Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Dominique Segretain"'
Autor:
Dominique Segretain, Mathilde Di Marco, Chloé Dufeu, Diane Carette, Alain Trubuil, Georges Pointis
Publikováno v:
Basic and Clinical Andrology, Vol 33, Iss 1, Pp 1-11 (2023)
Abstract Background The endocytosis of Gap junction plaques (GJP) requires cytoskeletal forces to internalize such large membranous structures. Actin, which partners the connexin proteins constituting Gap junctions and is located close to Annular Gap
Externí odkaz:
https://doaj.org/article/04defef642ed49a393a291ddd916ad35
Autor:
Dominique Segretain, Cendrine Geoffroy-Siraudin, Nadia Prisant, Marie-HĂŠlene Perrard, Georges Pointis, Marie-Roberte Guichaoua, Philippe Durand
Publikováno v:
Folia Histochemica et Cytobiologica, Vol 47, Iss 5, Pp 89-94 (2010)
Spermatogenesis involves the realization of a particular genetic program which requires a specific environment ("niche"). Multiplication, differentiation and apoptosis of male germ cells are finely regulated by pituitary hormones (mainly LH and FSH),
Externí odkaz:
https://doaj.org/article/9b26c95d990444278be0e368006c7227
Autor:
Mark Kibschull, Dominique Segretain, Alexandra Gellhaus, Diane Carette, Georges Pointis, Jerome Gilleron
Publikováno v:
Cellular and Molecular Life Sciences. 72:2879-2898
Reproductive organs are complex and well-structured tissues essential to perpetuate the species. In mammals, the male and female reproductive organs vary on their organization, morphology and function. Connectivity between cells in such tissues plays
Autor:
Jean-Pierre Denizot, Georges Pointis, Dominique Segretain, Kirsty Grant, Jerome Gilleron, Diane Carette
Publikováno v:
Biology of the Cell. 107:218-231
Connexins (Cx), the constitutive proteins of gap junctions, are key actors of many physiological processes. Therefore alterations of Cx expression and degradation lead to the development of physiopathological disorders. Due to the formation of a doub
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1860(1)
Cell death is a fundamental process for organogenesis, immunity and cell renewal. During the last decades a broad range of molecular tools were identified as important players for several different cell death pathways (apoptosis, pyroptosis, necrosis
Autor:
V. Mauro, R. Pontier-Bres, Georges Pointis, Jerome Gilleron, Diane Carette, D. Czerucka, J. Dompierre, Dominique Segretain
Publikováno v:
Apoptosis. 18:480-491
Griseofulvin, a widely used antifungal antimitotic drug has been proposed as an anti-tumoral treatment by way of in vitro experiments. Recently, in vivo demonstration of griseofulvin efficacy against multiple myeloma in mice argues for its potential
Autor:
Dominique Segretain, Georges Pointis, Diane Carette, M. Di Marco, Jean-Noël Bacro, Jerome Gilleron
Publikováno v:
Basic and clinical andrology
Basic and clinical andrology, BioMed Central, 2016, 26 (5), ⟨10.1186/s12610-016-0032-9⟩
Basic and Clinical Andrology
Basic and clinical andrology, BioMed Central, 2016, 26 (5), ⟨10.1186/s12610-016-0032-9⟩
Basic and Clinical Andrology
Background NRD convertase, also termed Nardilysin, is a Zn++ metalloendopeptidase that specifically cleaves the N-terminus of arginine and lysine residues into dibasic moieties. Although this enzyme was found located within the testis, its function i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a15dff126b279a9c0fdfd8c75b1a57
https://hal.archives-ouvertes.fr/hal-01297923
https://hal.archives-ouvertes.fr/hal-01297923
Publikováno v:
Spermatogenesis. 1:303-317
Many recent epidemiological, clinical and experimental findings support the hypothesis that environmental toxicants are responsible for the increasing male reproductive disorders (congenital malformations, declining sperm counts and testicular cancer
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 365:1607-1620
Spermatogenesis is a highly regulated process of germ cell proliferation and differentiation, starting from spermatogonia to spermatocytes and giving rise to spermatids, the future spermatozoa. In addition to endocrine regulation, testicular cell–c
Publikováno v:
Biochimie. 92:555-559
The role of gap junctions in proliferation, differentiation and apoptosis has been recently highlighted. Nevertheless, the molecular mechanisms that control these physiological events by acting on gap junction channels are still unknown. We have rece