Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dominique Depré"'
Autor:
Jie Liu, Xiaowei Lu, Shichang Lv, Wei Liu, Cheng-yi Chen, Mareike C. Holland, Xuebao Ji, Dominique Depré, Pieter Westerduin
Publikováno v:
European Journal of Organic Chemistry. 2020:548-551
Autor:
Jef Cuypers, Stijn Wuyts, Syuzanna R. Harutyunyan, Wouter Couck, Wim Vermeulen, Grégori Binot, Dominique Depré, Dirk Van Den Heuvel, Andras Horvath
Publikováno v:
The Journal of organic chemistry. 84(8)
The key macrocyclization step in the synthesis of simeprevir, a hepatitis C virus (HCV) antiviral drug, was studied. N-Boc substitution on the diene precursor changes the site of insertion of the metathesis catalyst and, consequently, the kinetic mod
Autor:
Pieter Westerduin, Xiaowei Lu, Dominique Depré, Wei Liu, Shichang Lv, Cheng-yi Chen, Mareike C. Holland, Jie Liu, Xuebao Ji
Publikováno v:
European Journal of Organic Chemistry. 2020:524-524
Autor:
Jeremy Vandermeersch, Yolande Lang, Dominique Depré, Jean Dubois, Wim A. A. Vermeulen, Raphaël Robiette, Jan Vandevivere, Longchuan Huang
Publikováno v:
Organic letters. 19(6)
A series of tetrasubstituted fluoroalkenes were synthesized in good yield and high E/Z selectivity (up to 96/4) by Wittig reaction between α-heterosubstituted ketones and α-fluorophosphonium ylides. A detailed study of factors that control stereose
Autor:
Dominique Depré, Wim Albert Alex Aelterman, Zhihua Sui, Xun Li, Dominic Ormerod, Andras Horvath, Nareshkumar F. Jain, Ronald K. Russell
Publikováno v:
Organic Process Research & Development. 13:102-105
A novel and economical process was developed for recycling the undesired enantiomer, (S)-2,8-dimethoxy-5-{4-[2-(1-piperidinyl)ethoxy]phenyl}-11,12-dihydro-5H-6,13-dioxabenzo[3,4]cyclohepta[1,2-a]naphthalene (1b) obtained from chiral chromatographic s
Publikováno v:
Organic Process Research & Development. 12:96-100
The titanocene-catalyzed reduction of the lactone 1 into the lactol 2 was studied. This process uses poly(methylhydrosiloxane) as stoichiometric reductant. Thermodynamic and safety data was collected in order to develop a reliable, safe and scalable
Autor:
Koen De Smet, Dominic Ormerod, Tom Govaerts, Dominique Depré, Inge Schorpion, Andras Horvath, and Dirk Van den Heuvel, Carlos Perez-Balado
Publikováno v:
Organic Process Research & Development. 9:356-359
In-line FTIR was applied as a suitable PAT (process analytical technology) to monitor and control the enolate formation step in the one-carbon homologation process of a 4-methylcoumarin with chloromethyl pivalate. The techniques to determine the endp
Autor:
Xun Li, Ronald K. Russell, András Horváth, Nareshkumar Jain, Dominique Depré, Dominic Ormerod, Wim Aelterman, Zhihua Sui
Publikováno v:
Organic Process Research & Development; Jan2009, Vol. 13 Issue 1, p102-105, 4p
Publikováno v:
Organic Process Research & Development; Dec2007, Vol. 12 Issue 1, p96-100, 5p