Zobrazeno 1 - 10
of 426
pro vyhledávání: '"Dominique Baeten"'
Autor:
Xenofon Baraliakos, Jerney de Jongh, Denis Poddubnyy, Gerben J. C. Zwezerijnen, Robert Hemke, Sophie Glatt, Stevan Shaw, Lucian Ionescu, Assem el Baghdady, Joanne Mann, Ralph Paul Maguire, Tom Vaux, Natasha de Peyrecave, Marga Oortgiesen, Dominique Baeten, Conny van der Laken
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 16 (2024)
Background: The efficacy and safety of bimekizumab (BKZ), an inhibitor of interleukin (IL)-17F in addition to IL-17A, has been established in axial spondyloarthritis (axSpA). Early assessment of new bone formation is possible using 18 F-fluoride posi
Externí odkaz:
https://doaj.org/article/e1c9ce375eb047a9b8433d9b2c1e2e5f
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Axial spondyloarthritis is a prevalent form of chronic arthritis which is related to psoriatic arthritis and skin psoriasis. TNF and IL-17A as well as IL-17F are key cytokines contributing to the pathobiology of this disease, as evidence by the thera
Externí odkaz:
https://doaj.org/article/3f8f50c98f5c494babbe9d41f9f5c4e3
Autor:
Suzanne Cole, Janine Murray, Catherine Simpson, Remi Okoye, Kerry Tyson, Meryn Griffiths, Dominique Baeten, Stevan Shaw, Asher Maroof
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for inducing IL-17 production in other human immune subsets remains incompletely understood. Mucosal associated invariant T (MAIT) cells uniformly express retin
Externí odkaz:
https://doaj.org/article/9977591d4c7042d0b21fe34563635126
Autor:
Dominique Baeten, Stevan Shaw, Mittal Shah, Asher Maroof, Panos Gikas, Gayatri Mittal, Richard Keen, Scott J Roberts
Publikováno v:
RMD Open, Vol 6, Iss 2 (2020)
Objectives Interleukin (IL)-17 signalling has been shown to be a key regulator of disease in ankylosing spondylitis (AS) with several IL-17 blockers currently clinically approved. Despite this, the role of IL-17 in bone pathology is poorly understood
Externí odkaz:
https://doaj.org/article/3c4af04ceda542ef8d125c3a054f81d0
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-6 (2018)
Abstract Background To be eligible to receive treatment with an anti-tumour necrosis factor (TNF), non-radiographic axial spondyloarthritis (nr-axSpA) patients require either elevated levels of C-reactive protein (CRP) (CRP > upper limit of normal (U
Externí odkaz:
https://doaj.org/article/373227c404e449fa80973676f03ef834
Autor:
Pawel A. Kabala, Chiara Angiolilli, Nataliya Yeremenko, Aleksander M. Grabiec, Barbara Giovannone, Desiree Pots, Timothy R. Radstake, Dominique Baeten, Kris A. Reedquist
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Endoplasmic reticulum (ER) stress has proinflammatory properties, and transgenic animal studies of rheumatoid arthritis (RA) indicate its relevance in the process of joint destruction. Because currently available studies are focus
Externí odkaz:
https://doaj.org/article/4857b92b62ca474c8fd8a4e4519deeee
Autor:
Suzanne Cole, Avneet Manghera, Lachrissa Burns, Janine Barrett, Nicole Yager, Hefin Rhys, Andrew Skelton, John Cole, Carl S. Goodyear, Meryn Griffiths, Dominique Baeten, Marta Bertolini, Stevan Shaw, Hussein Al-Mossawi, Asher Maroof
Publikováno v:
Journal of Allergy and Clinical Immunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::470225974c3fc6a18196446f4d645c7e
https://doi.org/10.1016/j.jaci.2023.03.035
https://doi.org/10.1016/j.jaci.2023.03.035
Autor:
Oliwia Rysnik, Kirsty McHugh, Leonie van Duivenvoorde, Melissa van Tok, Joel Taurog, Simon Kollnberger, Dominique Baeten, Paul Bowness
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 100-111 (2016)
Data is presented showing expression of non-conventional (NC) heavy chain forms of B27 in synovial tissues from SpA patients. Data is presented showing the expression patterns of NC-B27 in joint, gastrointestinal and lymphoid tissues from B27 transge
Externí odkaz:
https://doaj.org/article/921e55d8292846cfa1d4c6391c5d6639
Autor:
Jacqueline E. Paramarta, Maureen C. Turina, Troy Noordenbos, Tanja F. Heijda, Iris C. Blijdorp, Nataliya Yeremenko, Dominique Baeten
Publikováno v:
Journal of Translational Medicine, Vol 14, Iss 1, Pp 1-11 (2016)
Abstract Background To evaluate the immunomodulating and clinical effects of nilotinib, a tyrosine kinase inhibitor, in a proof-of-concept study in spondyloarthritis (SpA) assessing the mast cell as potential novel therapeutic target in this disease.
Externí odkaz:
https://doaj.org/article/722a83161dc94d20834e95355bb29e41
Autor:
Dominique Baeten, Angelique E. A. M. Weel, Janneke J. de Winter, Irene E. van der Horst-Bruinsma, Astrid van Tubergen, Henriëtte M. de Jong, Marleen G H van de Sande, Dirkjan van Schaardenburg, Robert Landewé, Floris A. van Gaalen
Publikováno v:
Arthritis Care & Research, 74, 12, pp. 2076-2084
Arthritis Care & Research, 74, 2076-2084
Arthritis Care & Research, 74(12), 2076-2084. John Wiley & Sons Inc.
Arthritis Care & Research, 74, 2076-2084
Arthritis Care & Research, 74(12), 2076-2084. John Wiley & Sons Inc.
Contains fulltext : 287596.pdf (Publisher’s version ) (Open Access) OBJECTIVE: As first-degree relatives (FDRs) of HLA-B27-positive patients with axial spondyloarthritis (SpA) have an increased risk of developing axial SpA, the objectives were 1) t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7de336d0e67eb4bb1368de2c515681
https://doi.org/10.1002/acr.24743
https://doi.org/10.1002/acr.24743