A fast, flexible simulation framework for Bayesian adaptive designs -- the R package BATSS

Autor: Couturier, Dominique-Laurent, Ryan, Elizabeth G, Puhr, Rainer, Jaki, Thomas, Heritier, Stephane

The use of Bayesian adaptive designs for randomised controlled trials has been hindered by the lack of software readily available to statisticians. We have developed a new software package (Bayesian Adaptive Trials Simulator Software - BATSS for the

Externí odkaz: http://arxiv.org/abs/2410.02050

Can warning labels communicating the environmental impact of meat reduce meat consumption? Evidence from two multiple treatment reversal experiments in college dining halls

Autor: Vasiljevic, Milica, Hughes, Jack P., Andersen, Christina D., Pennington, Georgia, Leite, Ana C., Weick, Mario, Couturier, Dominique-Laurent

Publikováno v: In Food Quality and Preference June 2024 115

Medicines and Healthcare products Regulatory Agency’s 'Consultation on proposals for legislative changes for clinical trials': a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing

Autor: Martin Law, Dominique-Laurent Couturier, Babak Choodari-Oskooei, Phillip Crout, Carrol Gamble, Peter Jacko, Philip Pallmann, Mark Pilling, David S. Robertson, Michael Robling, Matthew R. Sydes, Sofía S. Villar, James Wason, Graham Wheeler, S. Faye Williamson, Christina Yap, Thomas Jaki

Publikováno v: Trials, Vol 24, Iss 1, Pp 1-5 (2023)

Abstract In the UK, the Medicines and Healthcare products Regulatory Agency consulted on proposals “to improve and strengthen the UK clinical trials legislation to help us make the UK the best place to research and develop safe and innovative medic

Externí odkaz: https://doaj.org/article/b3bab057419146f7a2a0ab4aaefdc771

Medicines and Healthcare products Regulatory Agency's "Consultation on proposals for legislative changes for clinical trials": a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing.

Autor: Law, Martin^1,2 (AUTHOR) martin.law@mrc-bsu.cam.ac.uk, Couturier, Dominique-Laurent^1,3 (AUTHOR), Choodari-Oskooei, Babak⁴ (AUTHOR), Crout, Phillip¹ (AUTHOR), Gamble, Carrol⁵ (AUTHOR), Jacko, Peter^6,7 (AUTHOR), Pallmann, Philip⁸ (AUTHOR), Pilling, Mark⁹ (AUTHOR), Robertson, David S.¹ (AUTHOR), Robling, Michael⁸ (AUTHOR), Sydes, Matthew R.^4,10 (AUTHOR), Villar, Sofía S.¹ (AUTHOR), Wason, James¹¹ (AUTHOR), Wheeler, Graham¹² (AUTHOR), Williamson, S. Faye¹¹ (AUTHOR), Yap, Christina¹³ (AUTHOR), Jaki, Thomas^1,14 (AUTHOR)

Publikováno v: Trials. 10/5/2023, Vol. 24 Issue 1, p1-5. 5p.

Comparison of tumor‐informed and tumor‐naïve sequencing assays for ctDNA detection in breast cancer

Autor: Angela Santonja, Wendy N Cooper, Matthew D Eldridge, Paul A W Edwards, James A Morris, Abigail R Edwards, Hui Zhao, Katrin Heider, Dominique‐Laurent Couturier, Aadhitthya Vijayaraghavan, Paulius Mennea, Emma‐Jane Ditter, Christopher G Smith, Chris Boursnell, Raquel Manzano García, Oscar M Rueda, Emma Beddowes, Heather Biggs, Stephen‐John Sammut, Nitzan Rosenfeld, Carlos Caldas, Jean E Abraham, Davina Gale

Publikováno v: EMBO Molecular Medicine, Vol 15, Iss 6, Pp 1-20 (2023)

Abstract Analysis of circulating tumor DNA (ctDNA) to monitor cancer dynamics and detect minimal residual disease has been an area of increasing interest. Multiple methods have been proposed but few studies have compared the performance of different

Externí odkaz: https://doaj.org/article/2ec3b01381ac40e08e679d1a4763d28e