Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Dominique, Soldati"'
Autor:
Gabriel Cabral, Bingjian Ren, Hugo Bisio, Dawson Otey, Dominique Soldati-Favre, Kevin M. Brown
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Apicomplexan parasites mobilize ionic calcium (Ca2+) from intracellular stores to promote microneme secretion and facilitate motile processes including gliding motility, invasion, and egress. Recently, a multipass transmembrane protein, ICM1
Externí odkaz:
https://doaj.org/article/a18a1a40b1244acb88a81d0fb053a288
Autor:
Rouaa Ben Chaabene, Matthew Martinez, Alessandro Bonavoglia, Bohumil Maco, Yi-Wei Chang, Gaëlle Lentini, Dominique Soldati-Favre
Publikováno v:
PLoS Biology, Vol 22, Iss 8, p e3002745 (2024)
Rhoptries are specialized secretory organelles conserved across the Apicomplexa phylum, essential for host cell invasion and critical for subverting of host cellular and immune functions. They contain proteins and membranous materials injected direct
Externí odkaz:
https://doaj.org/article/06ed8fb477954bc8abcfc94e0e4ec231
Autor:
Nicolas Dos Santos Pacheco, Albert Tell i Puig, Amandine Guérin, Matthew Martinez, Bohumil Maco, Nicolò Tosetti, Estefanía Delgado-Betancourt, Matteo Lunghi, Boris Striepen, Yi-Wei Chang, Dominique Soldati-Favre
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract In Apicomplexa, rhoptry discharge is essential for invasion and involves an apical vesicle (AV) docking one or two rhoptries to a macromolecular secretory apparatus. Toxoplasma gondii is armed with 10–12 rhoptries and 5-6 microtubule-assoc
Externí odkaz:
https://doaj.org/article/db5a5f1efb7a45248abcc933162e7602
Autor:
María Pía Alberione, Víctor González-Ruiz, Olivier von Rohr, Serge Rudaz, Dominique Soldati-Favre, Luis Izquierdo, Joachim Kloehn
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1011979 (2024)
The cell surface of Toxoplasma gondii is rich in glycoconjugates which hold diverse and vital functions in the lytic cycle of this obligate intracellular parasite. Additionally, the cyst wall of bradyzoites, that shields the persistent form responsib
Externí odkaz:
https://doaj.org/article/fac001c6cfd44a8eace6d286dfd71079
Autor:
Vincent Louvel, Romuald Haase, Olivier Mercey, Marine H. Laporte, Thibaut Eloy, Étienne Baudrier, Denis Fortun, Dominique Soldati-Favre, Virginie Hamel, Paul Guichard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Expansion microscopy (ExM) is a highly effective technique for super-resolution fluorescence microscopy that enables imaging of biological samples beyond the diffraction limit with conventional fluorescence microscopes. Despite the developme
Externí odkaz:
https://doaj.org/article/c6a6a3bb5cfb4d21a6b92a1f7f57c8cd
Autor:
Elena Levashina, Dominique Soldati‐Favre, Andrew P Waters, Friedrich Frischknecht, Julian C Rayner
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-4 (2023)
Graphical Abstract Round table discussion on challenges and opportunities in malaria research with Elena Levashina, Dominique Soldati‐Favre, Andrew Waters, Friedrich Frischknecht, and Julian Rayner.
Externí odkaz:
https://doaj.org/article/eab9fa6986ea4893a6d0164cceae1fc8
Autor:
Matthew Martinez, Shrawan Kumar Mageswaran, Amandine Guérin, William David Chen, Cameron Parker Thompson, Sabine Chavin, Dominique Soldati-Favre, Boris Striepen, Yi-Wei Chang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The phylum Apicomplexa comprises important eukaryotic parasites that invade host tissues and cells using a unique mechanism of gliding motility. Gliding is powered by actomyosin motors that translocate host-attached surface adhesins along th
Externí odkaz:
https://doaj.org/article/13a350adc2704a6a8ba35bd0fb27a960
Autor:
Emma Pietsch, Abhinay Ramaprasad, Sabrina Bielfeld, Yvonne Wohlfarter, Bohumil Maco, Korbinian Niedermüller, Louisa Wilcke, Joachim Kloehn, Markus A. Keller, Dominique Soldati-Favre, Michael J. Blackman, Tim-Wolf Gilberger, Paul-Christian Burda
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTPlasmodium parasites rely on a functional electron transport chain (ETC) within their mitochondrion for proliferation, and compounds targeting mitochondrial functions are validated antimalarials. Here, we localize Plasmodium falciparum patati
Externí odkaz:
https://doaj.org/article/f35cc9f369ff4e73b649d2374544ac7b
Autor:
David J. Dubois, Sylia Chehade, Jean-Baptiste Marq, Kannan Venugopal, Bohumil Maco, Albert Tell I. Puig, Dominique Soldati-Favre, Sabrina Marion
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Members of the Apicomplexa phylum possess specialized secretory organelles that discharge, apically and in a timely regulated manner, key factors implicated in parasite motility, host cell invasion, egress and subversion of host cellular fun
Externí odkaz:
https://doaj.org/article/b80844e8e0704425816ab3f737917706
Autor:
Amit Kumar, Oscar Vadas, Nicolas Dos Santos Pacheco, Xu Zhang, Kin Chao, Nicolas Darvill, Helena Ø Rasmussen, Yingqi Xu, Gloria Meng-Hsuan Lin, Fisentzos A Stylianou, Jan Skov Pedersen, Sarah L Rouse, Marc L Morgan, Dominique Soldati-Favre, Stephen Matthews
Publikováno v:
eLife, Vol 12 (2023)
The phylum of Apicomplexa groups intracellular parasites that employ substrate-dependent gliding motility to invade host cells, egress from the infected cells, and cross biological barriers. The glideosome-associated connector (GAC) is a conserved pr
Externí odkaz:
https://doaj.org/article/0e654b1589534461b1caa8d1eeed76fe