Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Dominique Bonnier"'
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Akademický článek
The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition.
Autor: Michaël Ruff, Anthony Leyme, Fabienne Le Cann, Dominique Bonnier, Jacques Le Seyec, Franck Chesnel, Laurent Fattet, Ruth Rimokh, Georges Baffet, Nathalie Théret
Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0139179 (2015)
The increased expression of the Disintegrin and Metalloprotease ADAM12 has been associated with human cancers, however its role remain unclear. We have previously reported that ADAM12 expression is induced by the transforming growth factor, TGF-β an
Externí odkaz: https://doaj.org/article/32d2e83f62bd4946a600658760f68a72
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2
Integration of miRNA‐regulatory networks in hepatic stellate cells identifies TIMP3 as a key factor in chronic liver disease
Autor: Kevin Courtet, Vincent Legagneux, Dominique Bonnier, Fida Azar, Nathalie Théret, Olivier Dameron, Alain Colige, Bassil Dekky
Publikováno v: Liver International
Liver International, Wiley-Blackwell, 2020, 40 (8), pp.2021-2033. ⟨10.1111/liv.14476⟩
Liver International, 2020, 40 (8), pp.2021-2033. ⟨10.1111/liv.14476⟩
International audience; BACKGROUND & AIMS: Activation of hepatic stellate cells (HSC) is a critical process involved in liver fibrosis. Several miRNAs are implicated in gene regulation during this process but their exact and respective contribution i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854d713f877d4e2cef3f64536b8833a5
https://hal.archives-ouvertes.fr/hal-02549948/document
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3
Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival
Autor: Yannick Arlot-Bonnemains, Nathalie Théret, Anthony Leyme, Dominique Bonnier, Katia Bourd-Boittin, Anaïs Falconer
Publikováno v: Molecular Biology of the Cell
ILK is identified as a new partner for ADAM12L cell signaling functions. ADAM12L colocalizes with ILK at focal adhesions and induces the Akt-dependent survival pathway via stimulation of β1 integrins and activation of PI3K. This effect is independen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032379ce3dad66e54e43f645e44b2ae7
http://europepmc.org/articles/PMC3431925
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4
Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta
Autor: Pierre Tufféry, Bernard Mari, Dominique Bonnier, Anthony Leyme, Frédéric Ezan, Katia Bourd-Boittin, Georges Baffet, Michel Samson, Nathalie Théret
Publikováno v: Hepatology. 54:2173-2184
During chronic liver disease, tissue remodeling leads to dramatic changes and accumulation of matrix components. Matrix metalloproteases and their inhibitors have been involved in the regulation of matrix degradation. However, the role of other prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f6dc67e9aa7d23878e6d5c2df3521b
https://doi.org/10.1002/hep.24598
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6
RACK1, a New ADAM12 Interacting Protein
Autor: Annie L'Helgoualc'h, Dominique Bonnier, Katia Bourd-Boittin, Hélène Le Pabic, Nathalie Théret
Publikováno v: Journal of Biological Chemistry. 283:26000-26009
ADAM12 belongs to a disintegrin-like and metalloproteinase-containing protein family that possesses multidomain structures composed of a pro-domain, a metalloprotease, disintegrin-like, cysteine-rich, epidermal growth factor-like, and transmembrane d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81d4bb5143a915343c8c09a254c9bb41
https://doi.org/10.1074/jbc.m709829200
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7
The disintegrin and metalloproteinase ADAM12 contributes to TGF-β signaling through interaction with the type II receptor
Autor: Nathalie Ferrand, Dominique Bonnier, Céline Prunier, Bruno Clément, Azeddine Atfi, Ulla M. Wewer, Nathalie Théret, Emmanuelle Dumont, Frédéric Colland, Annie L'Helgoualc'h
Publikováno v: The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2007, 178 (2), pp.201-8. ⟨10.1083/jcb.200612046⟩
Journal of Cell Biology, 2007, 178 (2), pp.201-8. ⟨10.1083/jcb.200612046⟩
International audience; Transforming growth factor-beta (TGF-beta) regulates a wide variety of biological processes through two types of Ser/Thr transmembrane receptors: the TGF-beta type I receptor and the TGF-beta type II receptor (TbetaRII). Upon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3dd4ebf03f51a27a9d19579a942720
http://europepmc.org/articles/PMC2064440
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8
In silico characterization of the interaction between LSKL peptide, a LAP-TGF-beta derived peptide, and ADAMTS1
Autor: Pierre Tufféry, Gautier Moroy, Nathalie Théret, Dominique Bonnier, Marie-Amandine Laurent
Publikováno v: Computational biology and chemistry. 61
Binding mode of LSKL peptide, in cyan, with ADAMTS1, in wheat color. The nonbonded interactions are represented in yellow dashed lines. The binding sequence of ADAMTS1 is colored in red.Display Omitted We have experimentally shown that TSP-1 domain o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db15fb42534da332c6e5d624c696baed
https://pubmed.ncbi.nlm.nih.gov/26878129
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9
Upregulation of the tumor suppressor gene menin in hepatocellular carcinomas and its significance in fibrogenesis
Autor: Chang Xian Zhang, Bruno Turlin, Bruno Clément, Marie Bérangère Troadec, Antony Le Béchec, Olivier Loréal, Nathalie Théret, Katia Bourd-Boitin, Orlando Musso, Jean J. Leger, Dominique Bonnier, Pierre Zindy, Annie L'Helgoualc'h, Denise Glaise
Publikováno v: Hepatology
Hepatology, 2006, 44 (5), pp.1296-307. ⟨10.1002/hep.21367⟩
Hepatology, Wiley-Blackwell, 2006, 44 (5), pp.1296-307. ⟨10.1002/hep.21367⟩
ResearcherID
Publons
International audience; The molecular mechanisms underlying the progression of cirrhosis toward hepatocellular carcinoma were investigated by a combination of DNA microarray analysis and literature data mining. By using a microarray screening of supp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83617b240be0a034b4354fac5d1f289b
https://doi.org/10.1002/hep.21367
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10
Purification of the Human RARγ Ligand-Binding Domain and Crystallization of Its Complex with All-transRetinoic Acid
Autor: Dino Moras, Valérie Vivat, Marc Ruff, Pierre Chambon, Hinrich Gronemeyer, Thierry Lerouge, Florence Granger, Dominique Bonnier, Jean-Paul Renaud, Natacha Rochel
Publikováno v: Biochemical and Biophysical Research Communications. 230:293-296
A 28-kDa fragment (residues 178-423) of the human retinoic acid receptor gamma, hRARgamma D3E, encompassing the ligand-binding domain (LBD) was overproduced in Escherichia coli and purified as a monomer to more than 95% purity and homogeneity. The Kd
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb7a0f4316b5be31dd835fdb562d34d
https://doi.org/10.1006/bbrc.1996.5787
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