Autor:
Lerner, Eitan, Ambrose, Benjamin, Barth, Anders, Birkedal, Victoria, Blanchard, Scott C., Borner, Richard, Cordes, Thorben, Craggs, Timothy D., Ha, Taekjip, Haran, Gilad, Hugel, Thorsten, Ingargiola, Antonino, Kapanidis, Achillefs, Lamb, Don C., Laurence, Ted, Lee, Nam ki, Lemke, Edward A., Margeat, Emmanuel, Michaelis, Jens, Michalet, Xavier, Nettels, Daniel, Peulen, Thomas-Otavio, Schuler, Benjamin, Seidel, Claus A. M., So-leimaninejad, Hamid, Weiss, Shimon
Publikováno v:
eLife 10 (2021) e60416
Single-molecule F\"{o}rster resonance energy transfer (smFRET) has become a mainstream technique for probing biomolecular structural dynamics. The rapid and wide adoption of the technique by an ever-increasing number of groups has generated many impr
Externí odkaz:
http://arxiv.org/abs/2006.03091
Autor:
Lionel Moulis, Sao Mai Le, Vinh Vu Hai, Duong Thi Huong, Khuê Pham Minh, Khuat Thi Hai Oanh, Delphine Rapoud, Catherine Quillet, Tuyết Thanh Nham Thi, Roselyne Vallo, Giang Thi Hoang, Jean-Pierre Moles, Didier Laureillard, Jonathan Feelemyer, Don C. Des Jarlais, Laurent Michel, Nicolas Nagot, the DRIVE Study Team
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundThe co-occurrence of substance use disorder and mental disorder, known as dual diagnosis, has a distressingly high prevalence among individuals grappling with either of these conditions. Mood disorders, especially depression, constitute a s
Externí odkaz:
https://doaj.org/article/601b0f533dca4e9bb81cb4e5abddf422