Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Domnita-Valeria Rusnac"'
Autor:
Guangfeng Zhou, Domnita-Valeria Rusnac, Hahnbeom Park, Daniele Canzani, Hai Minh Nguyen, Lance Stewart, Matthew F. Bush, Phuong Tran Nguyen, Heike Wulff, Vladimir Yarov-Yarovoy, Ning Zheng, Frank DiMaio
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Structure-based virtual screening is a key tool in early drug discovery, with growing interest in the screening of multi-billion chemical compound libraries. However, the success of virtual screening crucially depends on the accuracy of the
Externí odkaz:
https://doaj.org/article/29a1302972a44e30ab683de7520641e9
Autor:
Timothy M. Locke, Rose Fields, Hayden Gizinski, George M. Otto, Melissa J.S. MacEwen, Domnita-Valeria Rusnac, Peixian He, David M. Shechner, Chris D. McGann, Matthew D. Berg, Judit Villen, Yasemin Sancak, Devin K. Schweppe
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114879- (2024)
Summary: Calcium ions play important roles in nearly every biological process, yet whole-proteome analysis of calcium effectors has been hindered by a lack of high-throughput, unbiased, and quantitative methods to identify protein-calcium engagement.
Externí odkaz:
https://doaj.org/article/83058aefa024485bafa97ed7f25ab95d
Autor:
Melissa J.S. MacEwen, Domnita-Valeria Rusnac, Henok Ermias, Timothy M. Locke, Hayden E. Gizinski, Joseph P. Dexter, Yasemin Sancak
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106146- (2023)
Summary: Activation of myosin light chain kinase (MLCK) by calcium ions (Ca2+) and calmodulin (CaM) plays an important role in numerous cellular functions including vascular smooth muscle contraction and cellular motility. Despite extensive biochemic
Externí odkaz:
https://doaj.org/article/dfa9997666004496bd94070810bacbc7
Autor:
Melissa JS MacEwen, Domnita-Valeria Rusnac, Henok Ermias, Timothy M Locke, Hayden E Gizinski, Joseph P Dexter, Yasemin Sancak
Activation of myosin light-chain kinase (MLCK) by calcium ions (Ca2+) and calmodulin (CaM) plays an important role in numerous cellular functions including vascular smooth muscle contraction and cellular motility. Despite extensive biochemical analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e45606ed2d49b25f2900afb491867dcd
https://doi.org/10.1101/2022.06.08.495195
https://doi.org/10.1101/2022.06.08.495195
Autor:
Melissa MacEwen, Domnita-Valeria Rusnac, Henok Ermias, Timothy Locke, Hayden Gizinski, Joseph Dexter, Yasemin Sancak
Publikováno v:
Journal of Biological Chemistry. 299:104166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c902078df65898d3d5255a548e27cd9
https://doi.org/10.1016/j.jbc.2023.104166
https://doi.org/10.1016/j.jbc.2023.104166
Autor:
Gabriel J. H. Ahl, Jessica M. Stine, Domnita-Valeria Rusnac, Klára Briknarová, Casey Schlenker
Publikováno v:
Biochemistry. 56:4667-4675
Anastellin is a small recombinant fragment derived from the extracellular matrix protein fibronectin; it comprises the first type III (FN3) domain without the two N-terminal β-strands. It inhibits angiogenesis, tumor growth, and metastasis in mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac77cd09e2aaefb6ce2b42aeceab4b4
https://doi.org/10.1021/acs.biochem.7b00633
https://doi.org/10.1021/acs.biochem.7b00633
Autor:
Keshia M. Kerchner, Tung-Chung Mou, Yizhi Sun, Domniţa-Valeria Rusnac, Stephen R. Sprang, Klára Briknarová
Publikováno v:
Journal of Structural Biology: X, Vol 5, Iss , Pp 100050- (2021)
Euchromatic histone-lysine N-methyltransferase 1 (EHMT1; G9a-like protein; GLP) and euchromatic histone-lysine N-methyltransferase 2 (EHMT2; G9a) are protein lysine methyltransferases that regulate gene expression and are essential for development an
Externí odkaz:
https://doaj.org/article/31ace5596d2b4bfd8ba11c38db17413e