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pro vyhledávání: '"Dominique M. S. Buyens"'
Publikováno v:
Molecules, Vol 27, Iss 18, p 6111 (2022)
The adeninate anion (Ade−) is a useful nucleophile used in the synthesis of many prodrugs (including those for HIV AIDS treatment). It exists as a contact ion-pair (CIP) with Na+ and K+ (M+) but the site of coordination is not obvious from spectros
Externí odkaz:
https://doaj.org/article/c2f3a2e8888a40ed95d16a479c736455
Publikováno v:
Chemphyschem
Rare anionic forms of nucleic acids play a significant biological role and lead to spontaneous mutations and replication and translational errors. There is a lack of information surrounding the stability and reactivity of these forms. Ion pairs of mo
Publikováno v:
Journal of Heterocyclic Chemistry. 54:2946-2950
The preferred sites for the benzylation of adenine under basic conditions were proven to be the N9 and N3 positions. Formation of the N9-benzyladenine product is favored in polar aprotic solvents, such as DMSO, whereas the proportion of N3-benzyladen