Zobrazeno 1 - 10
of 481
pro vyhledávání: '"Dominique, Heymann"'
Autor:
Lisa Oliver, Yuna Landais, Catherine Gratas, Pierre-François Cartron, François Paris, Dominique Heymann, François M. Vallette, Aurelien Serandour
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Background The interaction between mesenchymal stem cells (MSC) and Glioblastoma (GBM), although potentially of the highest importance, is ill-understood. This is due, in part, to the lack of relevant experimental models. The similarity betw
Externí odkaz:
https://doaj.org/article/6c267ab48d44485a92ba4348d55c821e
Autor:
Verónica Rey, Juan Tornín, Juan Jose Alba-Linares, Cristina Robledo, Dzohara Murillo, Aida Rodríguez, Borja Gallego, Carmen Huergo, Cristina Viera, Alejandro Braña, Aurora Astudillo, Dominique Heymann, Karoly Szuhai, Judith V.M.G. Bovée, Agustín F. Fernández, Mario F. Fraga, Javier Alonso, René Rodríguez
Publikováno v:
EBioMedicine, Vol 102, Iss , Pp 105090- (2024)
Summary: Background: Sarcomas represent an extensive group of malignant diseases affecting mesodermal tissues. Among sarcomas, the clinical management of chondrosarcomas remains a complex challenge, as high-grade tumours do not respond to current the
Externí odkaz:
https://doaj.org/article/a9bcedfaab4940eeb62fdf6d5e65245e
Autor:
Isidora Panez-Toro, Dominique Heymann, François Gouin, Jérôme Amiaud, Marie-Françoise Heymann, Luis A. Córdova
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Classically, particle-induced periprosthetic osteolysis at the implant–bone interface has explained the aseptic loosening of joint replacement. This response is preceded by triggering both the innate and acquired immune response with subsequent act
Externí odkaz:
https://doaj.org/article/482aa1cf88224c298212f3b527e8f2f8
Autor:
Camille Jubelin, Javier Muñoz-Garcia, Denis Cochonneau, Emilie Ollivier, François Vallette, Marie-Françoise Heymann, Lisa Oliver, Dominique Heymann
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: The mechanisms involved in cancer initiation, progression, drug resistance, and disease recurrence are traditionally investigated through in vitro adherent monolayer (2D) cell models. However, solid malignant tumor growth is characteriz
Externí odkaz:
https://doaj.org/article/5be8afa603d64990a6df9702d6a2bb23
Autor:
Camille Jubelin, Javier Muñoz-Garcia, Laurent Griscom, Denis Cochonneau, Emilie Ollivier, Marie-Françoise Heymann, François M. Vallette, Lisa Oliver, Dominique Heymann
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-28 (2022)
Abstract Cancer is a multifactorial disease that is responsible for 10 million deaths per year. The intra- and inter-heterogeneity of malignant tumors make it difficult to develop single targeted approaches. Similarly, their diversity requires variou
Externí odkaz:
https://doaj.org/article/84b740defb9b4117a2050fe94319241d
Autor:
Maria-Bernadette Madel, Julia Halper, Lidia Ibáñez, Lozano Claire, Matthieu Rouleau, Antoine Boutin, Adrien Mahler, Rodolphe Pontier-Bres, Thomas Ciucci, Majlinda Topi, Christophe Hue, Jerome Amiaud, Salvador Iborra, David Sancho, Dominique Heymann, Henri-Jean Garchon, Dorota Czerucka, Florence Apparailly, Isabelle Duroux-Richard, Abdelilah Wakkach, Claudine Blin-Wakkach
Publikováno v:
eLife, Vol 12 (2023)
Bone destruction is a hallmark of chronic inflammation, and bone-resorbing osteoclasts arising under such a condition differ from steady-state ones. However, osteoclast diversity remains poorly explored. Here, we combined transcriptomic profiling, di
Externí odkaz:
https://doaj.org/article/6083ac1d14ed43ab8fc05c983bd5338d
Autor:
Clément J.F. Heymann, Christine Bobin-Dubigeon, Javier Muñoz-Garcia, Denis Cochonneau, Emilie Ollivier, Marie-Françoise Heymann, Dominique Heymann
Publikováno v:
Journal of Bone Oncology, Vol 36, Iss , Pp 100451- (2022)
Osteosarcoma (OS) is a rare malignant primary bone tumours characterized by a high genetic and cell composition heterogeneity. Unfortunately, despite the use of drug combinations and the recent development of immunotherapies, the overall survival has
Externí odkaz:
https://doaj.org/article/fc7bf4d197b84970a04d270624959e68
Autor:
Alejandro Rodríguez‐Pena, Estibaliz Armendariz, Alvaro Oyarbide, Xabier Morales, Sergio Ortiz‐Espinosa, Borja Ruiz‐Fernández de Córdoba, Denis Cochonneau, Iñaki Cornago, Dominique Heymann, Josepmaría Argemi, Delia D'Avola, Bruno Sangro, Fernando Lecanda, Ruben Pio, Iván Cortés‐Domínguez, Carlos Ortiz‐de‐Solórzano
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 3, Pp n/a-n/a (2022)
Abstract The analysis of circulating tumor cells (CTCs) in blood is a powerful noninvasive alternative to conventional tumor biopsy. Inertial‐based separation is a promising high‐throughput, marker‐free sorting strategy for the enrichment and i
Externí odkaz:
https://doaj.org/article/1498d884b7d84603aabdfa1c8f01ba77
Autor:
Marion Rabé, Lucie Fonteneau, Lisa Oliver, Alvaro Morales-Molina, Camille Jubelin, Javier Garcia-Castro, Dominique Heymann, Catherine Gratas, François M. Vallette
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
We have observed a drug-tolerant/persister state in a human glioblastoma (GBM) cell line after exposure to temozolomide, the standard-of-care chemotherapeutic agent for GBM. We used a multicolor lentiviral genetic barcode labeling to follow cell popu
Externí odkaz:
https://doaj.org/article/af10a72ecb07478da8fef7c1d545335e
Autor:
Joséphine Briand, Aurélien A. Sérandour, Arulraj Nadaradjane, Gwenola Bougras-Cartron, Dominique Heymann, Benjamin Ory, François M. Vallette, Pierre-François Cartron
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 72-83 (2020)
MicroRNAs (miRNAs or miRs) play crucial roles in biological and pathological processes. Some miRNAs also appear as promising biomarkers and therapeutic tools. However, the epitranscriptomic regulation of miRNAs is not yet fully elucidated in all of t
Externí odkaz:
https://doaj.org/article/1923c4a8e922482c889c4a8688391f88