Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Dominique Bollino"'
Autor:
Dominique Bollino, Kanwal Hameed, Anusha Bhat, Arveen Zarrabi, Andrea Casildo, Xinrong Ma, Kayla M Tighe, Brandon Carter-Cooper, Erin T. Strovel, Rena G. Lapidus, Ashkan Emadi
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease without meaningful therapeutic options beyond the first salvage therapy. Targeting PDAC metabolism through amino acid restriction has emerged as a promising new stra
Externí odkaz:
https://doaj.org/article/525655e9405e4d5485db4d740e853fe2
Autor:
Dominique Bollino, J. Preston Claiborne, Kanwal Hameed, Xinrong Ma, Kayla M. Tighe, Brandon Carter-Cooper, Rena G. Lapidus, Erin T. Strovel, Ashkan Emadi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The impact of asparaginases on plasma asparagine and glutamine is well established. However, the effect of asparaginases, particularly those derived from Erwinia chrysanthemi (also called crisantaspase), on circulating levels of other amino acids is
Externí odkaz:
https://doaj.org/article/3adc67d2117c455686dc7b3a50c277d3
Translatome changes in acute myeloid leukemia cells post exposure to pegcrisantaspase and venetoclax
Autor:
Bandish Kapadia, Amol C. Shetty, Dominique Bollino, Binny Bhandary, Rena G. Lapidus, Kanwal Mahmood, Anup Mahurkar, Ronald B. Gartenhaus, Richard L. Eckert, Ashkan Emadi
Publikováno v:
Experimental Hematology. 108:55-63
The clinical outcomes of patients with acute myeloid leukemia (AML) treated with available therapy remain unsatisfactory. We recently reported that the BCL-2 inhibitor venetoclax synergizes with pegcrisantaspase (Ven-PegC) and exhibits remarkable in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea1d0d466d5be58554c17e285884bfb7
https://doi.org/10.1016/j.exphem.2022.01.006
https://doi.org/10.1016/j.exphem.2022.01.006
Autor:
Michelle Lee, Vi Lam, Dana Ferraris, Maria LaRossa-Garcia, Eun Yong Choi, Riley Palmer, Elizabeth T. Chang, Yuji Zhang, Brandon Carter-Cooper, Rena G. Lapidus, Ashkan Emadi, Bandish Kapadia, Kristopher Mason, Smaraki Dash, Farin Kamangar, Dominique Bollino, Yin Jing, Phuc Huu Truong, Nicholas P. Ambulos, Elijah Williams, Olivia Kipe, Ronald B. Gartenhaus
Publikováno v:
Anti-cancer agents in medicinal chemistry. 22(2)
Background: The clinical outcomes of patients with Acute Myeloid Leukemia (AML) remain unsatisfactory. Therefore the development of more efficacious and better-tolerated therapy for AML is critical. We have previously reported anti-leukemic activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07ffae8a0fef0e965911977bf1a5efb
https://pubmed.ncbi.nlm.nih.gov/34080968
https://pubmed.ncbi.nlm.nih.gov/34080968
Autor:
Ashkan, Emadi, Bandish, Kapadia, Dominique, Bollino, Binny, Bhandary, Maria R, Baer, Sandrine, Niyongere, Erin T, Strovel, Hannah, Kaizer, Elizabeth, Chang, Eun Yong, Choi, Xinrong, Ma, Kayla M, Tighe, Brandon, Carter-Cooper, Blake S, Moses, Curt I, Civin, Anup, Mahurkar, Amol C, Shetty, Ronald B, Gartenhaus, Farin, Kamangar, Rena G, Lapidus
Publikováno v:
Leukemia. 35(7)
Complex karyotype acute myeloid leukemia (CK-AML) has a dismal outcome with current treatments, underscoring the need for new therapies. Here, we report synergistic anti-leukemic activity of the BCL-2 inhibitor venetoclax (Ven) and the asparaginase f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27c5b282ff67e6db1f75b329001536c8
https://pubmed.ncbi.nlm.nih.gov/33199836
https://pubmed.ncbi.nlm.nih.gov/33199836
Publikováno v:
Journal of General Virology. 97:496-508
Oncolytic virotherapy is a unique cancer therapeutic that encompasses tumour cell lysis through both virus replication and programmed cell death (PCD) pathways. Nonetheless, clinical efficacy is relatively modest, likely related to the immunosuppress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d7e0cb3ce9c6511c41fae1a8f02302
https://doi.org/10.1099/jgv.0.000353
https://doi.org/10.1099/jgv.0.000353
Publikováno v:
Journal of Neurochemistry. 133:174-186
A growing body of evidence indicates that valproic acid (VPA), a histone deacetylase inhibitor used to treat epilepsy and mood disorders, has histone deacetylase-related and -unrelated neurotoxic activity, the mechanism of which is still poorly under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35483ff99bfdda16aab59d9bcdeb0a1a
https://doi.org/10.1111/jnc.13029
https://doi.org/10.1111/jnc.13029
Autor:
Dominique Bollino, Tonya J. Webb
Publikováno v:
Translational research : the journal of laboratory and clinical medicine. 187
Natural killer (NK) cells of the innate immune system and natural killer T (NKT) cells, which have roles in both the innate and adaptive responses, are unique lymphocyte subsets that have similarities in their functions and phenotypes. Both cell type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46fcd74ebb8f2f0d2977eb522d6b277
https://pubmed.ncbi.nlm.nih.gov/28651074
https://pubmed.ncbi.nlm.nih.gov/28651074
Publikováno v:
Gene therapy
Oncolytic virotherapy is a promising strategy for reducing tumor burden through selective virus replication in rapidly proliferating cells. However, the lysis of slowly replicating cancer stem cells (CSCs), which maintain neoplastic clonality, is rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737d06d12dc1bb490be0f3245774cea9
https://doi.org/10.1038/gt.2014.6
https://doi.org/10.1038/gt.2014.6
Autor:
Dominique Bollino, Tonya J Webb
Publikováno v:
The Journal of Immunology. 202:194.43-194.43
Ovarian cancer is the deadliest gynecologic malignancy worldwide and mortality rates have remained steady despite advances in treatment. A major obstacle for current therapies is overcoming tumor immunosuppression, therefore targeting inhibitory fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba3d32d9a271a4b4d2750dcaa45d75db
https://doi.org/10.4049/jimmunol.202.supp.194.43
https://doi.org/10.4049/jimmunol.202.supp.194.43