Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Dominique Aubry"'
Autor:
Anne-Julie Cloux, Maxime Pellegrin, Karima Bouzourene, Michel A. Duchosal, Christian Widmann, Dominique Aubry, Mathieu Heulot, Michele Cea, Francesco Piacente, Alessio Nencioni, Lucia Mazzolai, Oussama ElMokh, Aimable Nahimana, Axel Bellotti
Publikováno v:
Oncotarget, vol. 10, no. 62, pp. 6723-6738
Oncotarget
Oncotarget
APO866 is a small molecule drug that specifically inhibits nicotinamide phosphoribosyltransferase (NAMPT), a key enzyme involved in nicotinamide adenine dinucleotide (NAD) biosynthesis from the natural precursor nicotinamide. Although, the antitumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4b40cb67b871dadb3d898ba333de97
https://serval.unil.ch/resource/serval:BIB_1BDC3B2158B7.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_1BDC3B2158B7.P001/REF.pdf
Autor:
Dominique Aubry
Publikováno v:
La chaîne d'union. :40-49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::020021c9cdd24a0621eeb3457b67a749
https://doi.org/10.3917/cdu.076.0040
https://doi.org/10.3917/cdu.076.0040
Autor:
Irene Caffa, Caroline S. Breton, Pierre Vogel, Alessio Nencioni, Fabrizio Montecucco, Michel A. Duchosal, Bartosz K. Zambron, Faustino Mollinedo, Michele Cea, Inmaculada Robina, Aimable Nahimana, Consuelo Gajate, Dominique Aubry, Pilar Elías-Rodríguez, Claudia Bello, Jianfei Bai
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
57 p.-9 fig.-2 tab.+Graph. Abst.+Suppl.mat. Bello, Claudia et al.
We have synthesized a wide array of structurally related amphiphilic compounds, containing a functionalized pyrrolidine polar group coupled to different ether-linked hydrocarbon c
We have synthesized a wide array of structurally related amphiphilic compounds, containing a functionalized pyrrolidine polar group coupled to different ether-linked hydrocarbon c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57323b70021f7b3c823e32d79ba0955
http://hdl.handle.net/10261/162835
http://hdl.handle.net/10261/162835
Autor:
Julien Puyal, Christian Widmann, Aimable Nahimana, Michel A. Duchosal, Vanessa Ginet, Caroline S. Breton, Mathieu Heulot, Dominique Aubry
Publikováno v:
Biochimie. 116:141-153
Pancreatic cancer (PC) is one of the most lethal human malignancies and a major health problem. Patients diagnosed with PC and treated with conventional approaches have an overall 5-year survival rate of less than 5%. Novel strategies are needed to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f2ac38bd5c4c78719ea9e0d2106ccb
https://doi.org/10.1016/j.biochi.2015.07.012
https://doi.org/10.1016/j.biochi.2015.07.012
Autor:
Aimable Nahimana, Bernard Sordat, Somi Reddy Majjigapu, Caroline S. Breton, Michel A. Duchosal, Pierre Vogel, Dominique Aubry
Publikováno v:
Leukemia & Lymphoma. 55:2141-2150
APO866 is an inhibitor of nicotinamide adenine dinucleotide (NAD) biosynthesis that exhibits potent anti-lymphoma activity. Rituximab (RTX), an anti-CD20 antibody, kills lymphoma cells by direct apoptosis and antibody- and complement-dependent cell-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45561277c629f1c1fea3dd904c1f367d
https://doi.org/10.3109/10428194.2013.869325
https://doi.org/10.3109/10428194.2013.869325
Autor:
Dominique Aubry
Publikováno v:
La chaîne d'union. :56-65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::598902296337c11b59c533bb9900284c
https://doi.org/10.3917/cdu.043.0056
https://doi.org/10.3917/cdu.043.0056
Autor:
Vincent Kindler, Jacques Cherpillod, Marlies Rüegg, Michel A. Duchosal, Francois Waridel, Véronique Vallet, Dominique Aubry, Marc Schapira, Sandrine Mauray
Publikováno v:
Xenotransplantation. 12:38-48
Background: Models consisting of human immune cells in suspension transferred to severe combined immune deficient (SCID) mice have been invaluable for studying immune response, autoimmunity, and lymphomagenesis. The dissemination of human cells withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05af88b42ace6b37bb4a9788b0eca5ac
https://doi.org/10.1111/j.1399-3089.2004.00191.x
https://doi.org/10.1111/j.1399-3089.2004.00191.x
Autor:
Dominique Aubry
Publikováno v:
La chaîne d'union. :5-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c819106c1bbf4cc688ab65371e1f62
https://doi.org/10.3917/cdu.064.0005
https://doi.org/10.3917/cdu.064.0005
Autor:
Somi Reddy Majjigapu, Anne Julie Cloux, Aimable Nahimana, Coralie Rummel, Julien Puyal, Alessio Nencioni, Michel A. Duchosal, Dominique Aubry, Vanessa Ginet, Caroline S. Breton, Pierre Vogel, Santina Bruzzone, Bernard Sordat
Publikováno v:
Autophagy, vol. 10, no. 4, pp. 603-617
APO866, an inhibitor of NAD biosynthesis, exhibits potent antitumor properties in various malignancies. Recently, it has been shown that APO866 induces apoptosis and autophagy in human hematological cancer cells, but the role of autophagy in APO866-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3484b3dd6cf0f43f6f542c96649afd
https://pubmed.ncbi.nlm.nih.gov/24487122
https://pubmed.ncbi.nlm.nih.gov/24487122