Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Dominique Gatto"'
Autor:
Chris Weatherall, Jian Cheng Qi, Dominique Gatto, Ewan K.A. Millar, Peyman Mirarabshahi, Bill Giannakopoulos, M. Qi, Kumiko Tanaka, Derek Spielman, Steven A. Krilis, Leon Vonthethoff
Publikováno v:
Arthritis & Rheumatology. 66:2270-2280
Objective The BXSB.Yaa mouse strain is a model of systemic lupus erythematosus that is dependent on duplication of the Toll-like receptor 7 gene. The objective of this study was to systematically describe the amplified autoimmune phenotype observed w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::635c393e21fbdab6d7862aa2b78ea306
https://doi.org/10.1002/art.38646
https://doi.org/10.1002/art.38646
Marginal zone (MZ) B cells are thought to be responsible for the first wave of Abs against bacterial Ags. In this study, we assessed the in vivo response of MZ B cells in mice immunized with viral particles derived from the RNA phage Qβ. We found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df4f7bec070fbfbbe7c61603514cf92
https://ora.ox.ac.uk/objects/uuid:31511ac3-be04-4a29-8d61-c7275d64e4b2
https://ora.ox.ac.uk/objects/uuid:31511ac3-be04-4a29-8d61-c7275d64e4b2
Autor:
Sidonia Fagarasan, Robert J. Rigby, Roybel R. Ramiscal, Jennifer L. Marshall, Tyani D. Chan, Dimitra Zotos, Adam F. Cunningham, Louis M. Tsai, Sau K. Lee, David M. Tarlinton, Carola G. Vinuesa, Di Yu, Shimpei Kawamoto, Robert Brink, Dominique Gatto
Publikováno v:
The Journal of Experimental Medicine
Bcl-6 expression in CD4+ T cells is required to generate extrafollicular antibody responses.
T follicular helper cells (Tfh cells) localize to follicles where they provide growth and selection signals to mutated germinal center (GC) B cells, thu
T follicular helper cells (Tfh cells) localize to follicles where they provide growth and selection signals to mutated germinal center (GC) B cells, thu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8876a176cd3adeefc2eaf7cb9cddd9d3
https://doi.org/10.1084/jem.20102065
https://doi.org/10.1084/jem.20102065
Publikováno v:
Immunological Reviews. 237:90-103
Targeted modification of the mouse genome provides the capability to manipulate complex physiological processes in a precise and controlled manner. Investigation of B-lymphocyte biology has benefited not only from the targeted modification of genes c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ffbd269bd9cb625d73a6de1aa74fefa
https://doi.org/10.1111/j.1600-065x.2010.00942.x
https://doi.org/10.1111/j.1600-065x.2010.00942.x
Autor:
Robert Brink, Cindy S. Ma, Elissa K. Deenick, Stuart G. Tangye, Anna Chan, Dominique Gatto, Pamela L. Schwartzberg
Publikováno v:
Immunity. 33(2):241-253
Summary Effective humoral immunity depends on the support of B cell responses by T follicular helper (Tfh) cells. Although it has been proposed that Tfh cell differentiation requires T-B interactions, the relative contribution of specific populations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcee921d5425042069882afde38b673
Autor:
Philippe Saudan, Melanie Wiesel, Klaus Dietmeier, Martin F. Bachmann, Franziska Zabel, Dominique Gatto, Andrea Jegerlehner
Publikováno v:
Vaccine. 28:5503-5512
Pre-existing immunity against vaccine carrier proteins has been reported to inhibit the immune response against antigens conjugated to the same carrier by a process termed carrier induced epitopic suppression (CIES). Hence understanding the phenomeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b5dddfcc4a2dcac663f076aac84246
https://doi.org/10.1016/j.vaccine.2010.02.103
https://doi.org/10.1016/j.vaccine.2010.02.103
Autor:
Dominique Gatto, Stephen W. Martin, Martin F. Bachmann, Manfred Kopf, Thomas Pfister, Andrea Jegerlehner
Publikováno v:
The Journal of Experimental Medicine
Humoral immune responses are thought to be enhanced by complement-mediated recruitment of the CD21–CD19–CD81 coreceptor complex into the B cell antigen receptor (BCR) complex, which lowers the threshold of B cell activation and increases the surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4632a11aaf142130ed249aa36bbbcabc
https://doi.org/10.1084/jem.20042239
https://doi.org/10.1084/jem.20042239
Autor:
Bill, Giannakopoulos, Peyman, Mirarabshahi, Miao, Qi, Chris, Weatherall, Jian Cheng, Qi, Kumiko, Tanaka, Ewan, Millar, Leon, Vonthethoff, Dominique, Gatto, Derek, Spielman, Steven A, Krilis
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 66(8)
The BXSB.Yaa mouse strain is a model of systemic lupus erythematosus that is dependent on duplication of the Toll-like receptor 7 gene. The objective of this study was to systematically describe the amplified autoimmune phenotype observed when the so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbec9049615aba9ed77afd3a0eae4bf8
https://pubmed.ncbi.nlm.nih.gov/24692206
https://pubmed.ncbi.nlm.nih.gov/24692206
Autor:
Robert Brink, Dominique Gatto
Publikováno v:
Trends in immunology. 34(7)
During antibody responses, B cells undergo a series of migratory events that guide them to the appropriate microenvironments for activation and differentiation. Epstein–Barr virus-induced molecule 2 [EBI2; also known as G-protein-coupled receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc670ac76f844ffd6b0ad825f3638c8
https://pubmed.ncbi.nlm.nih.gov/23481574
https://pubmed.ncbi.nlm.nih.gov/23481574
Autor:
Katherine Wood, Peter R. Schofield, Daniel Christ, Gunasegaran Karupiah, Robert Brink, Irina Caminschi, Danielle Murphy-Durland, Dominique Gatto
Publikováno v:
Nature immunology. 14(5)
Spleen-resident dendritic cell (DC) populations occupy sentinel positions for the capture and presentation of blood-borne antigens. Here we found a difference in expression of the chemotactic receptor EBI2 (GPR183) on splenic DC subsets and that EBI2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e556e211bbc284cd68e0e119720a4659
https://pubmed.ncbi.nlm.nih.gov/23598391
https://pubmed.ncbi.nlm.nih.gov/23598391