Zobrazeno 1 - 10 of 135 pro vyhledávání: '"Dominique Lagadic- Gossmann"'
1
Akademický článek
Exploration of microRNAs from blood extracellular vesicles as biomarkers of exposure to polycyclic aromatic hydrocarbons
Autor: Jérémy Amossé, Rima Souki, Maguy El Hajjar, Marie Marques, Valentine Genêt, Alexis Février, Morgane Le Gall, Benjamin SaintPierre, Franck Letourneur, Eric Le Ferrec, Dominique Lagadic-Gossmann, Christine Demeilliers, Lydie Sparfel
Publikováno v: Ecotoxicology and Environmental Safety, Vol 285, Iss , Pp 117065- (2024)
Exposure to polycyclic aromatic hydrocarbons (PAHs), ubiquitously environmental contaminant, leads to the development of major toxic effects on human health, such as carcinogenic and immunosuppressive alterations reported for the most studied PAH, i.
Externí odkaz: https://doaj.org/article/1b407791d61841db8c2e4541123ec996
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2
Akademický článek
Lipophilic components of diesel exhaust particles induce pro-inflammatory responses in human endothelial cells through AhR dependent pathway(s)
Autor: Bendik C. Brinchmann, Tonje Skuland, Mia H. Rambøl, Krisztina Szoke, Jan E. Brinchmann, Arno C. Gutleb, Elisa Moschini, Alena Kubátová, Klara Kukowski, Eric Le Ferrec, Dominique Lagadic-Gossmann, Per E. Schwarze, Marit Låg, Magne Refsnes, Johan Øvrevik, Jørn A. Holme
Publikováno v: Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-17 (2018)
Abstract Background Exposure to traffic-derived particulate matter (PM), such as diesel exhaust particles (DEP), is a leading environmental cause of cardiovascular disease (CVD), and may contribute to endothelial dysfunction and development of athero
Externí odkaz: https://doaj.org/article/485c00c5f20b41508f91ea534936799b
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3
Akademický článek
Benzo(a)pyrene triggers desensitization of β2-adrenergic pathway
Autor: Abdullah Mayati, Normand Podechard, Manuelle Rineau, Lydie Sparfel, Dominique Lagadic-Gossmann, Olivier Fardel, Eric Le Ferrec
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Exposure to environmental polycyclic aromatic hydrocarbons (PAHs), such as benzo(a)pyrene (B(a)P), has been linked to several health-threatening risks. PAHs were also shown to hinder adrenergic receptor (ADR) responses. As we previously demo
Externí odkaz: https://doaj.org/article/c8613d3a23d14ba8b04f0210cc5654ff
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4
Akademický článek
Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype
Autor: Kévin Hardonnière, Morgane Fernier, Isabelle Gallais, Baharia Mograbi, Normand Podechard, Eric Le Ferrec, Nathalie Grova, Brice Appenzeller, Agnès Burel, Martine Chevanne, Odile Sergent, Laurence Huc, Sylvie Bortoli, Dominique Lagadic-Gossmann
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Most tumors undergo metabolic reprogramming towards glycolysis, the so-called Warburg effect, to support growth and survival. Overexpression of IF1, the physiological inhibitor of the F0F1ATPase, has been related to this phenomenon and appea
Externí odkaz: https://doaj.org/article/1ca6f3d18d574609b106ab4e3f97c2b7
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9
A New In Vivo Zebrafish Bioassay Evaluating Liver Steatosis Identifies DDE as a Steatogenic Endocrine Disruptor, Partly through SCD1 Regulation
Autor: Hélène Le Mentec, Emmanuelle Monniez, Antoine Legrand, Céline Monvoisin, Dominique Lagadic-Gossmann, Normand Podechard
Publikováno v: International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3942
International Journal of Molecular Sciences, 2023, 24 (4), ⟨10.3390/ijms24043942⟩
International audience; Non-alcoholic fatty liver disease (NAFLD), which starts with liver steatosis, is a growing worldwide epidemic responsible for chronic liver diseases. Among its risk factors, exposure to environmental contaminants, such as endo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df81f05526cd503753c1a8134637676
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10
Small RNA-sequencing reveals the involvement of microRNA-132 in benzo[a]pyrene-induced toxicity in primary human blood cells
Autor: Rima Souki, Jérémy Amosse, Valentine Genêt, Morgane Le Gall, Benjamin Saintpierre, Franck Letourneur, Anne Maître, Christine Demeilliers, Eric Le Ferrec, Dominique Lagadic-Gossmann, Normand Podechard, Lydie Sparfel
Publikováno v: Environmental Pollution
Environmental Pollution, 2023, 328, pp.121653. ⟨10.1016/j.envpol.2023.121653⟩
International audience; Polycyclic aromatic hydrocarbons (PAHs) are widely distributed environmental contaminants, triggering deleterious effects such as carcinogenicity and immunosuppression, and peripheral blood mononuclear cells (PBMCs) are among
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5781aee4c4048d822ae7c256c4cf737c
https://doi.org/10.1016/j.envpol.2023.121653
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