O09 Dynamic impact of chronic inflammation on epidermal autophagy pathway.

Autor: Uddin, Nazia, Ostano, Paola, Chiorino, Giovanna, Domizio, Jeremy di, Gilliet, Michel, Philpott, Mike, Hannen, Rosalind, Bergamaschi, Daniele

Publikováno v: British Journal of Dermatology; Jul2023, Vol. 189 Issue 1, pe7-e8, 2p

ID: 2: Paradoxical psoriasis – Unabated type I IFN production induced by TNF blockade.

Autor: Conrad, Curdin¹, Domizio, Jeremy Di¹, Mylonas, Alessio¹, Belkhodja, Cyrine¹, Demaria, Olivier¹, Navarini, Alexander², Lapointe, Anne-Karine², French, Lars², Vernez, Maxime², Gilliet, Michel¹

Publikováno v: Cytokine. Nov2015, Vol. 76 Issue 1, p66-66. 1p.

The cGAS–STING pathway drives type I IFN immunopathology in COVID-19

Autor: Jeremy Di Domizio, Muhammet F. Gulen, Fanny Saidoune, Vivek V. Thacker, Ahmad Yatim, Kunal Sharma, Théo Nass, Emmanuella Guenova, Martin Schaller, Curdin Conrad, Christine Goepfert, Laurence de Leval, Christophe von Garnier, Sabina Berezowska, Anaëlle Dubois, Michel Gilliet, Andrea Ablasser

Publikováno v: Nature, vol. 603, no. 7899, pp. 145-151
Nature
Domizio, Jeremy Di; Gulen, Muhammet F; Saidoune, Fanny; Thacker, Vivek V; Yatim, Ahmad; Sharma, Kunal; Nass, Théo; Guenova, Emmanuella; Schaller, Martin; Conrad, Curdin; Goepfert, Christine; de Leval, Laurence; Garnier, Christophe von; Berezowska, Sabina; Dubois, Anaëlle; Gilliet, Michel; Ablasser, Andrea (2022). The cGAS-STING pathway drives type I IFN immunopathology in COVID-19. Nature, 603(7899), pp. 145-151. Springer Nature 10.1038/s41586-022-04421-w

COVID-19, which is caused by infection with SARS-CoV-2, is characterized by lung pathology and extrapulmonary complications1,2. Type I interferons (IFNs) have an essential role in the pathogenesis of COVID-19 (refs 3–5). Although rapid induction of

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