Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dominique, Minet"'
Autor:
Natalie A, Sims, Philippe, Clément-Lacroix, Dominique, Minet, Caroline, Fraslon-Vanhulle, Martine, Gaillard-Kelly, Michèle, Resche-Rigon, Roland, Baron
Publikováno v:
Journal of Clinical Investigation. 111:1319-1327
Although the role of estradiol in maintaining bone mass is well established, the relative contributions of the estradiol receptors ERalpha and ERbeta and of the androgen receptor (AR) remain controversial. To determine the role of ERalpha-mediated, E
Autor:
Francois Nique, Denis Guédin, Nicolas Triballeau, Eric Duval, Jean-Michel Lemoullec, Denis Annoot, Catherine Robin-Jagerschmidt, Maxime Thauvin, Jean-Michel Lefrancois, Thierry Prangé, Laurence Michoux, Philippe Clément-Lacroix, Damien Fleury, Pierre Deprez, Patrick Mollat, Séverine Hebbe, Dominique Minet, Christophe Peixoto
Publikováno v:
Journal of medicinal chemistry. 55(19)
A novel selective androgen receptor modulator scaffold has been discovered through structural modifications of hydantoin antiandrogens. Several 4-(4-hydroxyphenyl)-N-arylhydantoins displayed partial agonism with nanomolar in vitro potency in transact
Autor:
Dominique Minet, Roland Baron, S Dupont, A Krust, P Clement-Lacroix, Martine Gaillard-Kelly, Michèle Resche-Rigon, Natalie A. Sims
Publikováno v:
Bone. 30(1)
To determine the contributions of estrogen receptor (ER)alpha and ERbeta in bone growth and remodeling in male and female mice, we generated and analyzed full knockouts for each receptor, and a double ER knockout. Although suppression of the ligand t
Autor:
D. Merciris, L. Lepescheux, Roland Blanque, C. Cottereaux, M. Auberval, Philippe Delerive, Dominique Minet, Philippe Clément-Lacroix, Florence Namour
Publikováno v:
BMC Musculoskeletal Disorders
Background Muscle wasting is a hallmark of many chronic conditions but also of aging and results in a progressive functional decline leading ultimately to disability. Androgens, such as testosterone were proposed as therapy to counteract muscle atrop