CF3SO2X (X = Na, Cl) as reagents for trifluoromethylation, trifluoromethylsulfenyl-, -sulfinyl- and -sulfonylation. Part 1: Use of CF3SO2Na

Autor: Hélène Guyon, Hélène Chachignon, Dominique Cahard

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2764-2799 (2017)

Sodium trifluoromethanesulfinate, CF3SO2Na, and trifluoromethanesulfonyl chloride, CF3SO2Cl, are two popular reagents that are widely used for the direct trifluoromethylation of a large range of substrates. Further, these two reagents are employed fo

Externí odkaz: https://doaj.org/article/81d191f855a347bba0ef1033b69773a1

Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective

Autor: Norio Shibata, Andrej Matsnev, Dominique Cahard

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 6, Iss 1, p 65 (2010)

Since the discovery by Yagupolskii and co-workers that S-trifluoromethyl diarylsulfonium salts are effective for the trifluoromethylation of thiophenolates, the design and synthesis of electrophilic trifluoromethylating reagents have been extensively

Externí odkaz: https://doaj.org/article/ca2a1fcad96a471b85994e414e4341aa

Catalytic Stereoconvergent Synthesis of Homochiral β-CF3, β-SCF3, and β-OCF3 Benzylic Alcohols

Autor: Andrej Emanuel Cotman, Pavel A. Dub, Maša Sterle, Matic Lozinšek, Jaka Dernovšek, Živa Zajec, Anamarija Zega, Tihomir Tomašič, Dominique Cahard

Publikováno v: ACS organic & inorganic Au, vol. 2, no. 5, 2022.
ACS Organic & Inorganic Au
ACS Organic & Inorganic Au, 2022, 2 (5), pp.396-404. ⟨10.1021/acsorginorgau.2c00019⟩

International audience; We describe an efficient catalytic strategy for enantio- and diastereoselective synthesis of homochiral β-CF3, β-SCF3, and β-OCF3 benzylic alcohols. The approach is based on dynamic kinetic resolution (DKR) with Noyori–Ik

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e099aaf3ecb2e7659016157da40bcf
https://doi.org/10.1021/acsorginorgau.2c00019

Metal-free regioselective construction of 2-aryl-2H-tetrazol-5-yl difluoromethylene phosphonates

Autor: Shi-Jing Zhai, Jun-An Ma, Dominique Cahard, Fa-Guang Zhang

Publikováno v: Chinese Chemical Letters. 33:863-866

Three bench-stable difluoromethylene phosphonate hydrazones were prepared from simple diethyl(difluoromethyl)phosphonate within two steps in good yields. The [3 + 2] cycloaddition reaction of these diazo precursors with aryl diazonium salts has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00e10d577816a56af9509b3d9a7b6a48
https://doi.org/10.1016/j.cclet.2021.08.007

Amphiphilic Polyfluorinated Amino Ethers from Cyclic Sulfamidates

Autor: Nicolas Marie, Jun-An Ma, Dominique Cahard

Publikováno v: The Journal of organic chemistry. 87(24)

Regioselective ring opening of cyclic sulfamidates was achieved by means of nucleophilic polyfluorinated alkoxides to access achiral and chiral β- and γ-OR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0616d734f5c6493dc1d3e265abb8093
https://pubmed.ncbi.nlm.nih.gov/36417566