Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Dominique, Stehelin"'
Publikováno v:
Oncogene. 22:9156-9164
We have identified the mouse exon VII splice variant of the Ets-1 transcription factor. The variant is expressed in all cell lines which express ets-1, at lower levels, it is also expressed in the mouse embryo in vivo. The corresponding protein, p42E
Publikováno v:
Journal of Biological Chemistry. 277:29386-29398
Stromelysin-1 (matrix metalloproteinase-3) is a member of the matrix metalloproteinase family. Regulation of its gene expression is critical for tissue homeostasis. Patterns of increased co-expression of stromelysin-1 and ETS-1 genes have been observ
Autor:
Dominique Stehelin, Séverine Carrère, Eric Buisine, Anne Flourens, Alexis Verger, Martine Duterque-Coquillaud, René Wintjens, Jean Coll
Publikováno v:
Journal of Biological Chemistry. 276:17181-17189
Jun, Fos, and Ets proteins belong to distinct families of transcription factors that target specific DNA elements often found jointly in gene promoters. Physical and functional interactions between these families play important roles in modulating ge
Autor:
Martine Duterque-Coquillaud, Dominique Stehelin, Xavier Desbiens, Virginie e Vlaeminck-Guillem, Frédérique Dewitte, Séverine Carrère
Publikováno v:
Mechanisms of Development. 91:331-335
The Erg gene belongs to the Ets family encoding a class of transcription factors. To gain new insight on the in vivo functional specificity of the Erg gene within the wide Ets family, we used in situ hybridization to determine its expression pattern
For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presen
Autor:
Claire Montpellier, Christian Lagrou, Jean-Jacques Curgy, Violetta Iotsova, Lionel Dumont, Jean Coll, Séverine Lottin, Eric Adriaenssens, Dominique Stehelin, Thierry Dugimont
Publikováno v:
Oncogene. 16:2395-2401
The developmentally regulated H19 gene displays several remarkable properties: expression of an apparently non-translated mRNA, genomic imprinting (maternal allele only expressed), relaxation of the imprinting and/or epigenetic lesions demonstrated i
Publikováno v:
Journal of Biological Chemistry. 272:26188-26195
The transcription factors Fos, Jun, and Ets regulate the expression of human stromelysin-1 and collagenase-1 genes. Recently, we found that ERG, an Ets family member, activates collagenase-1 gene but not stromelysin-1 by physically interacting with c
Autor:
André Capron, Hector Escriva, Catherine Hänni, Raymond J. Pierce, Dominique Stehelin, Vincent Laudet, Pierre Saumitou-Laprade, Marie-Claire Langlois, Rachid Safi
Publikováno v:
Proceedings of the National Academy of Sciences. 94:6803-6808
The nuclear receptor (NR) superfamily comprises, in addition to ligand-activated transcription factors, members for which no ligand has been identified to date. We demonstrate that orphan receptors are randomly distributed in the evolutionary tree an
Autor:
Françoise Cottrez, Jean Coll, Claire Montpellier, Hervé Groux, Claude Auriault, Brigitte Quatannens, Dominique Stehelin
Publikováno v:
Europe PubMed Central
Epstein-Barr virus (EBV) is a human lymphotropic virus whose main targets have traditionally been described as B lymphocytes and epithelial cells. Here we report the isolation and characterization of largely monoclonal transformed human T-cell lines