Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Dominique Mengin-Lecreulx"'
Autor:
Jula Reuter, Christian Otten, Nicolas Jacquier, Junghoon Lee, Dominique Mengin-Lecreulx, Iris Löckener, Robert Kluj, Christoph Mayer, Federico Corona, Julia Dannenberg, Sébastien Aeby, Henrike Bühl, Gilbert Greub, Waldemar Vollmer, Scot P Ouellette, Tanja Schneider, Beate Henrichfreise
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011047 (2023)
The obligate intracellular Chlamydiaceae do not need to resist osmotic challenges and thus lost their cell wall in the course of evolution. Nevertheless, these pathogens maintain a rudimentary peptidoglycan machinery for cell division. They build a t
Externí odkaz:
https://doaj.org/article/fdf8f7a7bce540f6b36caa5585ecad53
Autor:
Farshid Jalalvand, Yu-Ching Su, Guillaume Manat, Alexey Chernobrovkin, Mahendar Kadari, Sandra Jonsson, Martina Janousková, Dorothea Rutishauser, Szabolcs Semsey, Anders Løbner-Olesen, Linda Sandblad, Klas Flärdh, Dominique Mengin-Lecreulx, Roman A. Zubarev, Kristian Riesbeck
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
The human pathogen Haemophilus influenzae causes respiratory tract infections and is commonly associated with prolonged carriage in patients with chronic obstructive pulmonary disease. Production of outer membrane vesicles (OMVs) is a ubiquitous phen
Externí odkaz:
https://doaj.org/article/70ab3a33c8d84209897232a1f10d2f9e
Autor:
Xudong Tian, Guillaume Manat, Elise Gasiorowski, Rodolphe Auger, Samia Hicham, Dominique Mengin-Lecreulx, Ivo Gomperts Boneca, Thierry Touzé
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The cell surface of Gram-negative bacteria usually exhibits a net negative charge mostly conferred by lipopolysaccharides (LPS). This property sensitizes bacterial cells to cationic antimicrobial peptides, such as polymyxin B, by favoring their bindi
Externí odkaz:
https://doaj.org/article/4fe97d1e463f46199baca02806b86190
Autor:
Ming-Yuan Su, Nilanjan Som, Chia-Yun Wu, Shih-Chieh Su, Yi-Ting Kuo, Lu-Chu Ke, Meng-Ru Ho, Shiou-Ru Tzeng, Ching-Hao Teng, Dominique Mengin-Lecreulx, Manjula Reddy, Chung-I Chang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
MepS is a peptidoglycan (PG) cross-link specific hydrolase needed for cell wall expansion and its cellular levels must be tightly regulated. Here the authors present the structure of the MepS degrading protease Prc bound to its adaptor NlpI and propo
Externí odkaz:
https://doaj.org/article/2eee51eaba5b45a6a5a94b3bbceba1cd
Autor:
Miao Ma, Margaux Lustig, Michèle Salem, Dominique Mengin-Lecreulx, Gilles Phan, Isabelle Broutin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 10, p 5328 (2021)
One of the major families of membrane proteins found in prokaryote genome corresponds to the transporters. Among them, the resistance-nodulation-cell division (RND) transporters are highly studied, as being responsible for one of the most problematic
Externí odkaz:
https://doaj.org/article/d1c8d355634f448ea3ebd9d65c15d3ad
Autor:
Elise Gasiorowski, Rodolphe Auger, Xudong Tian, Samia Hicham, Chantal Ecobichon, Sophie Roure, Martin V Douglass, M Stephen Trent, Dominique Mengin-Lecreulx, Thierry Touzé, Ivo Gomperts Boneca
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1007972 (2019)
The biogenesis of bacterial cell-envelope polysaccharides requires the translocation, across the plasma membrane, of sugar sub-units that are produced inside the cytoplasm. To this end, the hydrophilic sugars are anchored to a lipid phosphate carrier
Externí odkaz:
https://doaj.org/article/4defe23ba9ba4e338d69a1e4e4d9d43a
Autor:
Tommaso Tosi, Fumiya Hoshiga, Charlotte Millership, Rahul Singh, Charles Eldrid, Delphine Patin, Dominique Mengin-Lecreulx, Konstantinos Thalassinos, Paul Freemont, Angelika Gründling
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007537 (2019)
c-di-AMP is an important second messenger molecule that plays a pivotal role in regulating fundamental cellular processes, including osmotic and cell wall homeostasis in many Gram-positive organisms. In the opportunistic human pathogen Staphylococcus
Externí odkaz:
https://doaj.org/article/d723f21044c24d7f807389cc25aa03cd
Autor:
Jean-Emmanuel Hugonnet, Dominique Mengin-Lecreulx, Alejandro Monton, Tanneke den Blaauwen, Etienne Carbonnelle, Carole Veckerlé, Yves, V. Brun, Michael van Nieuwenhze, Christiane Bouchier, Kuyek Tu, Louis B Rice, Michel Arthur
Publikováno v:
eLife, Vol 5 (2016)
The target of β-lactam antibiotics is the D,D-transpeptidase activity of penicillin-binding proteins (PBPs) for synthesis of 4→3 cross-links in the peptidoglycan of bacterial cell walls. Unusual 3→3 cross-links formed by L,D-transpeptidases were
Externí odkaz:
https://doaj.org/article/c13d2d0e04b94f25b8075923cab7548f
Autor:
Qingping Xu, Dominique Mengin-Lecreulx, Xueqian W. Liu, Delphine Patin, Carol L. Farr, Joanna C. Grant, Hsiu-Ju Chiu, Lukasz Jaroszewski, Mark W. Knuth, Adam Godzik, Scott A. Lesley, Marc-André Elsliger, Ashley M. Deacon, Ian A. Wilson
Publikováno v:
mBio, Vol 6, Iss 5 (2015)
ABSTRACT Bacterial SH3 (SH3b) domains are commonly fused with papain-like Nlp/P60 cell wall hydrolase domains. To understand how the modular architecture of SH3b and NlpC/P60 affects the activity of the catalytic domain, three putative NlpC/P60 cell
Externí odkaz:
https://doaj.org/article/66e5fd174c9b48308e36f26975b3b4c4
Autor:
Guillaume Manat, Meriem El Ghachi, Rodolphe Auger, Karima Baouche, Samir Olatunji, Frédéric Kerff, Thierry Touzé, Dominique Mengin-Lecreulx, Ahmed Bouhss
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142870 (2015)
Several integral membrane proteins exhibiting undecaprenyl-pyrophosphate (C55-PP) phosphatase activity were previously identified in Escherichia coli that belonged to two distinct protein families: the BacA protein, which accounts for 75% of the C55-
Externí odkaz:
https://doaj.org/article/1701164c9a5a47f2961811ce12dcb10e