Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Dominique Muschter"'
Autor:
Gundula Rösch, Dominique Muschter, Shahed Taheri, Karima El Bagdadi, Christoph Dorn, Andrea Meurer, Frank Zaucke, Arndt F. Schilling, Susanne Grässel, Rainer H. Straub, Zsuzsa Jenei-Lanzl
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
PurposeRecent studies demonstrated a contribution of adrenoceptors (ARs) to osteoarthritis (OA) pathogenesis. Several AR subtypes are expressed in joint tissues and the β2-AR subtype seems to play a major role during OA progression. However, the imp
Externí odkaz:
https://doaj.org/article/5c0a86ee5417455389e968e0473b4ae6
Autor:
Gundula Rösch, Dominique Muschter, Karima El Bagdadi, Shahed Taheri, Andrea Meurer, Arndt F. Schilling, Susanne Grässel, Rainer H. Straub, Frank Zaucke, Zsuzsa Jenei-Lanzl
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101042- (2021)
Externí odkaz:
https://doaj.org/article/8ef8fd4be5d9420cb19e465890650c77
Autor:
Lutz Fleischhauer, Dominique Muschter, Zsuzsanna Farkas, Susanne Grässel, Attila Aszodi, Hauke Clausen-Schaumann, Paolo Alberton
Publikováno v:
Applied Sciences, Vol 12, Iss 5, p 2596 (2022)
Destabilization of the medial meniscus (DMM) surgery in mice is used to elucidate the mechanism of post-traumatic osteoarthritis (PT-OA). The study of cartilage biomechanics in PT-OA is important for understanding the pathophysiology of the condition
Externí odkaz:
https://doaj.org/article/7537d7a98cc543beb29cfd6ce835fb3c
Autor:
Susanne Grässel, Dominique Muschter
Publikováno v:
F1000Research, Vol 9 (2020)
Osteoarthritis (OA) is one of the most debilitating diseases and is associated with a high personal and socioeconomic burden. So far, there is no therapy available that effectively arrests structural deterioration of cartilage and bone or is able to
Externí odkaz:
https://doaj.org/article/839e7174e0da47e98e8f7970f9f3374b
Autor:
Ute Nazet, Agnes Schröder, Susanne Grässel, Dominique Muschter, Peter Proff, Christian Kirschneck
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225790 (2019)
Selection of appropriate housekeeping genes is essential for the validity of data normalization in reverse transcription quantitative PCR (RT-qPCR). Synovial fibroblasts (SF) play a mediating role in the development and progression of osteoarthritis
Externí odkaz:
https://doaj.org/article/6a19342d7a924a58ac693bcd7de2a20a
Autor:
Ute Nazet, Laura Feulner, Dominique Muschter, Patrick Neubert, Valentin Schatz, Susanne Grässel, Jonathan Jantsch, Peter Proff, Agnes Schröder, Christian Kirschneck
Publikováno v:
Cells, Vol 10, Iss 2, p 298 (2021)
Genetic predisposition, traumatic events, or excessive mechanical exposure provoke arthritic changes in the temporomandibular joint (TMJ). We analysed the impact of mechanical stress that might be involved in the development and progression of TMJ os
Externí odkaz:
https://doaj.org/article/3a8f0c1d913945e5b4f1de410471184f
Autor:
Frank Haubner, Dominique Muschter, Fabian Pohl, Stephan Schreml, Lukas Prantl, Holger G. Gassner
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 25947-25958 (2015)
External radiation seems to be associated with increased amounts of cytokines and other cellular modulators. Impaired microcirculation and fibrosis are examples of typical long term damage caused by radiotherapy. Adipose tissue-derived stem cells (AS
Externí odkaz:
https://doaj.org/article/8a3f0ae5051143eab561383db42199db
Autor:
Dominique Muschter, Anna-Sophie Beiderbeck, Tanja Späth, Christian Kirschneck, Agnes Schröder, Susanne Grässel
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 503 (2019)
This study aimed to analyze if the sensory neuropeptide SP (SP) and the neurokinin receptor 1 (NK1R) are involved in macrophage mechano-transduction, similar to chondrocytes, and if alpha-calcitonin gene-related peptide (αCGRP) and the CGRP receptor
Externí odkaz:
https://doaj.org/article/349bd563e3cf4e148013e33e2dbcc7c2
Autor:
Agnes Schröder, Ute Nazet, Dominique Muschter, Susanne Grässel, Peter Proff, Christian Kirschneck
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 3, p 585 (2019)
Osteoarthritis (OA) affects the integrity of the entire joint including the synovium. The most abundant cells in the synovium are fibroblasts (SF). Excessive mechanical loading might contribute to OA pathogenesis. Here, we investigate the effects of
Externí odkaz:
https://doaj.org/article/4029579b483b456a8766b934a821a31b
Autor:
Susanne Grässel, Dominique Muschter
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 2, p 367 (2018)
Joint tissues like synovium, articular cartilage, meniscus and subchondral bone, are targets for neuropeptides. Resident cells of these tissues express receptors for various neuroendocrine-derived peptides including proopiomelanocortin (POMC)-derived
Externí odkaz:
https://doaj.org/article/8fe33754213b414690d7851853eda260