Výsledky vyhledávání - "Dominique Fässler"

Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism-like phenotype

Autor: David P. Wolfer, Lutz Slomianka, Susann Ludewig, Martin Korte, Kang Han, Dominique Fässler, Jakob von Engelhardt, Irmgard Amrein, Max Richter, Ulrike Müller, Michaela K Back, Susanne Erdinger, Vicky Steubler

Publikováno v: The EMBO Journal, 40 (12)
e107471
The EMBO journal
England
The EMBO Journal

The key role of APP for Alzheimer pathogenesis is well established. However, perinatal lethality of germline knockout mice lacking the entire APP family has so far precluded the analysis of its physiological functions for the developing and adult bra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9268a387c9aba6df8c81a779d2e18303
https://pubmed.ncbi.nlm.nih.gov/34188229

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