Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dominique L. Kunciw"'
Autor:
Dominique L. Kunciw, David Hymel, Robert A. Grant, Ramesh M. Chingle, Kohei Tsuji, Terrence R. Burke, Michael B. Yaffe
Publikováno v:
Organic & Biomolecular Chemistry
Targeting protein – protein interactions (PPIs) has emerged as an important area of discovery for anticancer therapeutic development. In the case of phospho-dependent PPIs, such as the polo-like kinase 1 (Plk1) polo-box domain (PBD), a phosphorylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59bdb84f3cacad348c4725478049594
https://pubmed.ncbi.nlm.nih.gov/34346472
https://pubmed.ncbi.nlm.nih.gov/34346472
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(17)
Quaternized triflupromazine derivatives (QTDs) must possess benzyl groups attached to the quaternary nitrogen in order to have significant antitubercular potency. Replacing the quaternary amine with a triazole abolishes antitubercular activity. A mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4e80df6c621f5498e9856129e0d9fe
https://pubmed.ncbi.nlm.nih.gov/22850215
https://pubmed.ncbi.nlm.nih.gov/22850215
Autor:
Nie, Feilin1, Kunciw, Dominique L.1, Wilcke, David1, Stokes, Jamie E.1, Galloway, Warren R. J. D.1, Bartlett, Sean1, Sore, Hannah F.1, Spring, David R.1 spring@ch.cam.ac.uk
Publikováno v:
Angewandte Chemie. 9/5/2016, Vol. 128 Issue 37, p11305-11309. 5p.
Publikováno v:
Organic & Biomolecular Chemistry; 9/28/2021, Vol. 19 Issue 36, p7729-7735, 7p
Autor:
Hymel, David, Tsuji, Kohei, Grant, Robert A., Chingle, Ramesh M., Kunciw, Dominique L., Yaffe, Michael B., Burke, Terrence R.
Publikováno v:
Organic & Biomolecular Chemistry; 9/28/2021, Vol. 19 Issue 36, p7843-7854, 12p
Autor:
Sharma, Pooja1, Mahen, Robert1, Rossmann, Maxim2, Stokes, Jamie E.3, Hardwick, Bryn1, Huggins, David J.4, Emery, Amy1, Kunciw, Dominique L.3, Hyvönen, Marko2, Spring, David R.3, McKenzie, Grahame J.1, Venkitaraman, Ashok R.1 arv22@mrc-cu.cam.ac.uk
Publikováno v:
Scientific Reports. 11/4/2019, Vol. 9 Issue 1, pN.PAG-N.PAG. 1p.