Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Dominique Boivin"'
Autor:
Denis Gingras, Georges-Etienne Rivard, Ryan Veitch, Mathieu Provençal, Dominique Boivin, Richard Béliveau, Nancy Berger-Thibault, David P. Labbé
Publikováno v:
Journal of Neuro-Oncology. 97:365-372
The classical treatment scheme for medulloblastoma (MB) is based on a tri-therapy approach consisting of surgical tumor resection, craniospinal axis radiation and chemotherapy. With current treatments relying mainly on non-specific cytotoxic therapy,
Autor:
Dominique Boivin, Nicolas Fontaine, Denis Gingras, Richard Béliveau, Sylvie Lamy, David P. Labbé, Edith Beaulieu
Publikováno v:
Biochemistry. 48:3998-4007
CD133 (prominin-1) is a transmembrane glycoprotein expressed at the surface of normal and cancer stem cells, progenitor cells, rod photoreceptor cells, and a variety of epithelial cells. Although CD133 is widely used as a marker of various somatic an
Autor:
Mathieu Provençal, Denis Gingras, Sylvie Lamy, David P. Labbé, Richard Béliveau, Dominique Boivin
Publikováno v:
The Journal of Nutrition. 139:646-652
Medulloblastoma, the most common malignant brain tumor in children, is a highly metastatic disease, with up to 30% of children having evidence of disseminated disease at presentation. Recently, the hepatocyte growth factor (HGF) and its receptor, the
Autor:
Dominique Boivin, Richard Béliveau, Edith Beaulieu, Jessica Jackson, Denis Gingras, Albert Moghrabi, Martine Côté, Sylvie Lamy, Stéphane Barrette, Simon Lord-Dufour
Publikováno v:
Food Chemistry. 112:374-380
Epidemiological studies have consistently linked abundant consumption of fruits and vegetables to a reduction of the risk of developing several types of cancer. In most cases, however, the identification of specific fruits and vegetables that are res
Autor:
Dominique Boivin, Geneviève Glazier, Denis Gingras, Mathieu Provençal, Richard Béliveau, Edith Beaulieu, David Ratel
Publikováno v:
Thrombosis Research. 115:143-152
Fibrinogen and fibrin are molecules with overlapping roles in blood clotting, fibrinolysis, wound healing, inflammation, matrix and cellular interactions and neoplasia. There is currently much interest in the possible use of fibrinolytic agents in hu
Autor:
Sébastien Gendron, Dominique Boivin, Denis Gingras, Richard Béliveau, David Ratel, Mathieu Provençal, Michel Demeule
Publikováno v:
Archives of Biochemistry and Biophysics. 431:197-206
We have recently shown that Neovastat, an antiangiogenic extract from shark cartilage, stimulates the in vitro activation of plasminogen by facilitating the tissue-type plasminogen activator (tPA)-dependent conversion of plasminogen to plasmin. In th
Publikováno v:
Cancer Chemotherapy and Pharmacology. 54:432-440
Neoangiogenesis is critical to cancer proliferation and metastasis and constitutes an attractive target for cancer therapy. It has previously been demonstrated that hederacolchiside-A1 (HCol-A1), a triterpenoid saponin from Hedera colchica Koch, has
Autor:
Denis Gingras, Albert Moghrabi, Martin Gendron, Dominique Boivin, Richard Béliveau, Yves Théorêt
Publikováno v:
Cancer Letters. 203:35-43
There is increasing evidence that a variety of natural substances derived from the diet may act as potent chemopreventive agents. In this work, we show that DAOY cells, a widely used model of metastatic medulloblastoma (MBL), are highly sensitive to
Autor:
Denis Gingras, Jonathan Michaud-Levesque, Julie Jodoin, Sylvie Lamy, Richard Béliveau, Dominique Boivin, Borhane Annabi, Yanick Bertrand, Michel Demeule
Publikováno v:
Current Medicinal Chemistry-Anti-Cancer Agents. 2:441-463
The concept of cancer prevention by use of naturally occuring substances that could be included in the diet is under investigation as a practical approach towards reducing cancer incidence, and therefore the mortality and morbidity associated with th
Autor:
Philip E. Branton, Megan R. Morrison, Dominique Boivin, Richard C. Marcellus, Emmanuelle Querido
Publikováno v:
Europe PubMed Central
The 34-kDa early-region 4 open reading frame 6 (E4orf6) product of human adenovirus type 5 forms complexes with both the cellular tumor suppressor p53 and the viral E1B 55-kDa protein (E1B-55kDa). E4orf6 can inhibit p53 transactivation activity, as c