Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Don B. Arnold"'
Autor:
Varuzhan Balasanyan, Kaori Watanabe, William P. Dempsey, Tommy L. Lewis, Jr., Le A. Trinh, Don B. Arnold
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2696-2705 (2017)
Summary: The essential organization of microtubules within neurons has been described; however, less is known about how neuronal actin is arranged and the functional implications of its arrangement. Here, we describe, in live cells, an actin-based st
Externí odkaz:
https://doaj.org/article/2704c6e136eb4ff0b112f82539eca436
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 658-665.e4 (2019)
Summary: CaMKIIα is a central mediator of bidirectional synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD). To study how CaMKIIα movement during plasticity is affected by soluble amyloid-β peptide oligomers
Externí odkaz:
https://doaj.org/article/9b95d3d605894d2dac4c4afc551adfa7
Autor:
Kaori Watanabe, Sarmad Al-Bassam, Yusuke Miyazaki, Thomas J. Wandless, Paul Webster, Don B. Arnold
Publikováno v:
Cell Reports, Vol 2, Iss 6, Pp 1546-1553 (2012)
Trafficking of proteins specifically to the axonal or somatodendritic membrane allows neurons to establish and maintain polarized compartments with distinct morphology and function. Diverse evidence suggests that an actin-dependent vesicle filter wit
Externí odkaz:
https://doaj.org/article/a56865220721411e9420bb5f403a8ef8
Publikováno v:
eLife, Vol 12 (2024)
The basolateral amygdala (BLA) is a key site where fear learning takes place through synaptic plasticity. Rodent research shows prominent low theta (~3–6 Hz), high theta (~6–12 Hz), and gamma (>30 Hz) rhythms in the BLA local field potential reco
Externí odkaz:
https://doaj.org/article/019dcb82422a4c1a9ef0155d27056de6
Differential Trafficking of Transport Vesicles Contributes to the Localization of Dendritic Proteins
Publikováno v:
Cell Reports, Vol 2, Iss 1, Pp 89-100 (2012)
In neurons, transmembrane proteins are targeted to dendrites in vesicles that traffic solely within the somatodendritic compartment. How these vesicles are retained within the somatodendritic domain is unknown. Here, we use a novel pulse-chase system
Externí odkaz:
https://doaj.org/article/7b7cdfb03dc040c09a1670f2749b1ee6
The basolateral amygdala (BLA) is a key site where fear learning takes place through synaptic plasticity. Rodent research shows prominent low theta (∼3-6 Hz), high theta (∼6-12 Hz), and gamma (>30 Hz) rhythms in the BLA local field potential reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61bf7d8ebf2e5a6f547f9c35c6634d4a
https://doi.org/10.1101/2023.04.28.538604
https://doi.org/10.1101/2023.04.28.538604
Autor:
William P. Dempsey, Zhuowei Du, Anna Nadtochiy, Colton D. Smith, Karl Czajkowski, Andrey Andreev, Drew N. Robson, Jennifer M. Li, Serina Applebaum, Thai V. Truong, Carl Kesselman, Scott E. Fraser, Don B. Arnold
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Imaging of labeled excitatory synapses in the intact brain before and after classical conditioning permits a longitudinal analysis of changes that accompany associative memory formation. When applied to midlarval stage zebrafish, this ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bc1c13c92a936207f7f87adef67285
https://doi.org/10.1073/pnas.2107661119
https://doi.org/10.1073/pnas.2107661119
Autor:
Varuzhan Balasanyan, Don B Arnold
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92349 (2014)
The localization of mRNAs within axons and dendrites allows neurons to manipulate protein levels in a time and location dependent manner and is essential for processes such as synaptic plasticity and axon guidance. However, an essential step in the p
Externí odkaz:
https://doaj.org/article/fda6c1dbc181463680bb28e6bb2832b6
Autor:
Christopher M, Davenport, Rajit, Rajappa, Ljudmila, Katchan, Charlotte R, Taylor, Ming-Chi, Tsai, Caleb M, Smith, Johannes W, de Jong, Don B, Arnold, Stephan, Lammel, Richard H, Kramer
Publikováno v:
Neuron. 109(1)
The excitatory synapse between hippocampal CA3 and CA1 pyramidal neurons exhibits long-term potentiation (LTP), a positive feedback process implicated in learning and memory in which postsynaptic depolarization strengthens synapses, promoting further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb9702074e5030aeac286b01be400736
https://pubmed.ncbi.nlm.nih.gov/33168997
https://pubmed.ncbi.nlm.nih.gov/33168997
Publikováno v:
PLoS Biology, Vol 9, Iss 3, p e1001021 (2011)
In neurons polarized trafficking of vesicle-bound membrane proteins gives rise to the distinct molecular composition and functional properties of axons and dendrites. Despite their central role in shaping neuronal form and function, surprisingly litt
Externí odkaz:
https://doaj.org/article/973eda0a0ad8434fa284642a323ea7ed