Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Don B. McClure"'
Autor:
Beverly L Falcon, Michelle Swearingen, Wendy H Gough, Linda Lee, Robert Foreman, Mark Uhlik, Jeff C Hanson, Jonathan A Lee, Don B McClure, Sudhakar Chintharlapalli
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106901 (2014)
Vascular endothelial growth factor (VEGF) plays a dominant role in angiogenesis. While inhibitors of the VEGF pathway are approved for the treatment of a number of tumor types, the effectiveness is limited and evasive resistance is common. One mechan
Externí odkaz:
https://doaj.org/article/da954fc5fdb943c6baa8aa37fcd78d65
Autor:
Ronit Rafaeloff-Phail, Laura J. Conner, Kimberlee J. Emerson, Don B. McClure, Wu-Kuang Yeh, Harold B. Brooks, Haihong Guo, Liyun Ding
Publikováno v:
Journal of Biological Chemistry. 279:52934-52939
AMP-activated protein kinase (AMPK) serves as an energy-sensing protein kinase that is activated by a variety of metabolic stresses that lower cellular energy levels. When activated, AMPK modulates a network of metabolic pathways that result in net i
Publikováno v:
Experimental Cell Research. 192:32-40
Mammalian cells contain a microsomal vitamin K-dependent carboxylase activity which catalyzes the gamma-carboxylation of glutamate. While most cells have a limited ability to fully gamma-carboxylate proteins, it has been suggested that the ability of
Autor:
Thomas P. Burris, Lorri L Burris, Keith R. Stayrook, Amanda K Nosie, Srilatha Raghuram, Fraydoon Rastinejad, Don B McClure, Sepideh Khorasanizadeh, Pengxiang Huang, Pamela M. Rogers
The nuclear receptors REV-ERBalpha (encoded by NR1D1) and REV-ERBbeta (NR1D2) have remained orphans owing to the lack of identified physiological ligands. Here we show that heme is a physiological ligand of both receptors. Heme associates with the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11dca48dc362f1538863929f42fb69fd
https://lirias.kuleuven.be/handle/123456789/592878
https://lirias.kuleuven.be/handle/123456789/592878
Publikováno v:
Nucleic Acids Research. 20:5485-5486
Publikováno v:
Journal of Supramolecular Structure. 14:47-63
A heat-sensitive, trypsin-sensitive factor that promoted growth and spreading of cells in serum-free, hormone-supplemented medium was partially purified from human serum. The major portion of the proteins in these preparations migrated upon SDS-polya
Publikováno v:
Journal of Cellular Physiology. 103:323-331
The growth requirements of SV40 transformed Balb/c-3T3 cells have been studied in the absence of serum. For growth in serum-free medium, the cells require (i) insulin, (ii) transferrin, and (iii) cis-unsaturated fatty acids added in combination with
Publikováno v:
Developmental Brain Research. 2:563-575
We cultured single cell suspensions derived from enzymatically digested rat and mouse brains in the serum-free, hormone-supplemented media originally established for culturing glioma (C6) and neuroblastoma cell lines (B104). We succeeded in selecting
Publikováno v:
Journal of Cellular Physiology. 129:207-214
Recently improved culture conditions for human adult arterial endothelial and smooth muscle cells from a wide variety of donors have been used to study the effects of lipoproteins on proliferation of both cell types in low serum culture medium. Optim
Autor:
Gordon Sato, Jennie Mather, Sugayuki Ohasa, Izumi Hayashi, Don B. McClure, Hideo Masui, Sharon E. Hutchings, Jane E. Bottenstein, Richard A. Wolfe, Angie Rizzino, Ginette Serrero, Reen Wu
Publisher Summary This chapter presents the practical details for the growth of cells in serum free hormone supplemented media. In the absence of serum, greater than usual care must be taken in preparation of the synthetic portion of the medium. Care
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b13bac83810c1a6b678c01a86f5da09c
https://doi.org/10.1016/s0076-6879(79)58127-0
https://doi.org/10.1016/s0076-6879(79)58127-0