Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Dominique Hebrault"'
Autor:
Peter Sagmeister, Florian F. Ort, Clemens E. Jusner, Dominique Hebrault, Thomas Tampone, Frederic G. Buono, Jason D. Williams, C. Oliver Kappe
Publikováno v:
Advanced Science, Vol 9, Iss 10, Pp n/a-n/a (2022)
Abstract Autonomous flow reactors are becoming increasingly utilized in the synthesis of organic compounds, yet the complexity of the chemical reactions and analytical methods remains limited. The development of a modular platform which uses rapid fl
Externí odkaz:
https://doaj.org/article/51a165848510440db7e0413b28c7d007
Publikováno v:
ACS Sustainable Chemistry & Engineering. 10:5072-5077
Autor:
Davide M. Raimondo, Dominique Hebrault, Keith Chadwick, Des O'grady, Zhilong Zhu, Kwang-Ki K. Kim, Mo Jiang, Michael L. Rasche, Min Hao Wong, Mark C. Molaro, Richard D. Braatz, Lifang Zhou, Xiaoxiang Zhu, Haitao Zhang, John Tedesco
Publikováno v:
Industrial & Engineering Chemistry Research. 53:5325-5336
The evolution of particle shape is an important consideration in many industrial crystallizations. This article describes the design of temperature-cycling experiments (between alternating positive and negative supersaturations) to substantially chan
Autor:
Jon C. Lorenz, Carl A. Busacca, Dominique Hebrault, Nizar Haddad, Chris H. Senanayake, XuWu Feng, Rich Varsolona, Simon Rea, Leen Schellekens, Heewon Lee, Max Sarvestani, Suresh R. Kapadia, Bo Qu
Publikováno v:
Organic Process Research & Development. 19:132-138
A concise scalable synthesis of a chiral dipeptide acid, key substructure of the HCV protease inhibitor faldaprevir, has been developed. A green process with an E-factor of 9.2 was achieved utilizing process analytical technology (PAT) to allow effec
Publikováno v:
New J. Chem.. 28:62-66
A series of mandelic acid derivatives was oxidised by molecular oxygen using cobalt(II) chloride as the catalyst. Benzaldehyde and/or benzoic acid derivatives were obtained in high selectivities, depending on the aromatic ring substitution. Different
Publikováno v:
Tetrahedron Letters. 39:6703-6706
The diazolactone 6b rearranges by treatment with CF3CO2H to give the ketolactone 3b, that, by sequential treatment with lithiated ethyl diazoacetate and AcOH, afforded the ketodiester 15.
Autor:
Dominique Hebrault, Hairuo Peng, Xianglin Shi, Michael Humora, Zhili Xin, William F. Kiesman, Tina Talreja, Zezhou Wang
Publikováno v:
ChemInform. 43
Mild reaction conditions for Petasis reactions of substituted salicylaldehydes with various amines and arylboronic acids in the presence of molecular sieves were developed. Molecular sieves (MS) significantly accelerated the reaction rates and drove
Autor:
William F. Kiesman, Tina Talreja, Michael Humora, Hairuo Peng, Xianglin Shi, Dominique Hebrault, Zhili Xin, Zezhou Wang
Publikováno v:
The Journal of organic chemistry. 77(2)
Mild reaction conditions for Petasis reactions of substituted salicylaldehydes with various amines and arylboronic acids in the presence of molecular sieves were developed. Molecular sieves (MS) significantly accelerated the reaction rates and drove
Publikováno v:
ChemInform. 35
The stereodifferentiating potential of arabinosyl aldimines was utilized in stereoselective syntheses of 2-substituted dehydropiperidinones and their further transformation to 2,6-cis-substituted piperidinones. The absolute configuration was proven b
Publikováno v:
Organic letters. 2(19)
Both enantiomers of methyl dihydrojasmonate (−)-1 and (+)-1 were obtained by a short route using asymmetric Michael addition of dimethyl malonate onto pentyl enone 3, followed by nonracemizing demethoxycarbonylation. The key enantioselective step i