[Untitled]

Autor: Etienne Delain, Dominique Coulaud, Eric Lecam, Patrick Midoux, Chantal Pichon

Publikováno v: Somatic Cell and Molecular Genetics. 27:27-47

Nucleic acid transfer in mammalian cells is drastically improved with devices which increase their delivery in the cytosol upon endocytosis. In this chapter, we describe the effect on plasmid DNA (pDNA) and oligonucleotide (ODN) transfer, of an histi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f0a3fe416ea1e5ed3b4a5a4bee5a1000
https://doi.org/10.1023/a:1022931923153

Intracellular Signaling Events in CD77-Mediated Apoptosis of Burkitt's Lymphoma Cells

Autor: Corinne Capoulade, Zohair Mishal, Marianne Mangeney, Dominique Coulaud, Cécile Tétaud, Samir Taga, Yann Lécluse, Thomas Tursz, Joëlle Wiels, Linda L. Pritchard, Karine Carlier

Publikováno v: Scopus-Elsevier
Europe PubMed Central

In the hematopoietic system CD77, a glycolipid surface antigen, is restricted to group I Burkitt's lymphoma (BL) cell lines and a subset of germinal center B lymphocytes. Recently, we have reported that recombinant B subunits of Verotoxin, which spec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc6e52292aa29daf19ec4406291ae5c
https://doi.org/10.1182/blood.v90.7.2757

Electron Microscopic Observations of the Effects of Anthraquinone Derivatives on Plasmid DNA

Autor: Elisabeth Morier-Teissier, Jean-Pierre Hénichart, Dominique Coulaud, Etienne Delain, Jean-Luc Bernier

Publikováno v: Journal of Biomolecular Structure and Dynamics. 9:653-666

Electron microscopy was used to analyse the precipitation of DNA observed when mixed with two tripeptide derivatives of mitoxantrone, with or without a 5,8-dihydroxy group (DHQ-GHK and Q-GHK, respectively) on the anthraquinonic ring. This precipitati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba8ee1a6cc0967041472a94d567c686
https://doi.org/10.1080/07391102.1992.10507946

Selective alteration of mitochondrial function by ditercalinium (NSC 335153), a DNA bisintercalating agent

Autor: Evelyne Ségal-Bendirdjian, Dominique Coulaud, Zohar Mishal, Bernard P. Roques, Catherine Esnault, Stephen C. Brown, Jean Bernard Le Pecq

Publikováno v: Biochemical Pharmacology. 39:109-122

The bifunctional intercalator Ditercalinium (NSC 335153) demonstrates an anti-tumoral cytotoxicity markedly different from other intercalating agents. A delayed toxicity is observed in eucaryotic cells, both in vitro and in vivo , at drug concentrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2a018aae6ddb90dd8da6ce5c1714ac
https://doi.org/10.1016/0006-2952(90)90654-4

The Cationic Amphipathic α-Helix of HIV-1 Viral Protein R (Vpr) Binds to Nucleic Acids, Permeabilizes Membranes, and Efficiently Transfects Cells

Autor: Eric Le Cam, Dominique Coulaud, Antoine Kichler, Olivier Danos, Emmanuel Coeytaux

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2003, 278 (20), pp.18110-18116. ⟨10.1074/jbc.m300248200⟩
Journal of Biological Chemistry, 2003, 278 (20), pp.18110-18116. ⟨10.1074/jbc.m300248200⟩

Viral protein R (Vpr) is a small protein of 96 amino acids that is conserved among the lentiviruses human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus. We recently sought to determine whether the karyophilic propert

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae7b97191987b67111c31140a84690e
https://hal.archives-ouvertes.fr/hal-03065319