Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device

Autor: Brian D. Reed, Michael J. Meyer, Valentin Abramzon, Omer Ad, Pat Adcock, Faisal R. Ahmad, Gün Alppay, James A. Ball, James Beach, Dominique Belhachemi, Anthony Bellofiore, Michael Bellos, Juan Felipe Beltrán, Andrew Betts, Mohammad Wadud Bhuiya, Kristin Blacklock, Robert Boer, David Boisvert, Norman D. Brault, Aaron Buxbaum, Steve Caprio, Changhoon Choi, Thomas D. Christian, Robert Clancy, Joseph Clark, Thomas Connolly, Kathren Fink Croce, Richard Cullen, Mel Davey, Jack Davidson, Mohamed M. Elshenawy, Michael Ferrigno, Daniel Frier, Saketh Gudipati, Stephanie Hamill, Zhaoyu He, Sharath Hosali, Haidong Huang, Le Huang, Ali Kabiri, Gennadiy Kriger, Brittany Lathrop, An Li, Peter Lim, Stephen Liu, Feixiang Luo, Caixia Lv, Xiaoxiao Ma, Evan McCormack, Michele Millham, Roger Nani, Manjula Pandey, John Parillo, Gayatri Patel, Douglas H. Pike, Kyle Preston, Adeline Pichard-Kostuch, Kyle Rearick, Todd Rearick, Marco Ribezzi-Crivellari, Gerard Schmid, Jonathan Schultz, Xinghua Shi, Badri Singh, Nikita Srivastava, Shannon F. Stewman, TR Thurston, T. R. Thurston, Philip Trioli, Jennifer Tullman, Xin Wang, Yen-Chih Wang, Eric A. G. Webster, Zhizhuo Zhang, Jorge Zuniga, Smita S. Patel, Andrew D. Griffiths, Antoine M. van Oijen, Michael McKenna, Matthew D. Dyer, Jonathan M. Rothberg

Publikováno v: Science. 378:186-192

Studies of the proteome would benefit greatly from methods to directly sequence and digitally quantify proteins and detect posttranslational modifications with single-molecule sensitivity. Here, we demonstrate single-molecule protein sequencing using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d3367086ac787e208c4c79a68cbb83f
https://doi.org/10.1126/science.abo7651

Scalable workflows and reproducible data analysis for genomics

Autor: Francesco Strozzi, Dominique Belhachemi, George Githinji, Steffen Möller, Pjotr Prins, Paolo Di Tommaso, Ricardo Wurmus, Roel Janssen, Geert Smant, Joep de Ligt, Michael R. Crusoe

Publikováno v: Evolutionary Genomics
Evolutionary Genomics. Humana Press Inc.
Methods in Molecular Biology ISBN: 9781493990733

Biological, clinical, and pharmacological research now often involves analyses of genomes, transcriptomes, proteomes, and interactomes, within and between individuals and across species. Due to large volumes, the analysis and integration of data gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f603d77bafdaaad9153e3ea1ebdae3
https://research.wur.nl/en/publications/scalable-workflows-and-reproducible-data-analysis-for-genomics

Scalable Computing for Evolutionary Genomics

Autor: Steffen Möller, Dominique Belhachemi, Geert Smant, Pjotr Prins

Publikováno v: Methods in Molecular Biology ISBN: 9781617795848
Evolutionary Genomics. Statistical and Computational Methods, Volume 2
Evolutionary Genomics. Statistical and Computational Methods, Volume 2. Humana Press

Genomic data analysis in evolutionary biology is becoming so computationally intensive that analysis of multiple hypotheses and scenarios takes too long on a single desktop computer. In this chapter, we discuss techniques for scaling computations thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6743e06174d8abac544732c8f32635b9
https://doi.org/10.1007/978-1-61779-585-5_22