Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Dominique Florentin"'
Autor:
Dominique Florentin, Gérard Bolbach, Andrée Marquet, Tony A. Mattioli, Bernadette Tse Sum Bui
Publikováno v:
Biochemistry. 45:3824-3834
Biotin synthase, a member of the "radical SAM" family, catalyzes the final step of the biotin biosynthetic pathway, namely, the insertion of a sulfur atom into dethiobiotin. The as-isolated enzyme contains a [2Fe-2S](2+) cluster, but the active enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8716a7ae88cf3f1b82f07e3d4301b695
https://doi.org/10.1021/bi052388m
https://doi.org/10.1021/bi052388m
Publikováno v:
Biochemical Society Transactions. 33:820-823
Biotin synthase, a member of the ‘radical SAM’ (S-adenosylmethionine) family, converts DTB (dethiobiotin) into biotin. The active form of the Escherichia coli enzyme contains two (Fe-S) centres, a (4Fe-4S) and a (2Fe-2S). The (4Fe-4S)2+/+ mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a497a10aa481ec02762d6ec42eaee52
https://doi.org/10.1042/bst0330820
https://doi.org/10.1042/bst0330820
Autor:
Olivier Ploux, Denis Lesage, Stéphane Mann, Dominique Florentin, Andrée Marquet, Thierry Drujon
Publikováno v:
Helvetica Chimica Acta. 86:3836-3850
The mechanism of action of amiclenomycin (1a), a naturally occuring inhibitor of diaminopelargonic acid aminotransferase, has been established. The enzyme catalyzes the formation of an aromatic adduct between the inhibitor and pyridoxal-5′-phosphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d149da7810e5dc327c53fd76ac7880f4
https://doi.org/10.1002/hlca.200390322
https://doi.org/10.1002/hlca.200390322
Autor:
Andrée Marquet, Riidiger Benda, Volker Schünemann, Alfred X. Trautwein, Bernadette Tse Sum Bui, Dominique Florentin
Publikováno v:
Biochemistry. 42:8791-8798
Biotin synthase, the enzyme which catalyzes the last step of the biosynthesis of biotin, contains only (2Fe-2S)(2+) clusters when isolated under aerobic conditions. Previous results showed that reduction by dithionite or photoreduced deazaflavin conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35226d9890eb646be88ae779ce65f6f3
https://doi.org/10.1021/bi034426c
https://doi.org/10.1021/bi034426c
Publikováno v:
Tetrahedron. 56:285-293
It is now established that the formation of C–S bonds during the conversion of dethiobiotin into biotin involves intermediate carbon radicals. To examine the behavior of dethiobiotin analogs that could lead to allylic and α-epoxyradicals, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50cd465ffb4f8c8fc50de52f92511642
https://doi.org/10.1016/s0040-4020(99)01022-4
https://doi.org/10.1016/s0040-4020(99)01022-4
Autor:
and Denis Lesage, Andrée Marquet, Dominique Florentin, Bernadette Tse Sum Bui, Franck Escalettes
Publikováno v:
Journal of the American Chemical Society. 121:3571-3578
Biotin synthase, the enzyme which catalyses the conversion of dethiobiotin (DTB) to biotin has an absolute requirement for S-adenosylmethionine (AdoMet) which is cleaved into methionine (Met) and 5‘-deoxyadenosine (DOA) in equimolar amounts (Guianv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddaaabb0dbeeb47085627b7301bc6a6a
https://doi.org/10.1021/ja9811748
https://doi.org/10.1021/ja9811748
Publikováno v:
Journal of Carbohydrate Chemistry. 17:1219-1238
The synthesis of 5-O-[5-(pentanoic acid)]-phosphono-L-erythro-pent-2-ulose 2 was successfully achieved by coupling benzyl 5-hydroxypentanoate 9b and 1-O-benzyl-L-erythro-pent-2-ulose ethane- 1,2-diyl dithioacetal 13 with the enediol pyrophosphate 18.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35027c16bd613e8e9f0ea04144c90fb4
https://doi.org/10.1080/07328309808001895
https://doi.org/10.1080/07328309808001895
Publikováno v:
Tetrahedron Letters. 39:7499-7502
Reduction of biotin or epibiotin sulfoxides with nickel boride and deuterated reagents affords as major products bideuterated dethiobiotin. Deuterium localisation by [ 2 H] NMR in a chiral liquid crystal allows the analysis of the stereoselectivity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd4ffbfacd7297d0e6f216d21c9f574
https://doi.org/10.1016/s0040-4039(98)01625-6
https://doi.org/10.1016/s0040-4039(98)01625-6
Publikováno v:
Scopus-Elsevier
The last step in the biosynthesis of biotin involves the formation of carbon–sulfur bonds at non-activated carbons catalyzed by biotin synthase. S-Adenosylmethionine (AdoMet) and an electron source are essentialfor activity in cell-free systems. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79111a668f568ec059b632ebb5e228bb
https://doi.org/10.1002/(sici)1099-1395(199808/09)11:8/9<529::aid-poc44>3.0.co
https://doi.org/10.1002/(sici)1099-1395(199808/09)11:8/9<529::aid-poc44>3.0.co
Publikováno v:
Comptes Rendus. Chimie
Comptes Rendus. Chimie, Académie des sciences (Paris), 1998, série II c, 1, pp.35-40
Comptes Rendus. Chimie, 1998, série II c, 1, pp.35-40
Comptes Rendus. Chimie, Académie des sciences (Paris), 1998, série II c, 1, pp.35-40
Comptes Rendus. Chimie, 1998, série II c, 1, pp.35-40
An hapten 1 designed for the production of catalytic antibodies was synthesized after coupling its precursor 2 to bovine serum albumin (BSA). The conjugates BSA- 2 and BSA- 1 were characterized by MALDI mass spectrometry. This paper shows that beside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bbc512e5793e7a9c42bff0711058b58
https://doi.org/10.1016/s1251-8069(97)86257-4
https://doi.org/10.1016/s1251-8069(97)86257-4