Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Dominique Linard"'
Autor:
Sarah Barelier, Dominique Linard, Julien Pons, André Clippe, Bernard Knoops, Jean-Marc Lancelin, Isabelle Krimm
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9744 (2010)
The search for protein ligands is a crucial step in the inhibitor design process. Fragment screening represents an interesting method to rapidly find lead molecules, as it enables the exploration of a larger portion of the chemical space with a small
Externí odkaz:
https://doaj.org/article/499a58ea816d4ef1a2622b029f23831b
Autor:
Bernard Knoops, Andrea Kandlbinder, Karl-Josef Dietz, Pierre Morsomme, Hervé Degand, Dominique Linard
Publikováno v:
Archives of Biochemistry and Biophysics. 491:39-45
Mitochondria are metabolically highly active cell organelles that are also implicated in reactive oxygen species production and in cell death regulation. Cyclophilin D, the only human mitochondrial isoform of cyclophilins, plays an essential role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23ca6973b46c30225c35dfde03af4eb
https://doi.org/10.1016/j.abb.2009.09.002
https://doi.org/10.1016/j.abb.2009.09.002
Publikováno v:
Archives of Biochemistry and Biophysics. 477:98-104
Peroxiredoxin 5 (PRDX5) belongs to the PRDX superfamily of thiol-dependent peroxidases able to reduce hydrogen peroxide, alkyl hydroperoxides and peroxynitrite. PRDX5 is classified in the atypical 2-Cys subfamily of PRDXs. In this subfamily, the oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31577ed7aec24dfe06476c34c6a5576
https://doi.org/10.1016/j.abb.2008.04.036
https://doi.org/10.1016/j.abb.2008.04.036
Publikováno v:
Journal of neurochemistry. 125(3)
Peroxiredoxin-5 (PRDX5) is an antioxidant enzyme which differs from the other peroxiredoxins with regards to its enzymatic mechanism, its high affinity for organic peroxides and peroxynitrite and its wide subcellular distribution. In particular, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f42ffc5319c8c89c4eef19bd438fbeb
https://pubmed.ncbi.nlm.nih.gov/23216451
https://pubmed.ncbi.nlm.nih.gov/23216451
Autor:
Isabelle Krimm, Sarah Barelier, Dominique Linard, Bernard Knoops, André Clippe, Jean-Marc Lancelin, Julien Pons
Publikováno v:
PLoS ONE
PLoS ONE, 2010, 5 (3), pp.e9744. ⟨10.1371/journal.pone.0009744⟩
PLoS ONE, Vol 5, Iss 3, p e9744 (2010)
PLoS ONE, 2010, 5 (3), pp.e9744. ⟨10.1371/journal.pone.0009744⟩
PLoS ONE, Vol 5, Iss 3, p e9744 (2010)
The search for protein ligands is a crucial step in the inhibitor design process. Fragment screening represents an interesting method to rapidly find lead molecules, as it enables the exploration of a larger portion of the chemical space with a small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa2825b7b3ada1e8f5960cbb4d7ca48
https://hal.science/hal-03766713
https://hal.science/hal-03766713
