Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Dominique, Missiakas"'
Autor:
Emily Cullum, Yunys Perez-Betancourt, Miaomiao Shi, Eirinaios Gkika, Olaf Schneewind, Dominique Missiakas, Tatyana Golovkina
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012306 (2024)
Staphylococcus aureus is a human-adapted pathogen that replicates by asymptomatically colonizing its host. S. aureus is also the causative agent of purulent skin and soft tissue infections as well as bloodstream infections that result in the metastat
Externí odkaz:
https://doaj.org/article/8d2a16f647b0419ebcc1b4dbec2dfe4e
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT Septal membranes of Staphylococcus aureus serve as the site of secretion for precursors endowed with the YSIRK motif. Depletion of ltaS, a gene required for lipoteichoic acid (LTA) synthesis, results in the loss of restricted trafficking of
Externí odkaz:
https://doaj.org/article/f25b9edb652e4fb5a4c253cecf221b42
Autor:
Lamiaa El-Shennawy, Andrew D. Hoffmann, Nurmaa Khund Dashzeveg, Kathleen M. McAndrews, Paul J. Mehl, Daphne Cornish, Zihao Yu, Valerie L. Tokars, Vlad Nicolaescu, Anastasia Tomatsidou, Chengsheng Mao, Christopher J. Felicelli, Chia-Feng Tsai, Carolina Ostiguin, Yuzhi Jia, Lin Li, Kevin Furlong, Jan Wysocki, Xin Luo, Carolina F. Ruivo, Daniel Batlle, Thomas J. Hope, Yang Shen, Young Kwang Chae, Hui Zhang, Valerie S. LeBleu, Tujin Shi, Suchitra Swaminathan, Yuan Luo, Dominique Missiakas, Glenn C. Randall, Alexis R. Demonbreun, Michael G. Ison, Raghu Kalluri, Deyu Fang, Huiping Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
El-Shennawy et al. report that ACE2+ circulating extracellular vesicles (evACE2) are associated with COVID-19 severity and that evACE2 inhibits the infection of SARS-CoV-2 variants of concern at a higher efficacy than soluble ACE2.
Externí odkaz:
https://doaj.org/article/271c6c97f77947d1a54cafa9338a135a
Autor:
Albertus Viljoen, Felipe Viela, Marion Mathelié-Guinlet, Dominique Missiakas, Giampiero Pietrocola, Pietro Speziale, Yves F. Dufrêne
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Through force spectroscopy studies on living bacteria, Viljoen et al. characterise the binding of S. aureus to host von Willebrand factor (vWF). They propose that S. aureus vWF-binding protein triggers an ultra-strong interaction between the adhesin
Externí odkaz:
https://doaj.org/article/5fb6b6ad101d42848719d50da0b6a208
Autor:
Natalia Malachowa, Will McGuinness, Scott D. Kobayashi, Adeline R. Porter, Carl Shaia, Jamie Lovaglio, Brian Smith, Viktoria Rungelrath, Greg Saturday, Dana P. Scott, Fabiana Falugi, Dominique Missiakas, Olaf Schneewind, Frank R. DeLeo
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 2 (2022)
ABSTRACT Staphylococcus aureus remains a leading cause of skin and soft tissue infections (SSTIs) globally. In the United States, many of these infections are caused by isolates classified as USA300. Our understanding of the success of USA300 as a hu
Externí odkaz:
https://doaj.org/article/3bd61d6df61c4ce5a25836c22438198e
Autor:
Xiaolei Cai, Min Chen, Aleksander Prominski, Yiliang Lin, Nicholas Ankenbruck, Jillian Rosenberg, Mindy Nguyen, Jiuyun Shi, Anastasia Tomatsidou, Glenn Randall, Dominique Missiakas, John Fung, Eugene B. Chang, Pablo Penaloza‐MacMaster, Bozhi Tian, Jun Huang
Publikováno v:
Advanced Science, Vol 9, Iss 2, Pp n/a-n/a (2022)
Abstract The outbreak of 2019 coronavirus disease (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has resulted in a global pandemic. Despite intensive research, the current treatment options show limited cura
Externí odkaz:
https://doaj.org/article/5a87e165b630476b9dfcd6664dc1a5eb
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
ABSTRACT Staphylococcus aureus causes reiterative and chronic persistent infections. This can be explained by the formidable ability of this pathogen to escape immune surveillance mechanisms. Cells of S. aureus display the abundant staphylococcal pro
Externí odkaz:
https://doaj.org/article/9f372872ce4e488c95860d2f26c772c0
Autor:
Dominique Missiakas, Volker Winstel
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Host cell death programs are fundamental processes that shape cellular homeostasis, embryonic development, and tissue regeneration. Death signaling and downstream host cell responses are not only critical to guide mammalian development, they often ac
Externí odkaz:
https://doaj.org/article/df29856cd74e409aa4f8a86263d147f6
Autor:
Manli Na, Zhicheng Hu, Majd Mohammad, Mariana do Nascimento Stroparo, Abukar Ali, Ying Fei, Anders Jarneborn, Peter Verhamme, Olaf Schneewind, Dominique Missiakas, Tao Jin
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Septic arthritis, one of the most dangerous joint diseases, is predominantly caused by Staphylococcus aureus. In contrast, coagulase-negative staphylococci are rarely found in septic arthritis. We hypothesize that coagulases released by S. a
Externí odkaz:
https://doaj.org/article/cd913e0415954e00a89e814833bb6a1a
Autor:
Stefano Mancini, Frank Oechslin, Carmen Menzi, Yok Ai Que, Jorien Claes, Ruth Heying, Tiago Rafael Veloso, Thomas Vanassche, Dominique Missiakas, Olaf Schneewind, Philippe Moreillon, José Manuel Entenza
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 1615-1624 (2018)
Staphylococcus aureus is the leading cause of infective endocarditis (IE). While the role of S. aureus cell-wall associated protein clumping factor A (ClfA) in promoting IE has been already demonstrated, that of the secreted plasma-clotting factors s
Externí odkaz:
https://doaj.org/article/4855cec5dec8479c8dacaf25c336331b