Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Dominique, de Prost"'
Autor:
Alain Stepanian, Simon Msika, Aurélie Kondratieff, Cécile V. Denis, Dominique de Prost, Muriel Coupaye, Yann Becker, Laurence Salomon, Kevin Zuber, Regis Bobe, Jean-Philippe Rosa, Jose J. Lopez, Christelle Repérant, Marion Pépin, Ziane Elaib
Publikováno v:
Thrombosis and Haemostasis. 119:384-396
In obesity, platelets are described as hyperactive, mainly based on increased platelet size and presence of pro-thrombotic plasmatic molecules. We explored platelet functions, including calcium signalling in obesity, and the effect of weight loss. We
Autor:
Alain Stepanian, Alexandre Alcaïs, Dominique de Prost, Vassilis Tsatsaris, Michel Dreyfus, Jean-Marc Treluyer, Laurent Mandelbrot, ECLAXIR Study Group
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113176 (2014)
Preeclampsia is a frequent medical complication during pregnancy. Corin, a serine protease which activates pro-atrial natriuretic peptide, has recently been shown to be involved in the pathophysiology of preeclampsia. The aim of this study was to sea
Externí odkaz:
https://doaj.org/article/f94856f1b8504209a74a6f63137d0a7c
Autor:
Alain Stepanian, Soraya Benchenni, Tiphaine Beillat-Lucas, Sophie Omnes, Fannie Defay, Edith Peynaud-Debayle, Gabriel Baron, Agnès Le Querrec, Michel Dreyfus, Laurence Salomon, Vassilis Tsatsaris, Dominique de Prost, Laurent Mandelbrot, ECLAXIR study group
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6192 (2009)
BackgroundPreeclampsia and coronary-artery disease share risk factors, suggesting common pathophysiological mechanisms. CX3CR1/CX3CL1 mediates leukocyte migration and adhesion and has been implicated in the pathophysiology of several inflammatory dis
Externí odkaz:
https://doaj.org/article/afc7d0bf34854e6daef6d618b7dd9645
Autor:
Alain Stepanian, Sabiha Hennou, David Hajage, Marie-Christine Alessi, Muriel Coupaye, Laure Bourguignat, Simon Msika, Dominique de Prost, Laurence Salomon
Publikováno v:
Obesity. 21:2236-2243
Objective To clarify the relationships between circulating microparticles (MPs), leukocyte–platelet aggregates (LPAs), obesity, and metabolic abnormalities and evaluate the effect of losing weight on these parameters. Design and Methods In 151 seve
Publikováno v:
Annales de biologie clinique. 71:481-484
A 58-year-old patient, without any notable medical history, except for alcoholism and treated hypertension, developed anemia and leukopenia with macrocytosis. Folate deficiency was diagnosed and subsequently treated. Despite folate supplementation, t
Autor:
Alain Stepanian, Laurent Mandelbrot, Edith Peynaud-Debayle, Gabriel Baron, Beatrice Saposnik, Maud Simansour, Sophie Gandrille, Dominique de Prost
Publikováno v:
Thrombosis Research. 129:152-157
The endothelial protein C receptor (EPCR) plays a crucial role in the anticoagulant and anti-inflammatory effects of the protein C pathway, whereas its soluble form (sEPCR) exhibits opposite properties. High plasma levels of sEPCR have been observed
Autor:
Dominique de Prost, N. Ameziane, Marie Cohen-Moatti, Paulette Legendre, Thibaut Sanglier, Vassilis Tsatsaris, Agnès Veyradier, Laurent Mandelbrot, Alain Stepanian
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 31:1703-1709
Objective— The goal of this study was to search for an association between a desintegrin-like and metalloprotease thrombospondin type 1 motif, member 13 (ADAMTS13) levels and the occurrence of preeclampsia, its characteristics (time-onset and sever
Autor:
Gabriel Baron, Bernard Fraysse, Bernard Meyer, Camille Bodenez, Fannie Defay, Olivier Sterkers, N. Ameziane, Dominique de Prost, Isabelle Mosnier, Evelyne Ferrary, Pierre Bertholon, Alain Robier, Alain Stepanian
Publikováno v:
Audiology and Neurotology. 16:55-66
Objective: The pathogenesis of idiopathic sudden sensorineural hearing loss (ISSHL) remains unknown, but vascular involvement is one of the main hypotheses. The main objective of this study was to investigate the association between ISSHL and cardiov
Autor:
Pauline Jouet, Jérôme Lamoril, Jean-Pierre Farmachidi, N. Ameziane, Benoit Coffin, Jean-Marc Sabate, Raymond Jian, Florence Harnois, Iradj Sobhani, Dominique de Prost, Soulé Jc, Jean-Charles Deybach
Publikováno v:
European Journal of Gastroenterology & Hepatology. 20:748-755
Objectives CX3CR1, the receptor of CX3CL1/fractalkine, is involved in regulation of inflammatory response and the CX3CR1-I249-M280 naturally occurring mutants are associated with altered binding to the ligand. Our aim was to evaluate the frequency of
Autor:
Dominique de Prost, Mohammed Dehbi, Abderrezak Bouchama, Abdelmoneim Eldali, Jean Marie Freyssinet, Fatiha Zobairi, Aaron Kwaasi, Corinne Kunzelmann
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 28:1318-1325
Objectives— We tested the hypothesis that the antithrombotic and cytoprotective effects of recombinant human activated protein C (rhAPC) protect baboons against the lethal effects of heatstroke. Methods and Results— Fourteen anesthetized baboons